Publications by authors named "Timothy Kurt"

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Mutant prion protein enhances NMDA receptor activity, activates PKC, and triggers rapid excitotoxicity in mice.
Joie Lin, Julia A Callender, Joshua E Mayfield, Daniel B McClatchy, Daniel Ojeda-Juárez, Timothy D Kurt

J Clin Invest· May 2025

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Scaling analysis reveals the mechanism and rates of prion replication in vivo.
Georg Meisl, Timothy Kurt, Itzel Condado-Morales, Cyrus Bett, Silvia Sorce

Nat Struct Mol Biol· April 2021

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Key Considerations for the Use of Seaweed to Reduce Enteric Methane Emissions From Cattle.
Sandra Vijn, Devan Paulus Compart, Nikki Dutta, Athanasios Foukis, Matthias Hess, Timothy D Kurt

Front Vet Sci· December 2020

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Prion protein post-translational modifications modulate heparan sulfate binding and limit aggregate size in prion disease.
Julia A Callender, Alejandro M Sevillano, Katrin Soldau, Timothy D Kurt, Taylor Schumann

Neurobiol Dis· August 2020

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Prion protein glycans reduce intracerebral fibril formation and spongiosis in prion disease.
Alejandro M Sevillano, Patricia Aguilar-Calvo, Timothy D Kurt, Jessica A Lawrence, Katrin Soldau

J Clin Invest· March 2020

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Strategic Priorities for Research on Antibiotic Alternatives in Animal Agriculture-Results From an Expert Workshop.
Timothy Kurt, Nora Wong, Heather Fowler, Cyril Gay, Hyun Lillehoj

Front Vet Sci· November 2019

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Generation of novel neuroinvasive prions following intravenous challenge.
Patricia Aguilar-Calvo, Cyrus Bett, Alejandro M Sevillano, Timothy D Kurt, Jessica Lawrence

Brain Pathol· November 2018

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Asparagine and glutamine ladders promote cross-species prion conversion.
Timothy D Kurt, Patricia Aguilar-Calvo, Lin Jiang, José A Rodriguez, Nazilla Alderson

J Biol Chem· November 2017

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Enhanced neuroinvasion by smaller, soluble prions.
Cyrus Bett, Jessica Lawrence, Timothy D Kurt, Christina Orru, Patricia Aguilar-Calvo

Acta Neuropathol Commun· April 2017

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Cross-species transmission of CWD prions.
Timothy D Kurt, Christina J Sigurdson

Prion· January 2017

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Multiple Mechanisms of Unfolded Protein Response-Induced Cell Death.
Nobuhiko Hiramatsu, Wei-Chieh Chiang, Timothy D Kurt, Christina J Sigurdson, Jonathan H Lin

Am J Pathol· July 2015

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Human prion protein sequence elements impede cross-species chronic wasting disease transmission.
Timothy D Kurt, Lin Jiang, Natalia Fernández-Borges, Cyrus Bett, Jun Liu

J Clin Invest· June 2015

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Human prion protein sequence elements impede cross-species chronic wasting disease transmission.
Timothy D Kurt, Lin Jiang, Natalia Fernández-Borges, Cyrus Bett, Jun Liu

J Clin Invest· April 2015

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A proposed mechanism for the promotion of prion conversion involving a strictly conserved tyrosine residue in the β2-α2 loop of PrPC.
Timothy D Kurt, Lin Jiang, Cyrus Bett, David Eisenberg, Christina J Sigurdson

J Biol Chem· April 2014

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Prion transmission prevented by modifying the β2-α2 loop structure of host PrPC.
Timothy D Kurt, Cyrus Bett, Natalia Fernández-Borges, Shivanjali Joshi-Barr, Simone Hornemann, Kurt Wüthrich

J Neurosci· January 2014

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Structure of the β2-α2 loop and interspecies prion transmission.
Cyrus Bett, Natalia Fernández-Borges, Timothy D Kurt, Melanie Lucero, K Peter R Nilsson

FASEB J· July 2012

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Alteration of the chronic wasting disease species barrier by in vitro prion amplification.
Timothy D Kurt, Davis M Seelig, Jay R Schneider, Christopher J Johnson, Glenn C Telling

J Virol· September 2011

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Trans-species amplification of PrP(CWD) and correlation with rigid loop 170N.
Timothy D Kurt, Glenn C Telling, Mark D Zabel, Edward A Hoover

Virology· April 2009

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In vitro strain adaptation of CWD prions by serial protein misfolding cyclic amplification.
Crystal Meyerett, Brady Michel, Bruce Pulford, Terry R Spraker, Traci A Nichols, Timothy Kurt

Virology· December 2008

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Efficient in vitro amplification of chronic wasting disease PrPRES.
Timothy D Kurt, Matthew R Perrott, Carol J Wilusz, Jeffrey Wilusz, Surachai Supattapone

J Virol· September 2007

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