Publications by authors named "Timothy F Miles"

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Multimodal imaging of capsid and cargo reveals differential brain targeting and liver detargeting of systemically-administered AAVs.
Jai Woong Seo, Javier Ajenjo, Bo Wu, Elise Robinson, Marina Nura Raie, Timothy F Miles

Biomaterials· September 2022

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Structural basis of receptor usage by the engineered capsid AAV-PHP.eB.
Seongmin Jang, Hao K Shen, Xiaozhe Ding, Timothy F Miles, Viviana Gradinaru

Mol Ther Methods Clin Dev· September 2022

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Adeno-Associated Virus Toolkit to Target Diverse Brain Cells.
Rosemary C Challis, Sripriya Ravindra Kumar, Xinhong Chen, David Goertsen, Gerard M Coughlin, Timothy F Miles

Annu Rev Neurosci· July 2022

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Multiplexed Cre-dependent selection yields systemic AAVs for targeting distinct brain cell types.
Sripriya Ravindra Kumar, Timothy F Miles, Xinhong Chen, David Brown, Tatyana Dobreva

Nat Methods· May 2020

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Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy.
Timothy F Miles, Katja Spiess, Kevin M Jude, Naotaka Tsutsumi, John S Burg

Elife· June 2018

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Allosteric activation of the 5-HT3AB receptor by mCPBG.
Timothy F Miles, Henry A Lester, Dennis A Dougherty

Neuropharmacology· April 2015

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The 5-HT3AB receptor shows an A3B2 stoichiometry at the plasma membrane.
Timothy F Miles, Dennis A Dougherty, Henry A Lester

Biophys J· August 2013

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A coupled array of noncovalent interactions impacts the function of the 5-HT3A serotonin receptor in an agonist-specific way.
Timothy F Miles, Kiowa S Bower, Henry A Lester, Dennis A Dougherty

ACS Chem Neurosci· October 2012

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Polyglutamine fibrils are formed using a simple designed beta-hairpin model.
Melanie H Smith, Timothy F Miles, Molly Sheehan, Katherine N Alfieri, Bashkim Kokona

Proteins· June 2010

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