Publications by authors named "Timothy Fouts"

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Accelerated cGMP production of near-native HIV-1 Env trimers following electroporation transfection and immunogenicity analysis.
Shridhar Bale, Elena Gustchina, Javier Guenaga, Victor Ayala, Wen-Hsin Lee, Timothy Fouts

NPJ Vaccines· August 2025

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Safety and immunogenicity of an HIV-1 gp120-CD4 chimeric subunit vaccine in a phase 1a randomized controlled trial.
Joel V Chua, Charles Davis, Jennifer S Husson, Amy Nelson, Ilia Prado, Timothy Fouts

Vaccine· June 2021

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A single dose investigational subunit vaccine for human use against Nipah virus and Hendra virus.
Thomas W Geisbert, Kathryn Bobb, Viktoriya Borisevich, Joan B Geisbert, Krystle N Agans, Timothy R Fouts

NPJ Vaccines· February 2021

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Expression of CD40L by the ALVAC-Simian Immunodeficiency Virus Vector Abrogates T Cell Responses in Macaques.
Isabela Silva de Castro, Shari N Gordon, Jun Liu, Massimiliano Bissa, Katherine McKinnon, Timothy Fouts

J Virol· February 2020

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Antibody Fab-Fc properties outperform titer in predictive models of SIV vaccine-induced protection.
Srivamshi Pittala, Kenneth Bagley, Jennifer A Schwartz, Eric P Brown, Joshua A Weiner, Timothy R Fouts

Mol Syst Biol· May 2019

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Mucosal vaccine efficacy against intrarectal SHIV is independent of anti-Env antibody response.
Yongjun Sui, George K Lewis, Yichuan Wang, Kurt Berckmueller, Blake Frey, Timothy Fouts

J Clin Invest· March 2019

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Expression of Human Immunodeficiency Virus Type 1 Neutralizing Antibody Fragments Using Human Vaginal Lactobacillus.
Angela Marcobal, Xiaowen Liu, Wenlei Zhang, Antony S Dimitrov, Letong Jia, Timothy R Fouts

AIDS Res Hum Retroviruses· December 2017

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An Interleukin 12 Adjuvanted Herpes Simplex Virus 2 DNA Vaccine Is More Protective Than a Glycoprotein D Subunit Vaccine in a High-Dose Murine Challenge Model.
Kenneth C Bagley, Jennifer A Schwartz, Hanne Andersen, John H Eldridge, Rong Xu, Timothy R Fouts

Viral Immunol· April 2017

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Adsorption of a synthetic TLR7/8 ligand to aluminum oxyhydroxide for enhanced vaccine adjuvant activity: A formulation approach.
Christopher B Fox, Mark T Orr, Neal Van Hoeven, Sarah C Parker, Traci J T Mikasa, Timothy R Fouts

J Control Release· December 2016

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Retinaldehyde dehydrogenase 2 as a molecular adjuvant for enhancement of mucosal immunity during DNA vaccination.
Susan A Holechek, Megan S McAfee, Lizbeth M Nieves, Vanessa P Guzman, Kavita Manhas, Timothy Fouts

Vaccine· November 2016

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Boosting of ALVAC-SIV Vaccine-Primed Macaques with the CD4-SIVgp120 Fusion Protein Elicits Antibodies to V2 Associated with a Decreased Risk of SIVmac251 Acquisition.
Shari N Gordon, Namal P M Liyanage, Melvin N Doster, Monica Vaccari, Diego A Vargas-Inchaustegui, Timothy Fouts

J Immunol· October 2016

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Synergistic Inhibition of R5 HIV-1 by the Fusion Protein (FLSC) IgG1 Fc and Maraviroc in Primary Cells: Implications for Prevention and Treatment.
Olga S Latinovic, Jian Zhang, Yutaka Tagaya, Anthony L DeVico, Timothy R Fouts

Curr HIV Res· August 2016

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An HIV gp120-CD4 Immunogen Does Not Elicit Autoimmune Antibody Responses in Cynomolgus Macaques.
Jennifer A Schwartz, Ilia Prado, Johnathan Misamore, Deborah Weiss, Jesse Francis, Timothy R Fouts

Clin Vaccine Immunol· July 2016

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The catalytic A1 domains of cholera toxin and heat-labile enterotoxin are potent DNA adjuvants that evoke mixed Th1/Th17 cellular immune responses.
Kenneth Bagley, Rong Xu, Ayuko Ota-Setlik, Michael Egan, Jennifer Schwartz, Timothy Fouts

Hum Vaccin Immunother· May 2016

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Paring Down HIV Env: Design and Crystal Structure of a Stabilized Inner Domain of HIV-1 gp120 Displaying a Major ADCC Target of the A32 Region.
William D Tolbert, Neelakshi Gohain, Maxime Veillette, Jean-Philippe Chapleau, Chiara Orlandi, Timothy R Fouts

Structure· May 2016

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NF-κB-activating complex engaged in response to EGFR oncogene inhibition drives tumor cell survival and residual disease in lung cancer.
Collin M Blakely, Evangelos Pazarentzos, Victor Olivas, Saurabh Asthana, Jenny Jiacheng Yan, Timothy R Fouts

Cell Rep· April 2015

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Balance of cellular and humoral immunity determines the level of protection by HIV vaccines in rhesus macaque models of HIV infection.
Timothy R Fouts, Kenneth Bagley, Ilia J Prado, Kathryn L Bobb, Jennifer A Schwartz

Proc Natl Acad Sci U S A· March 2015

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HIV-1 CD4-induced (CD4i) gp120 epitope vaccines promote B and T-cell responses that contribute to reduced viral loads in rhesus macaques.
Michael A Thomas, Iskra Tuero, Thorsten Demberg, Diego A Vargas-Inchaustegui, Thomas Musich, Timothy Fouts

Virology· December 2014

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Diverse specificity and effector function among human antibodies to HIV-1 envelope glycoprotein epitopes exposed by CD4 binding.
Yongjun Guan, Marzena Pazgier, Mohammad M Sajadi, Roberta Kamin-Lewis, Salma Al-Darmarki, Timothy R Fouts

Proc Natl Acad Sci U S A· January 2013

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Identification and characterization of an immunogenic hybrid epitope formed by both HIV gp120 and human CD4 proteins.
George K Lewis, Timothy R Fouts, Sani Ibrahim, Brian M Taylor, Rachita Salkar

J Virol· December 2011

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Adjuvant activity of the catalytic A1 domain of cholera toxin for retroviral antigens delivered by GeneGun.
Kenneth C Bagley, George K Lewis, Timothy R Fouts

Clin Vaccine Immunol· June 2011

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Potent and broad neutralizing activity of a single chain antibody fragment against cell-free and cell-associated HIV-1.
Mei-Yun Zhang, Andrew Rosa Borges, Roger G Ptak, Yanping Wang, Antony S Dimitrov, Timothy Fouts

MAbs· December 2010

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Neutralization of HIV by antibodies.
Ilia Prado, Timothy R Fouts, Antony S Dimitrov

Methods Mol Biol· April 2009

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Discordant memory B cell and circulating anti-Env antibody responses in HIV-1 infection.
Yongjun Guan, Mohammad M Sajadi, Roberta Kamin-Lewis, Timothy R Fouts, Anthony Dimitrov

Proc Natl Acad Sci U S A· March 2009

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Antibodies to CD4-induced sites in HIV gp120 correlate with the control of SHIV challenge in macaques vaccinated with subunit immunogens.
Anthony DeVico, Timothy Fouts, George K Lewis, Robert C Gallo, Karla Godfrey

Proc Natl Acad Sci U S A· October 2007

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