Publications by authors named "Timothy R Radstake"

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Discovery of new myositis genetic associations through leveraging other immune-mediated diseases.
Guillermo Reales, Christopher I Amos, Olivier Benveniste, Hector Chinoy, Jan De Bleecker, Timothy R Radstake

HGG Adv· October 2024

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Leflunomide/hydroxychloroquine combination therapy targets type I IFN-associated proteins in patients with Sjögren's syndrome that show potential to predict and monitor clinical response.
Safae Hamkour, Eefje Hm van der Heijden, Ana P Lopes, Sofie L M Blokland, Cornelis P J Bekker, Timothy Rdj Radstake

RMD Open· August 2023

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Deciphering the role of cDC2s in Sjögren's syndrome: transcriptomic profile links altered antigen processes with IFN signature and autoimmunity.
Ana P Lopes, Maarten R Hillen, Anneline C Hinrichs, Sofie Lm Blokland, Cornelis Pj Bekker, Timothy Rdj Radstake

Ann Rheum Dis· March 2023

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Comprehensive analysis of the major histocompatibility complex in systemic sclerosis identifies differential HLA associations by clinical and serological subtypes.
Marialbert Acosta-Herrera, Martin Kerick, Elena Lopéz-Isac, Shervin Assassi, Lorenzo Beretta, Timothy Rdj Radstake

Ann Rheum Dis· August 2021

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Tissue-Resident Memory CD8+ T Cells From Skin Differentiate Psoriatic Arthritis From Psoriasis.
Emmerik F Leijten, Tessa S van Kempen, Michel A Olde Nordkamp, Juliette N Pouw, Nienke J Kleinrensink, Timothy R Radstake

Arthritis Rheumatol· July 2021

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Genomic Risk Score impact on susceptibility to systemic sclerosis.
Lara Bossini-Castillo, Gonzalo Villanueva-Martin, Martin Kerick, Marialbert Acosta-Herrera, Elena López-Isac, Timothy Rdj Radstake

Ann Rheum Dis· January 2021

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Neutrophil extracellular traps and low-density granulocytes are associated with the interferon signature in systemic lupus erythematosus, but not in antiphospholipid syndrome.
Lucas L van den Hoogen, Maarten van der Linden, Linde Meyaard, Ruth D E Fritsch-Stork, Joel A van Roon, Timothy Rdj Radstake

Ann Rheum Dis· October 2020

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Extracellular SPARC cooperates with TGF-β signalling to induce pro-fibrotic activation of systemic sclerosis patient dermal fibroblasts.
Tiago Carvalheiro, Beatriz Malvar Fernández, Andrea Ottria, Barbara Giovannone, Wioleta Marut, Timothy R Radstake

Rheumatology (Oxford)· September 2020

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Promotion of macrophage activation by Tie2 in the context of the inflamed synovia of rheumatoid arthritis and psoriatic arthritis patients.
Pawel A Kabala, Beatriz Malvar-Fernández, Ana P Lopes, Tiago Carvalheiro, Sarita A Y Hartgring, Timothy R Radstake

Rheumatology (Oxford)· February 2020

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Induction of Inflammation and Fibrosis by Semaphorin 4A in Systemic Sclerosis.
Tiago Carvalheiro, Alsya J Affandi, Beatriz Malvar-Fernández, Ilse Dullemond, Marta Cossu, Timothy R Radstake

Arthritis Rheumatol· October 2019

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Low RUNX3 expression alters dendritic cell function in patients with systemic sclerosis and contributes to enhanced fibrosis.
Alsya J Affandi, Tiago Carvalheiro, Andrea Ottria, Jasper Ca Broen, Lara Bossini-Castillo, Timothy Rdj Radstake

Ann Rheum Dis· September 2019

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Additive immunosuppressive effect of leflunomide and hydroxychloroquine supports rationale for combination therapy for Sjögren's syndrome.
Eefje Hm van der Heijden, Sarita Ay Hartgring, Aike A Kruize, Timothy Rdj Radstake, Joel Ag van Roon

Expert Rev Clin Immunol· July 2019

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Limits of traditional evidence-based medicine methodologies exemplified by the novel era in psoriatic arthritis drug development.
Emmerik F Leijten, Timothy R Radstake, Iain B McInnes, Johannes W Jacobs

Expert Rev Clin Immunol· May 2019

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RNA sequencing to predict response to TNF-α inhibitors reveals possible mechanism for nonresponse in smokers.
Bart V J Cuppen, Marzia Rossato, Ruth D E Fritsch-Stork, Arno N Concepcion, Suzanne P Linn-Rasker, Timothy R Radstake

Expert Rev Clin Immunol· July 2018

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Endoplasmic reticulum stress cooperates with Toll-like receptor ligation in driving activation of rheumatoid arthritis fibroblast-like synoviocytes.
Pawel A Kabala, Chiara Angiolilli, Nataliya Yeremenko, Aleksander M Grabiec, Barbara Giovannone, Timothy R Radstake

Arthritis Res Ther· September 2017

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Standardisation of labial salivary gland histopathology in clinical trials in primary Sjögren's syndrome.
Benjamin A Fisher, Roland Jonsson, Troy Daniels, Michele Bombardieri, Rachel M Brown, Timothy R Radstake

Ann Rheum Dis· July 2017

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The acetyl code in rheumatoid arthritis and other rheumatic diseases.
Chiara Angiolilli, Dominique L Baeten, Timothy R Radstake, Kris A Reedquist

Epigenomics· April 2017

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Hematopoietic stem cell-derived myeloid and plasmacytoid DC-based vaccines are highly potent inducers of tumor-reactive T cell and NK cell responses .
Soley Thordardottir, Nicolaas Schaap, Elja Louer, Michel G D Kester, J H Frederik Falkenburg, Timothy R D Radstake

Oncoimmunology· February 2017

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Size matters: decreased glandular levels of anti-inflammatory short thymic stromal lymphopoietin in primary Sjögren's syndrome.
Maarten R Hillen, Frederique M Moret, Barbara Giovannone, Aike A Kruize, Timothy R D J Radstake

Clin Exp Rheumatol· January 2017

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Is sex bias orchestrated in the skin?
Aridaman Pandit, Linde Meyaard, Timothy R D J Radstake

Nat Immunol· January 2017

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The magnitude of cytokine production by stimulated CD56 cells is associated with early stages of systemic sclerosis.
Marta Cossu, Lenny van Bon, Stefan Nierkens, Chiara Bellocchi, Alessandro Santaniello, Timothy R D J Radstake

Clin Immunol· December 2016

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Monocyte type I interferon signature in antiphospholipid syndrome is related to proinflammatory monocyte subsets, hydroxychloroquine and statin use.
Lucas L van den Hoogen, Ruth D E Fritsch-Stork, Marjan A Versnel, Ronald H Wm Derksen, Joël A G van Roon, Timothy R Dj Radstake

Ann Rheum Dis· December 2016

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High-Dose Intravenous Pulse Methotrexate in Patients With Eosinophilic Fasciitis.
Jorre S Mertens, Manon C Zweers, Wietske Kievit, Hanneke K A Knaapen, Martijn Gerritsen, Timothy R D J Radstake

JAMA Dermatol· November 2016

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Immune checkpoints and rheumatic diseases: what can cancer immunotherapy teach us?
Michiel van der Vlist, Jurgen Kuball, Timothy R D Radstake, Linde Meyaard

Nat Rev Rheumatol· October 2016

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Can baseline serum microRNAs predict response to TNF-alpha inhibitors in rheumatoid arthritis?
Bart V J Cuppen, Marzia Rossato, Ruth D E Fritsch-Stork, Arno N Concepcion, Yolande Schenk, Timothy R D J Radstake

Arthritis Res Ther· August 2016

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