Publications by authors named "Jan Picha"

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The final walk with preptin.
Lucie Mrázková, Marta Lubos, Jan Voldřich, Erika Kužmová, Denisa Zrubecká

PLoS One· September 2024

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Combinatorial Libraries of Bipodal Binders of the Insulin Receptor.
Irena Selicharová, Benjamin Fabre, María Soledad Garre Hernández, Marta Lubos, Jan Pícha

ChemMedChem· June 2024

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Modulation of the antagonistic properties of an insulin mimetic peptide by disulfide bridge modifications.
Marta Lubos, Jan Pícha, Irena Selicharová, Jíří Žák, Miloš Buděšínský

J Pept Sci· July 2023

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Functional stapled fragments of human preptin of minimised length.
Marta Lubos, Lucie Mrázková, Petra Gwozdiaková, Jan Pícha, Miloš Buděšínský

Org Biomol Chem· March 2022

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Insulin Analogues with Altered Insulin Receptor Isoform Binding Specificities and Enhanced Aggregation Stabilities.
Terezie Páníková, Katarína Mitrová, Tereza Halamová, Karolína Mrzílková, Jan Pícha

J Med Chem· October 2021

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Acid-Stable Ester Linkers for the Solid-Phase Synthesis of Immobilized Peptides.
Jan Pícha, Miloš Buděšínský, Katarína Mitrová, Jiří Jiráček

Chempluschem· June 2020

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Evaluation of silica from different vendors as the solid support of anion-exchange chiral stationary phases by means of preferential sorption and liquid chromatography.
Michal Kohout, Štěpán Hovorka, Jana Herciková, Maciej Wilk, Petr Sysel

J Sep Sci· December 2019

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A versatile insulin analog with high potency for both insulin and insulin-like growth factor 1 receptors: Structural implications for receptor binding.
Martina Chrudinová, Lenka Žáková, Aleš Marek, Ondřej Socha, Miloš Buděšínský

J Biol Chem· October 2018

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Effect of different immobilization strategies on chiral recognition properties of Cinchona-based anion exchangers.
Michal Kohout, Stefanie Wernisch, Jiří Tůma, Hubert Hettegger, Jan Pícha

J Sep Sci· March 2018

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Insulin-like Growth Factor 1 Analogs Clicked in the C Domain: Chemical Synthesis and Biological Activities.
Kateřina Macháčková, Michaela Collinsová, Martina Chrudinová, Irena Selicharová, Jan Pícha

J Med Chem· December 2017

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Optimized syntheses of Fmoc azido amino acids for the preparation of azidopeptides.
Jan Pícha, Miloš Buděšínský, Kateřina Macháčková, Michaela Collinsová, Jiří Jiráček

J Pept Sci· March 2017

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Synthesis and Evaluation of a Library of Trifunctional Scaffold-Derived Compounds as Modulators of the Insulin Receptor.
Benjamin Fabre, Jan Pícha, Václav Vaněk, Irena Selicharová, Martina Chrudinová

ACS Comb Sci· December 2016

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A CuAAC-Hydrazone-CuAAC Trifunctional Scaffold for the Solid-Phase Synthesis of Trimodal Compounds: Possibilities and Limitations.
Benjamin Fabre, Jan Pícha, Václav Vaněk, Miloš Buděšínský, Jiří Jiráček

Molecules· October 2015

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Mono-N-acyl-2,6-diaminopimelic acid derivatives: analysis by electromigration and spectroscopic methods and examination of enzyme inhibitory activity.
Jan Hlaváček, Miloslava Vítovcová, Petra Sázelová, Jan Pícha, Václav Vaněk

Anal Biochem· December 2014

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The development of a new class of inhibitors for betaine-homocysteine S-methyltransferase.
Jan Pícha, Václav Vaněk, Miloš Buděšínský, Jana Mládková, Timothy A Garrow

Eur J Med Chem· July 2013

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S1 pocket fingerprints of human and bacterial methionine aminopeptidases determined using fluorogenic libraries of substrates and phosphorus based inhibitors.
Marcin Poreba, Anna Gajda, Jan Picha, Jiri Jiracek, Aline Marschner

Biochimie· March 2012

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Unusual activity pattern of leucine aminopeptidase inhibitors based on phosphorus containing derivatives of methionine and norleucine.
Jan Pícha, Radek Liboska, Miloš Buděšínský, Jiři Jiráček, Małgorzata Pawełczak

J Enzyme Inhib Med Chem· April 2011

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Synthesis of α-carboxyphosphinopeptides derived from norleucine.
Jan Pícha, Miloš Buděšínský, Pavel Fiedler, Miloslav Sanda, Jiří Jiráček

Amino Acids· November 2010

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Potency of novel oximes to reactivate sarin inhibited human cholinesterases.
Daniel Jun, Kamil Kuca, Jan Picha, Vit Koleckar, Jan Marek

Drug Chem Toxicol· February 2008

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Reactivation potency of new group of acetylcholinesterase reactivators and their comparison with currently available oximes.
Kamil Kuca, Jan Pícha, Daniel Jun

Acta Medica (Hradec Kralove)· June 2007

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Electroreduction of aromatic oximes: diprotonation, adsorption, imine formation, and substituent effects.
Hayati Celik, Guler Ekmekci, Jiri Ludvík, Jan Pícha, Petr Zuman

J Phys Chem B· April 2006

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A new group of monoquaternary reactivators of acetylcholinesterase inhibited by nerve agents.
Jan Picha, Kamil Kuca, Milan Kivala, Michal Kohout, Jiri Cabal

J Enzyme Inhib Med Chem· June 2005

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