Publications by authors named "Timothy Pruess"

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Spontaneous recurrent seizures in an intra-amygdala kainate microinjection model of temporal lobe epilepsy are differentially sensitive to antiseizure drugs.
Peter J West, Kyle Thomson, Peggy Billingsley, Timothy Pruess, Carlos Rueda

Exp Neurol· March 2022

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Validation of a Preclinical Drug Screening Platform for Pharmacoresistant Epilepsy.
Melissa L Barker-Haliski, Kristina Johnson, Peggy Billingsley, Jennifer Huff, Laura J Handy, Timothy H Pruess

Neurochem Res· July 2017

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Preclinical Comparison of Mechanistically Different Antiseizure, Antinociceptive, and/or Antidepressant Drugs in a Battery of Rodent Models of Nociceptive and Neuropathic Pain.
Misty D Smith, Jose H Woodhead, Laura J Handy, Timothy H Pruess, Fabiola Vanegas

Neurochem Res· July 2017

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Acute treatment with minocycline, but not valproic acid, improves long-term behavioral outcomes in the Theiler's virus model of temporal lobe epilepsy.
Melissa L Barker-Haliski, Taylor D Heck, E Jill Dahle, Fabiola Vanegas, Timothy H Pruess

Epilepsia· December 2016

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Evaluating an etiologically relevant platform for therapy development for temporal lobe epilepsy: effects of carbamazepine and valproic acid on acute seizures and chronic behavioral comorbidities in the Theiler's murine encephalomyelitis virus mouse model.
Melissa L Barker-Haliski, E Jill Dahle, Taylor D Heck, Timothy H Pruess, Fabiola Vanegas

J Pharmacol Exp Ther· May 2015

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Generating orally active galanin analogues with analgesic activities.
Charles R Robertson, Timothy H Pruess, Erin Grussendorf, H Steve White, Grzegorz Bulaj

ChemMedChem· May 2012

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Introduction of lipidization-cationization motifs affords systemically bioavailable neuropeptide Y and neurotensin analogs with anticonvulsant activities.
Brad R Green, Karen L White, Daniel R McDougle, Liuyin Zhang, Brian Klein, Timothy H Pruess

J Pept Sci· September 2010

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Engineering galanin analogues that discriminate between GalR1 and GalR2 receptor subtypes and exhibit anticonvulsant activity following systemic delivery.
Charles R Robertson, Erika Adkins Scholl, Timothy H Pruess, Brad R Green, H Steve White

J Med Chem· February 2010

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A role of SCN9A in human epilepsies, as a cause of febrile seizures and as a potential modifier of Dravet syndrome.
Nanda A Singh, Chris Pappas, E Jill Dahle, Lieve R F Claes, Timothy H Pruess

PLoS Genet· September 2009

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Electroconvulsive seizure thresholds and kindling acquisition rates are altered in mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions.
James F Otto, Nanda A Singh, E Jill Dahle, Mark F Leppert, Chris M Pappas, Timothy H Pruess

Epilepsia· July 2009

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Developing novel antiepileptic drugs: characterization of NAX 5055, a systemically-active galanin analog, in epilepsy models.
H Steve White, Erika A Scholl, Brian D Klein, Sean P Flynn, Timothy H Pruess

Neurotherapeutics· April 2009

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Structural requirements for a lipoamino acid in modulating the anticonvulsant activities of systemically active galanin analogues.
Liuyin Zhang, Charles R Robertson, Brad R Green, Timothy H Pruess, H Steve White

J Med Chem· March 2009

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Synthesis and applications of polyamine amino acid residues: improving the bioactivity of an analgesic neuropeptide, neurotensin.
Liuyin Zhang, Hee-Kyoung Lee, Timothy H Pruess, H Steve White, Grzegorz Bulaj

J Med Chem· March 2009

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Design, synthesis, and characterization of high-affinity, systemically-active galanin analogues with potent anticonvulsant activities.
Grzegorz Bulaj, Brad R Green, Hee-Kyoung Lee, Charles R Robertson, Karen White, Timothy H Pruess

J Med Chem· December 2008

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