Publications by authors named "Timothy J Chambers"

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Erratum to 'Cathepsin K inhibitors prevent matrix-derived growth factor degradation by human osteoclasts'.
Karen Fuller, Kevin M Lawrence, Jade L Ross, Urszula B Grabowska, Masahiro Shiroo, Timothy J Chambers

Bone· April 2021

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Urocortin is a novel regulator of osteoclast differentiation and function through inhibition of a canonical transient receptor potential 1-like cation channel.
Charlotte E Combs, Karen Fuller, Hashethra Kumar, Anthony P Albert, Grisha Pirianov, Timothy J Chambers

J Endocrinol· February 2012

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The resorptive apparatus of osteoclasts supports lysosomotropism and increases potency of basic versus non-basic inhibitors of cathepsin K.
Karen Fuller, Erik Lindstrom, Michael Edlund, Ian Henderson, Urszula Grabowska, Timothy J Chambers

Bone· May 2010

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Cathepsin K inhibitors prevent matrix-derived growth factor degradation by human osteoclasts.
Karen Fuller, Kevin M Lawrence, Jade L Ross, Urszula B Grabowska, Masahiro Shiroo, Timothy J Chambers

Bone· January 2008

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Regulation and enzymatic basis of bone resorption by human osteoclasts.
Karen Fuller, Barrie Kirstein, Timothy J Chambers

Clin Sci (Lond)· June 2007

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A novel assay for analysis of the regulation of the function of human osteoclasts.
Barrie Kirstein, Urszula Grabowska, Bertil Samuelsson, Masahiro Shiroo, Timothy J Chambers

J Transl Med· November 2006

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Secretion of tartrate-resistant acid phosphatase by osteoclasts correlates with resorptive behavior.
Barrie Kirstein, Timothy J Chambers, Karen Fuller

J Cell Biochem· August 2006

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The effect of oestrogen on megakaryocyte differentiation and platelet counts in vivo.
Simon W Fox, Timothy J Chambers

Int J Cardiol· May 2006

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Murine osteoclast formation and function: differential regulation by humoral agents.
Karen Fuller, Barrie Kirstein, Timothy J Chambers

Endocrinology· April 2006

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Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.
James G Conway, Brad McDonald, Janet Parham, Barry Keith, David W Rusnak, Timothy J Chambers

Proc Natl Acad Sci U S A· November 2005

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Recent developments in cathepsin K inhibitor design.
Urszula Grabowskal, Timothy J Chambers, Masahiro Shiroo

Curr Opin Drug Discov Devel· September 2005

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Hydrogen peroxide is essential for estrogen-deficiency bone loss and osteoclast formation.
Jenny M Lean, Chris J Jagger, Barrie Kirstein, Karen Fuller, Timothy J Chambers

Endocrinology· February 2005

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TGF-beta-induced SOCS3 expression augments TNF-alpha-induced osteoclast formation.
Alison C Lovibond, S Jaharul Haque, Timothy J Chambers, Simon W Fox

Biochem Biophys Res Commun· October 2003

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A crucial role for thiol antioxidants in estrogen-deficiency bone loss.
Jenny M Lean, Julie T Davies, Karen Fuller, Christopher J Jagger, Barrie Kirstein, Timothy J Chambers

J Clin Invest· September 2003

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CCL9/MIP-1gamma and its receptor CCR1 are the major chemokine ligand/receptor species expressed by osteoclasts.
Jenny M Lean, Chiho Murphy, Karen Fuller, Timothy J Chambers

J Cell Biochem· June 2003

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The possible role of TGF-beta-induced suppressors of cytokine signaling expression in osteoclast/macrophage lineage commitment in vitro.
Simon W Fox, S Jaharul Haque, Alison C Lovibond, Timothy J Chambers

J Immunol· April 2003

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TNFalpha potently activates osteoclasts, through a direct action independent of and strongly synergistic with RANKL.
Karen Fuller, Chiho Murphy, Barrie Kirstein, Simon W Fox, Timothy J Chambers

Endocrinology· March 2002

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