Publications by authors named "Radek Liboska"

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Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapy.
Milan Dejmek, Andrea Brazdova, Tomáš Otava, Marketa Pimkova Polidarova, Martin Klíma, Radek Liboska

Eur J Med Chem· November 2023

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Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists.
Zdeněk Vavřina, Pavla Perlíková, Nemanja Milisavljević, Florian Chevrier, Miroslav Smola, Radek Liboska

J Med Chem· October 2022

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Enzymatic Synthesis of 3'-5', 3'-5' Cyclic Dinucleotides, Their Binding Properties to the Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations.
Barbora Novotná, Lucie Holá, Monika Staś, Ondrej Gutten, Miroslav Smola, Radek Liboska

Biochemistry· December 2021

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Enzymatic Preparation of 2'-5',3'-5'-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations.
Barbora Novotná, Lenka Vaneková, Martin Zavřel, Miloš Buděšínský, Milan Dejmek, Radek Liboska

J Med Chem· December 2019

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Solid-Phase Synthesis of Phosphorothioate/Phosphonothioate and Phosphoramidate/Phosphonamidate Oligonucleotides.
Ondřej Kostov, Radek Liboska, Ondřej Páv, Pavel Novák, Ivan Rosenberg

Molecules· May 2019

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Tuning the hybridization properties of modified oligonucleotides: from flexible to conformationally constrained phosphonate internucleotide linkages.
Ondřej Páv, Ivan Barvík, Radek Liboska, Magdalena Petrová, Ondřej Šimák

Org Biomol Chem· January 2017

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4-Toluenesulfonyloxymethyl-(H)-phosphinate: A Reagent for the Introduction of O- and S-Methyl-(H)-phosphinate Moieties.
Ondřej Kostov, Ondřej Páv, Miloš Buděšínský, Radek Liboska, Ondřej Šimák

Org Lett· June 2016

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The Fingerprint of Anti-Bromodeoxyuridine Antibodies and Its Use for the Assessment of Their Affinity to 5-Bromo-2'-Deoxyuridine in Cellular DNA under Various Conditions.
Anna Ligasová, Radek Liboska, Ivan Rosenberg, Karel Koberna

PLoS One· April 2016

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Dr Jekyll and Mr Hyde: a strange case of 5-ethynyl-2'-deoxyuridine and 5-ethynyl-2'-deoxycytidine.
Anna Ligasová, Radek Liboska, David Friedecký, Kateřina Mičová, Tomáš Adam

Open Biol· January 2016

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Straightforward Synthesis of Purine 4'-Alkoxy-2'-deoxynucleosides: First Report of Mixed Purine-Pyrimidine 4'-Alkoxyoligodeoxynucleotides as New RNA Mimics.
Magdalena Petrová, Ondřej Páv, Miloš Buděšínský, Eva Zborníková, Pavel Novák, Radek Liboska

Org Lett· July 2015

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5'-O-Methylphosphonate nucleic acids--new modified DNAs that increase the Escherichia coli RNase H cleavage rate of hybrid duplexes.
Hana Šipova, Tomaš Špringer, Dominik Rejman, Ondřej Šimak, Magdalena Petrová, Radek Liboska

Nucleic Acids Res· April 2014

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Inhibition of human thymidine phosphorylase by conformationally constrained pyrimidine nucleoside phosphonic acids and their "open-structure" isosteres.
Ivana Košiová, Ondřej Šimák, Natalya Panova, Miloš Buděšínský, Magdalena Petrová, Radek Liboska

Eur J Med Chem· March 2014

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Most anti-BrdU antibodies react with 2'-deoxy-5-ethynyluridine -- the method for the effective suppression of this cross-reactivity.
Radek Liboska, Anna Ligasová, Dmytro Strunin, Ivan Rosenberg, Karel Koberna

PLoS One· June 2013

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Atomic scissors: a new method of tracking the 5-bromo-2'-deoxyuridine-labeled DNA in situ.
Anna Ligasová, Dmytro Strunin, Radek Liboska, Ivan Rosenberg, Karel Koberna

PLoS One· June 2013

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4'-Alkoxy oligodeoxynucleotides: a novel class of RNA mimics.
Radek Liboska, Jan Snášel, Ivan Barvík, Miloš Buděšínský, Radek Pohl

Org Biomol Chem· December 2011

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Unusual activity pattern of leucine aminopeptidase inhibitors based on phosphorus containing derivatives of methionine and norleucine.
Jan Pícha, Radek Liboska, Miloš Buděšínský, Jiři Jiráček, Małgorzata Pawełczak

J Enzyme Inhib Med Chem· April 2011

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Chiral phosphonate internucleotide linkage: a promising modification for chimeric oligonucleotides?
Radek Liboska, Magdalena Petrová, Radek Pohl, Milos Budesínsky, Vladimíra Hurychová

Nucleic Acids Symp Ser (Oxf)· November 2010

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Prolinol-based nucleoside phosphonic acids: synthesis and properties.
Václav Vanĕk, Milos Budĕsínský, Radek Liboska, Vladimíra Hurychová, Ivan Rosenberg

Nucleic Acids Symp Ser (Oxf)· November 2010

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Nucleoside phosphonic acids in thymidine phosphorylase inhibition: structure-activity relationship.
Natalya Panova, Ivana Kosiová, Magdalena Petrová, Václav Vanĕk, Radek Liboska

Nucleic Acids Symp Ser (Oxf)· November 2010

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Structural diversity of nucleoside phosphonic acids as a key factor in the discovery of potent inhibitors of rat T-cell lymphoma thymidine phosphorylase.
Petr Kocalka, Dominik Rejman, Václav Vanek, Markéta Rinnová, Ivana Tomecková, Radek Liboska

Bioorg Med Chem Lett· February 2010

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Investigating oligonucleotide hybridization at subnanomolar level by surface plasmon resonance biosensor method.
Hana Vaisocherová, Alice Zítová, Markéta Lachmanová, Josef Stepánek, Sárka Králíková, Radek Liboska

Biopolymers· July 2006

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Oligomerization aiming at phosphonate analogues of oligoadenylates.
Martina Pressová, Radek Liboska, Milos Budesínský, Sárka Králíková, Ivana Kavenová

Nucleosides Nucleotides Nucleic Acids· December 2003

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Hybridization properties of 4'-branched oligonucleotides.
Radek Liboska, Milos Budesínský, Ivana Dvoráková-Kavenová, Ondrej Páv, Ivan Rosenberg

Nucleosides Nucleotides Nucleic Acids· December 2003

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