Publications by authors named "Timothy Clair"

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Phospholipase Cgamma activation drives increased production of autotaxin in endothelial cells and lysophosphatidic acid-dependent regression.
Eunok Im, Ruta Motiejunaite, Jorge Aranda, Eun Young Park, Lorenzo Federico, Timothy Clair

Mol Cell Biol· May 2010

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For science, no escape from politics.
Timothy Clair

Science· March 2009

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Novel point mutations attenuate autotaxin activity.
Eunjin Koh, Russell W Bandle, David D Roberts, Mary L Stracke, Timothy Clair

Lipids Health Dis· February 2009

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Regulation of lysophosphatidic acid receptor expression and function in human synoviocytes: implications for rheumatoid arthritis?
Chenqi Zhao, Maria J Fernandes, Glenn D Prestwich, Mélanie Turgeon, John Di Battista, Timothy Clair

Mol Pharmacol· February 2008

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Sphingosine-1-phosphate initiates rapid retraction of pseudopodia by localized RhoA activation.
Eunjin Koh, Timothy Clair, Raejean Hermansen, Russell W Bandle, Elliott Schiffmann

Cell Signal· June 2007

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Trichostatin A and 5-aza-2'-deoxycytidine switch S1P from an inhibitor to a stimulator of motility through epigenetic regulation of S1P receptors.
Eunjin Koh, Russell Bandle, Timothy Clair, David D Roberts, Mary L Stracke

Cancer Lett· May 2007

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The candidate tumor suppressor CST6 alters the gene expression profile of human breast carcinoma cells: down-regulation of the potent mitogenic, motogenic, and angiogenic factor autotaxin.
Jin Song, Chunfa Jie, Paula Polk, Ravi Shridhar, Timothy Clair

Biochem Biophys Res Commun· February 2006

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Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasion.
Hsin-Sheng Yang, Connie P Matthews, Timothy Clair, Qing Wang, Alyson R Baker

Mol Cell Biol· February 2006

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Autotaxin (lysoPLD/NPP2) protects fibroblasts from apoptosis through its enzymatic product, lysophosphatidic acid, utilizing albumin-bound substrate.
Jaehwi Song, Timothy Clair, Ji Heon Noh, Jung Woo Eun, So Yeon Ryu

Biochem Biophys Res Commun· November 2005

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Physiological mechanisms of tumor-cell invasion and migration.
David H Geho, Russell W Bandle, Timothy Clair, Lance A Liotta

Physiology (Bethesda)· June 2005

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L-histidine inhibits production of lysophosphatidic acid by the tumor-associated cytokine, autotaxin.
Timothy Clair, Eunjin Koh, Malgorzata Ptaszynska, Russell W Bandle, Lance A Liotta

Lipids Health Dis· February 2005

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Group A streptococcal vaccine delivery by immunization with a self-adjuvanting M protein-based lipid core peptide construct.
Colleen Olive, Michael Batzloff, Aniko Horváth, Timothy Clair, Penny Yarwood

Indian J Med Res· May 2004

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Microarray analysis identifies Autotaxin, a tumour cell motility and angiogenic factor with lysophospholipase D activity, as a specific target of cell transformation by v-Jun.
Elizabeth J Black, Timothy Clair, Jeffrey Delrow, Paul Neiman, David A F Gillespie

Oncogene· March 2004

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Autotaxin hydrolyzes sphingosylphosphorylcholine to produce the regulator of migration, sphingosine-1-phosphate.
Timothy Clair, Junken Aoki, Eunjin Koh, Russell W Bandle, Suk Woo Nam

Cancer Res· September 2003

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Hydrolysis of diadenosine polyphosphates by nucleotide pyrophosphatases/phosphodiesterases.
Petra Vollmayer, Timothy Clair, James W Goding, Kimihiko Sano, Jörg Servos

Eur J Biochem· July 2003

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Potential of lipid core peptide technology as a novel self-adjuvanting vaccine delivery system for multiple different synthetic peptide immunogens.
Colleen Olive, Michael Batzloff, Aniko Horváth, Timothy Clair, Penny Yarwood

Infect Immun· May 2003

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Site-directed mutations in the tumor-associated cytokine, autotaxin, eliminate nucleotide phosphodiesterase, lysophospholipase D, and motogenic activities.
Eunjin Koh, Timothy Clair, Elisa C Woodhouse, Elliott Schiffmann, Lance Liotta

Cancer Res· May 2003

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Analogous cytokine responses to Burkholderia pseudomallei strains contrasting in virulence correlate with partial cross-protection in immunized mice.
Glen C Ulett, Natkunam Ketheesan, Timothy W Clair, Catriona L McElnea, Jodie L Barnes

Infect Immun· July 2002

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Protection of mice from group A streptococcal infection by intranasal immunisation with a peptide vaccine that contains a conserved M protein B cell epitope and lacks a T cell autoepitope.
Colleen Olive, Timothy Clair, Penny Yarwood, Michael F Good

Vaccine· June 2002

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A lipid core peptide construct containing a conserved region determinant of the group A streptococcal M protein elicits heterologous opsonic antibodies.
Colleen Olive, Michael R Batzloff, Anikó Horváth, Allan Wong, Timothy Clair

Infect Immun· May 2002

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Lipoamino acid-based adjuvant carrier system: enhanced immunogenicity of group a streptococcal peptide epitopes.
Aniko Horvath, Colleen Olive, Allan Wong, Timothy Clair, Penny Yarwood

J Med Chem· March 2002

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