Publications by authors named "Timothy Oriss"

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Corrigendum to High IFN-γ and low SLPI mark severe asthma in mice and humans.
Mahesh Raundhal, Christina Morse, Anupriya Khare, Timothy B Oriss, Jadranka Milosevic

J Clin Invest· July 2025

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CD8+ TEMRAs in severe asthma associate with asthma symptom duration and escape proliferation arrest.
Richard P Ramonell, Timothy B Oriss, Jessica C McCreary-Partyka, Sagar L Kale, Nicole R Brandon

JCI Insight· April 2025

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Antigen-driven T cell-macrophage interactions mediate the interface between innate and adaptive immunity in histidyl-tRNA synthetase-induced myositis.
Daniel P Reay, Tracy Tabib, Ying Wang, Timothy B Oriss, Nicholas A Young

Front Immunol· November 2023

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CCL5 is a potential bridge between type 1 and type 2 inflammation in asthma.
Marc Gauthier, Sagar Laxman Kale, Timothy B Oriss, Michael Gorry, Richard P Ramonell

J Allergy Clin Immunol· July 2023

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Dual role for CXCR3 and CCR5 in asthmatic type 1 inflammation.
Marc Gauthier, Sagar Laxman Kale, Timothy B Oriss, Kathryn Scholl, Sudipta Das

J Allergy Clin Immunol· January 2022

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Early life exposure to house dust mite allergen prevents experimental allergic asthma requiring mitochondrial HO.
Huijuan Yuan, Jie Chen, Sanmei Hu, Timothy B Oriss, Sagar Laxman Kale

Mucosal Immunol· January 2022

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Immune responses and exacerbations in severe asthma.
Matthew J Camiolo, Sagar L Kale, Timothy B Oriss, Marc Gauthier, Anuradha Ray

Curr Opin Immunol· October 2021

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High-dimensional profiling clusters asthma severity by lymphoid and non-lymphoid status.
Matthew J Camiolo, Xiaoying Zhou, Timothy B Oriss, Qi Yan, Michael Gorry

Cell Rep· April 2021

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mTOR regulates metabolic adaptation of APCs in the lung and controls the outcome of allergic inflammation.
Charles Sinclair, Gayathri Bommakanti, Luiz Gardinassi, Jens Loebbermann, Matthew Joseph Johnson, Timothy Oriss

Science· September 2017

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Respiratory syncytial virus infection of newborn CX3CR1-deficient mice induces a pathogenic pulmonary innate immune response.
Sudipta Das, Mahesh Raundhal, Jie Chen, Timothy B Oriss, Rachael Huff

JCI Insight· September 2017

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Severe asthma in humans and mouse model suggests a CXCL10 signature underlies corticosteroid-resistant Th1 bias.
Marc Gauthier, Krishnendu Chakraborty, Timothy B Oriss, Mahesh Raundhal, Sudipta Das

JCI Insight· July 2017

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IRF5 distinguishes severe asthma in humans and drives Th1 phenotype and airway hyperreactivity in mice.
Timothy B Oriss, Mahesh Raundhal, Christina Morse, Rachael E Huff, Sudipta Das

JCI Insight· May 2017

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The mito-DAMP cardiolipin blocks IL-10 production causing persistent inflammation during bacterial pneumonia.
Krishnendu Chakraborty, Mahesh Raundhal, Bill B Chen, Christina Morse, Yulia Y Tyurina, Timothy B Oriss

Nat Commun· January 2017

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Current concepts of severe asthma.
Anuradha Ray, Mahesh Raundhal, Timothy B Oriss, Prabir Ray, Sally E Wenzel

J Clin Invest· July 2016

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Mitochondrial H2O2 in Lung Antigen-Presenting Cells Blocks NF-κB Activation to Prevent Unwarranted Immune Activation.
Anupriya Khare, Mahesh Raundhal, Krishnendu Chakraborty, Sudipta Das, Catherine Corey, Timothy B Oriss

Cell Rep· May 2016

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High IFN-γ and low SLPI mark severe asthma in mice and humans.
Mahesh Raundhal, Christina Morse, Anupriya Khare, Timothy B Oriss, Jadranka Milosevic

J Clin Invest· August 2015

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Emerging molecular phenotypes of asthma.
Anuradha Ray, Timothy B Oriss, Sally E Wenzel

Am J Physiol Lung Cell Mol Physiol· January 2015

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Cutting Edge: MMP-9 inhibits IL-23p19 expression in dendritic cells by targeting membrane stem cell factor affecting lung IL-17 response.
Timothy B Oriss, Nandini Krishnamoorthy, Mahesh Raundhal, Christina Morse, Krishnendu Chakraborty

J Immunol· June 2014

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Dendritic cell c-kit signaling and adaptive immunity: implications for the upper airways.
Timothy B Oriss, Nandini Krishnamoorthy, Prabir Ray, Anuradha Ray

Curr Opin Allergy Clin Immunol· February 2014

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Cutting edge: inhaled antigen upregulates retinaldehyde dehydrogenase in lung CD103+ but not plasmacytoid dendritic cells to induce Foxp3 de novo in CD4+ T cells and promote airway tolerance.
Anupriya Khare, Nandini Krishnamoorthy, Timothy B Oriss, Mingjian Fei, Prabir Ray

J Immunol· July 2013

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The relationship between the severity of hemolysis, clinical manifestations and risk of death in 415 patients with sickle cell anemia in the US and Europe.
Mehdi Nouraie, Janet S Lee, Yingze Zhang, Tamir Kanias, Xuejun Zhao, Timothy B Oriss

Haematologica· March 2013

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Early infection with respiratory syncytial virus impairs regulatory T cell function and increases susceptibility to allergic asthma.
Nandini Krishnamoorthy, Anupriya Khare, Timothy B Oriss, Mahesh Raundhal, Christina Morse

Nat Med· October 2012

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TNF-alpha from inflammatory dendritic cells (DCs) regulates lung IL-17A/IL-5 levels and neutrophilia versus eosinophilia during persistent fungal infection.
Mingjian Fei, Shikha Bhatia, Timothy B Oriss, Manohar Yarlagadda, Anupriya Khare

Proc Natl Acad Sci U S A· March 2011

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Macrophages: regulators of sex differences in asthma?
Barbro N Melgert, Timothy B Oriss, Zengbiao Qi, Barbara Dixon-McCarthy, Marie Geerlings

Am J Respir Cell Mol Biol· May 2010

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Signaling of c-kit in dendritic cells influences adaptive immunity.
Prabir Ray, Nandini Krishnamoorthy, Timothy B Oriss, Anuradha Ray

Ann N Y Acad Sci· January 2010

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