Publications by authors named "Timothy C Thompson"

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Vesicle-mediated mitochondrial clearance presents an actionable metabolic vulnerability in triple-negative breast cancer.
Jody Vykoukal, Yihui Chen, Mingxin Zuo, Riccardo Ballarò, Monica J Hong, Timothy C Thompson

Cell Rep Med· December 2025

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Editorial Expression of Concern: Caveolin-1 is regulated by c-myc and suppresses c-myc-induced apoptosis.
Terry L Timme, Alexei Goltsov, Salahaldin Tahir, Likun Li, Jianxiang Wang, Timothy C Thompson

Oncogene· March 2025

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Editorial Expression of Concern: E1A-induced apoptosis does not prevent replication of adenoviruses with deletion of E1b in majority of infected cancer cells.
Xiao-Mei Rao, Michael T Tseng, Xinyu Zheng, Yanbin Dong, Azemat Jamshidi-Parsian, Timothy C Thompson

Cancer Gene Ther· January 2025

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Validation of a prognostic blood-based sphingolipid panel for men with localized prostate cancer followed on active surveillance.
Justin R Gregg, Lisa Newcomb, Ranran Wu, Jennifer Dennison, John W Davis, Timothy C Thompson

Biomark Res· November 2024

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Nutrient scavenging-fueled growth in pancreatic cancer depends on caveolae-mediated endocytosis under nutrient-deprived conditions.
Adam R Wolfe, Tiantian Cui, Sooin Baie, Sergio Corrales-Guerrero, Amy Webb, Timothy C Thompson

Sci Adv· March 2024

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SPOP Mutations Target STING1 Signaling in Prostate Cancer and Create Therapeutic Vulnerabilities to PARP Inhibitor-Induced Growth Suppression.
Chuandong Geng, Man-Chao Zhang, Ganiraju C Manyam, Jody V Vykoukal, Johannes F Fahrmann, Timothy C Thompson

Clin Cancer Res· November 2023

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The lactate-NAD axis activates cancer-associated fibroblasts by downregulating p62.
Juan F Linares, Tania Cid-Diaz, Angeles Duran, Marta Osrodek, Anxo Martinez-Ordoñez, Timothy C Thompson

Cell Rep· May 2022

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PARP and CDK4/6 Inhibitor Combination Therapy Induces Apoptosis and Suppresses Neuroendocrine Differentiation in Prostate Cancer.
Cheng Wu, Shan Peng, Patrick G Pilié, Chuandong Geng, Sanghee Park, Timothy C Thompson

Mol Cancer Ther· September 2021

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ATR Inhibition Induces CDK1-SPOP Signaling and Enhances Anti-PD-L1 Cytotoxicity in Prostate Cancer.
Zhe Tang, Patrick G Pilié, Chuandong Geng, Ganiraju C Manyam, Guang Yang, Timothy C Thompson

Clin Cancer Res· September 2021

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Cytopathic effects and local immune responses in repeated neoadjuvant HSV- + ganciclovir gene therapy for prostate cancer.
Nobuyuki Yanagisawa, Takefumi Satoh, Ken-Ichi Tabata, Hideyasu Tsumura, Yasutomo Nasu, Timothy C Thompson

Asian J Urol· July 2021

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Optimizing the diagnosis and management of ductal prostate cancer.
Weranja Ranasinghe, Daniel D Shapiro, Miao Zhang, Tharakeswara Bathala, Nora Navone, Timothy C Thompson

Nat Rev Urol· June 2021

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Considering the potential for gene-based therapy in prostate cancer.
Justin R Gregg, Timothy C Thompson

Nat Rev Urol· March 2021

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Genome-wide DNA methylation profiling of leukocytes identifies CpG methylation signatures of aggressive prostate cancer.
Yuyan Han, Mutian Zhang, Junfeng Xu, Jia Li, Yifan Xu, Timothy C Thompson

Am J Cancer Res· March 2021

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Ductal Prostate Cancers Demonstrate Poor Outcomes with Conventional Therapies.
Weranja Ranasinghe, Daniel D Shapiro, Hyunsoo Hwang, Xuemei Wang, Chad A Reichard, Timothy C Thompson

Eur Urol· February 2021

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Genetic variants in epithelial-mesenchymal transition genes as predictors of clinical outcomes in localized prostate cancer.
Yang Deng, Kunlin Xie, Christopher J Logothetis, Timothy C Thompson, Jeri Kim

Carcinogenesis· August 2020

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Caveolin-1-mediated sphingolipid oncometabolism underlies a metabolic vulnerability of prostate cancer.
Jody Vykoukal, Johannes F Fahrmann, Justin R Gregg, Zhe Tang, Spyridon Basourakos, Timothy C Thompson

Nat Commun· August 2020

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Caveolin and lipid domains-close companions in managing cellular pathways.
Jody V Vykoukal, Johannes F Fahrmann, Timothy C Thompson

Cancer Metastasis Rev· June 2020

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Mitochondrial DNA copy number in peripheral blood leukocytes is associated with biochemical recurrence in prostate cancer patients in African Americans.
Junfeng Xu, Wen-Shin Chang, Chia-Wen Tsai, Da-Tian Bau, John W Davis, Timothy C Thompson

Carcinogenesis· May 2020

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Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma.
Pavlos Msaouel, Gabriel G Malouf, Xiaoping Su, Hui Yao, Durga N Tripathi, Timothy C Thompson

Cancer Cell· May 2020

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Leukocyte telomere length is associated with aggressive prostate cancer in localized prostate cancer patients.
Junfeng Xu, Wen-Shin Chang, Chia-Wen Tsai, Da-Tian Bau, Yifan Xu, Timothy C Thompson

EBioMedicine· February 2020

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PARP Inhibition Suppresses GR-MYCN-CDK5-RB1-E2F1 Signaling and Neuroendocrine Differentiation in Castration-Resistant Prostate Cancer.
Bo Liu, Likun Li, Guang Yang, Chuandong Geng, Yong Luo, Timothy C Thompson

Clin Cancer Res· November 2019

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Driver network as a biomarker: systematic integration and network modeling of multi-omics data to derive driver signaling pathways for drug combination prediction.
Lei Huang, David Brunell, Clifford Stephan, James Mancuso, Xiaohui Yu, Timothy C Thompson

Bioinformatics· October 2019

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Cabazitaxel plus carboplatin for the treatment of men with metastatic castration-resistant prostate cancers: a randomised, open-label, phase 1-2 trial.
Paul G Corn, Elisabeth I Heath, Amado Zurita, Naveen Ramesh, Lianchun Xiao, Timothy C Thompson

Lancet Oncol· October 2019

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N-MYC regulation of DNA damage response in neuroendocrine prostate cancer: mechanistic insight and novel combination therapy approaches.
Timothy C Thompson, Bo Liu, Likun Li

Oncoscience· November 2018

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Genetic associations of T cell cancer immune response with tumor aggressiveness in localized prostate cancer patients and disease reclassification in an active surveillance cohort.
Qinchuan Wang, Justin R Gregg, Jian Gu, Yuanqing Ye, David W Chang, Timothy C Thompson

Oncoimmunology· October 2018

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