Publications by authors named "Timothy L Chen"

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Azacitidine, Venetoclax, and Revumenib for Newly Diagnosed -Mutated or -Rearranged AML.
Joshua F Zeidner, Tara L Lin, Rina Li Welkie, Emily Curran, Kristin Koenig, Timothy L Chen

J Clin Oncol· August 2025

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A Phase 1b/2 Study of TP-0903 and Decitabine Targeting Mutant TP53 and/or Complex Karyotype in Patients with Untreated Acute Myeloid Leukemia ≥Age 60 Years.
Eric D Eisenmann, Ronan Swords, Ying Huang, Shelley Orwick, Daelynn Buelow, Timothy L Chen

Cancer Res Commun· July 2025

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A study to assess the efficacy of enasidenib and risk-adapted addition of azacitidine in newly diagnosed IDH2-mutant AML.
Sheng F Cai, Ying Huang, Jennie R Lance, Hsiaoyin Charlene Mao, Andrew J Dunbar, Timothy L Chen

Blood Adv· January 2024

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Application of a Domain-specific BERT for Detection of Speech Recognition Errors in Radiology Reports.
Gunvant R Chaudhari, Tengxiao Liu, Timothy L Chen, Gabby B Joseph, Maya Vella

Radiol Artif Intell· July 2022

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Clinical language search algorithm from free-text: facilitating appropriate imaging.
Gunvant R Chaudhari, Yeshwant R Chillakuru, Timothy L Chen, Valentina Pedoia, Thienkhai H Vu

BMC Med Imaging· February 2022

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Development and web deployment of an automated neuroradiology MRI protocoling tool with natural language processing.
Yeshwant Reddy Chillakuru, Shourya Munjal, Benjamin Laguna, Timothy L Chen, Gunvant R Chaudhari

BMC Med Inform Decis Mak· July 2021

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Preclinical evaluation of the Hsp90 inhibitor SNX-5422 in ibrutinib resistant CLL.
Timothy L Chen, Bonnie Harrington, Jean Truxall, Ronni Wasmuth, Alexander Prouty

J Hematol Oncol· February 2021

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Domain specific word embeddings for natural language processing in radiology.
Timothy L Chen, Max Emerling, Gunvant R Chaudhari, Yeshwant R Chillakuru, Youngho Seo

J Biomed Inform· January 2021

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Targeting the C481S Ibrutinib-Resistance Mutation in Bruton's Tyrosine Kinase Using PROTAC-Mediated Degradation.
Alexandru D Buhimschi, Haley A Armstrong, Momar Toure, Saul Jaime-Figueroa, Timothy L Chen

Biochemistry· July 2018

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NF-κB p50 () contributes to pathogenesis in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia.
Timothy L Chen, Minh Tran, Aparna Lakshmanan, Bonnie K Harrington, Nikhil Gupta

Blood· July 2017

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The long noncoding RNA, treRNA, decreases DNA damage and is associated with poor response to chemotherapy in chronic lymphocytic leukemia.
Cecelia R Miller, Amy S Ruppert, Sydney Fobare, Timothy L Chen, Chaomei Liu

Oncotarget· April 2017

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A phase I trial of the intravenous Hsp90 inhibitor alvespimycin (17-DMAG) in patients with relapsed chronic lymphocytic leukemia/small lymphocytic lymphoma.
Kami Maddocks, Erin Hertlein, Timothy L Chen, Amy J Wagner, Yonghua Ling

Leuk Lymphoma· September 2016

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Hsp90 inhibition increases SOCS3 transcript and regulates migration and cell death in chronic lymphocytic leukemia.
Timothy L Chen, Nikhil Gupta, Amy Lehman, Amy S Ruppert, Lianbo Yu

Oncotarget· May 2016

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Characterization of a new chronic lymphocytic leukemia cell line for mechanistic in vitro and in vivo studies relevant to disease.
Erin Hertlein, Kyle A Beckwith, Gerard Lozanski, Timothy L Chen, William H Towns

PLoS One· June 2014

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The proteasome inhibitor carfilzomib functions independently of p53 to induce cytotoxicity and an atypical NF-κB response in chronic lymphocytic leukemia cells.
Sneha V Gupta, Erin Hertlein, Yanhui Lu, Ellen J Sass, Rosa Lapalombella, Timothy L Chen

Clin Cancer Res· May 2013

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