Publications by authors named "Timothy Thornton"

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Multiple-testing corrections in case-control studies using identity-by-descent segments.
Seth D Temple, Nicola H Chapman, Seung Hoan Choi, Anita L DeStefano, Timothy A Thornton

bioRxiv· July 2025

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Author Correction: A deep catalogue of protein-coding variation in 983,578 individuals.
Kathie Y Sun, Xiaodong Bai, Siying Chen, Suying Bao, Chuanyi Zhang, Timothy Thornton

Nature· January 2025

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General Kernel Machine Methods for Multi-Omics Integration and Genome-Wide Association Testing With Related Individuals.
Amarise Little, Ni Zhao, Anna Mikhaylova, Angela Zhang, Wodan Ling, Timothy Thornton

Genet Epidemiol· January 2025

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Adjusting for principal components can induce collider bias in genome-wide association studies.
Kelsey E Grinde, Brian L Browning, Alexander P Reiner, Timothy A Thornton, Sharon R Browning

PLoS Genet· December 2024

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Yield of genetic association signals from genomes, exomes and imputation in the UK Biobank.
Sheila M Gaynor, Tyler Joseph, Xiaodong Bai, Yuxin Zou, Boris Boutkov, Timothy A Thornton

Nat Genet· November 2024

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Joint testing of rare variant burden scores using non-negative least squares.
Andrey Ziyatdinov, Joelle Mbatchou, Anthony Marcketta, Joshua Backman, Sheila Gaynor, Timothy Thornton

Am J Hum Genet· October 2024

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Admixture Mapping of Chronic Kidney Disease and Risk Factors in Hispanic/Latino Individuals From Central America Country of Origin.
Andrea R V R Horimoto, Quan Sun, James P Lash, Martha L Daviglus, Jianwen Cai, Timothy A Thornton

Circ Genom Precis Med· August 2024

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A deep catalogue of protein-coding variation in 983,578 individuals.
Kathie Y Sun, Xiaodong Bai, Siying Chen, Suying Bao, Chuanyi Zhang, Timothy Thornton

Nature· July 2024

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Adjusting for principal components can induce spurious associations in genome-wide association studies in admixed populations.
Kelsey E Grinde, Brian L Browning, Alexander P Reiner, Timothy A Thornton, Sharon R Browning

bioRxiv· April 2024

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Improving polygenic risk prediction in admixed populations by explicitly modeling ancestral-differential effects via GAUDI.
Quan Sun, Bryce T Rowland, Jiawen Chen, Anna V Mikhaylova, Christy Avery, Timothy A Thornton

Nat Commun· February 2024

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Author Correction: Genotyping, sequencing and analysis of 140,000 adults from Mexico City.
Andrey Ziyatdinov, Jason Torres, Jesús Alegre-Díaz, Joshua Backman, Joelle Mbatchou, Timothy A Thornton

Nature· February 2024

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A deep catalog of protein-coding variation in 985,830 individuals.
Kathie Y Sun, Xiaodong Bai, Siying Chen, Suying Bao, Manav Kapoor, Timothy Thornton

bioRxiv· November 2023

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Genotyping, sequencing and analysis of 140,000 adults from Mexico City.
Andrey Ziyatdinov, Jason Torres, Jesús Alegre-Díaz, Joshua Backman, Joelle Mbatchou, Timothy A Thornton

Nature· October 2023

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X-Chromosome Association Study in Latin American Cohorts Identifies New Loci in Parkinson's Disease.
Thiago P Leal, Shilpa C Rao, Jennifer N French-Kwawu, Mateus H Gouveia, Victor Borda, Timothy A Thornton

Mov Disord· September 2023

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Associations of cardiometabolic polygenic risk scores with cardiovascular disease in African Americans.
Workalemahu Tsegaselassie, Ying Jian, Gebremeskel G Berhanu, Lu Tianyuan, Mohanty April, Thornton A Timothy

Res Sq· August 2023

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Admixture mapping implicates 13q33.3 as ancestry-of-origin locus for Alzheimer disease in Hispanic and Latino populations.
Andrea R V R Horimoto, Lisa A Boyken, Elizabeth E Blue, Kelsey E Grinde, Rafael A Nafikov, Timothy A Thornton

HGG Adv· July 2023

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X-Chromosome Association Study in Latin American Cohorts Identifies New Loci in Parkinson Disease.
Thiago P Leal, Jennifer N French-Kwawu, Mateus H Gouveia, Victor Borda, Miguel Inca-Martinez, Timothy A Thornton

medRxiv· February 2023

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Association of African Ancestry-Specific APOE Missense Variant R145C With Risk of Alzheimer Disease.
Yann Le Guen, Ana-Caroline Raulin, Mark W Logue, Richard Sherva, Michael E Belloy, Timothy A Thornton

JAMA· February 2023

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Polygenic risk prediction and SNCA haplotype analysis in a Latino Parkinson's disease cohort.
Douglas P Loesch, Andrea R V R Horimoto, Elif Irem Sarihan, Miguel Inca-Martinez, Emily Mason, Timothy A Thornton

Parkinsonism Relat Disord· September 2022

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Associating sleep problems with advanced cancer diagnosis, and immune checkpoint treatment outcomes: a pilot study.
Arthur Sillah, Ulrike Peters, Nathaniel F Watson, Scott S Tykodi, Evan T Hall, Timothy Thornton

Support Care Cancer· May 2022

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Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program.
Xiaowei Hu, Dandi Qiao, Wonji Kim, Matthew Moll, Pallavi P Balte, Timothy A Thornton

Am J Hum Genet· May 2022

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Protein prediction for trait mapping in diverse populations.
Ryan Schubert, Elyse Geoffroy, Isabelle Gregga, Ashley J Mulford, Francois Aguet, Timothy A Thornton

PLoS One· March 2022

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Sleep problems and risk of cancer incidence and mortality in an older cohort: The Cardiovascular Health Study (CHS).
Arthur Sillah, Nathaniel F Watson, Ulrike Peters, Mary L Biggs, F Javier Nieto, Timothy Thornton

Cancer Epidemiol· February 2022

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Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed.
Margaret A Taub, Matthew P Conomos, Rebecca Keener, Kruthika R Iyer, Joshua S Weinstock, Timothy Thornton

Cell Genom· January 2022

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Soluble Urokinase Plasminogen Activator Receptor: Genetic Variation and Cardiovascular Disease Risk in Black Adults.
Nels C Olson, Laura M Raffield, Anne H Moxley, Tyne W Miller-Fleming, Paul L Auer, Timothy A Thornton

Circ Genom Precis Med· December 2021

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