Publications by authors named "Timothy Vyse"

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Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland.
Mandi M Wiley, Marcin Radziszewski, Bhuwan Khatri, Michelle L Joachims, Kandice L Tessneer, Timothy J Vyse

Ann Rheum Dis· September 2025

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Haematopoietic stem cell-derived immune cells have reduced X chromosome inactivation skewing in systemic lupus erythematosus.
Amy L Roberts, Alessandro Morea, Ariella Amar, Magdalena West, Sarah Karrar, Timothy J Vyse

Ann Rheum Dis· September 2024

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Cross-talk between ILC2 and Gata3 T locally constrains adaptive type 2 immunity.
Julie Stockis, Thomas Yip, Julia Moreno-Vicente, Oliver Burton, Youhani Samarakoon, Timothy Vyse

Sci Immunol· July 2024

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Genetic mapping across autoimmune diseases reveals shared associations and mechanisms.
Matthew R Lincoln, Noah Connally, Pierre-Paul Axisa, Christiane Gasperi, Mitja Mitrovic, Timothy J Vyse

Nat Genet· May 2024

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A review of genetic risk in systemic lupus erythematosus.
Suri Guga, Yuxuan Wang, Deborah Cunninghame Graham, Timothy J Vyse

Expert Rev Clin Immunol· November 2023

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Variants in the autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland.
Mandi M Wiley, Bhuwan Khatri, Michelle L Joachims, Kandice L Tessneer, Anna M Stolarczyk, Timothy J Vyse

bioRxiv· October 2023

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Genetics of SLE: does this explain susceptibility and severity across racial groups?
Karin Demkova, David L Morris, Timothy J Vyse

Rheumatology (Oxford)· March 2023

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Comprehensive genetic and functional analyses of Fc gamma receptors influence on response to rituximab therapy for autoimmunity.
James I Robinson, Md Yuzaiful Md Yusof, Vinny Davies, Dawn Wild, Michael Morgan, Timothy J Vyse

EBioMedicine· December 2022

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COVID-19 and systemic lupus erythematosus genetics: A balance between autoimmune disease risk and protection against infection.
Yuxuan Wang, Suri Guga, Kejia Wu, Zoe Khaw, Konstantinos Tzoumkas, Timothy J Vyse

PLoS Genet· November 2022

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Age acquired skewed X chromosome inactivation is associated with adverse health outcomes in humans.
Amy L Roberts, Alessandro Morea, Ariella Amar, Antonino Zito, Julia S El-Sayed Moustafa, Timothy J Vyse

Elife· November 2022

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Complement C4, the Major Histocompatibility Complex, and Autoimmunity.
Timothy J Vyse, Betty P Tsao

Arthritis Rheumatol· August 2022

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Immunodeficiency, autoimmunity, and increased risk of B cell malignancy in humans with mutations.
William Rae, John M Sowerby, Dorit Verhoeven, Mariam Youssef, Prasanti Kotagiri, Timothy J Vyse

Sci Immunol· August 2022

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Nucleolin acts as the receptor for C1QTNF4 and supports C1QTNF4-mediated innate immunity modulation.
Susan K Vester, Rebecca L Beavil, Steven Lynham, Andrew J Beavil, Deborah S Cunninghame Graham, Timothy J Vyse

J Biol Chem· August 2021

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Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups.
Yong-Fei Wang, Yan Zhang, Zhiming Lin, Huoru Zhang, Ting-You Wang, Timothy J Vyse

Nat Commun· February 2021

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Identification of susceptibility loci for Takayasu arteritis through a large multi-ancestral genome-wide association study.
Lourdes Ortiz-Fernández, Güher Saruhan-Direskeneli, Fatma Alibaz-Oner, Sema Kaymaz-Tahra, Patrick Coit, Timothy J Vyse

Am J Hum Genet· January 2021

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Trans-Ancestral Fine-Mapping and Epigenetic Annotation as Tools to Delineate Functionally Relevant Risk Alleles at and in Systemic Lupus Erythematosus.
Timothy J Vyse, Deborah S Cunninghame Graham

Int J Mol Sci· November 2020

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Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues.
Dominika W Gajdasik, Fabrina Gaspal, Emily E Halford, Remi Fiancette, Emma E Dutton, Timothy Vyse

Nat Commun· July 2020

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Independent Replication on Genome-Wide Association Study Signals Identifies as a Novel Locus for Systemic Lupus Erythematosus.
Feixia Zhang, Yong-Fei Wang, Yan Zhang, Zhiming Lin, Yujie Cao, Timothy J Vyse

Front Genet· July 2020

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Genome-wide assessment of genetic risk for systemic lupus erythematosus and disease severity.
Lingyan Chen, Yong-Fei Wang, Lu Liu, Adrianna Bielowka, Rahell Ahmed, Timothy J Vyse

Hum Mol Genet· June 2020

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Complement genes contribute sex-biased vulnerability in diverse disorders.
Nolan Kamitaki, Aswin Sekar, Robert E Handsaker, Heather de Rivera, Katherine Tooley, Timothy J Vyse

Nature· June 2020

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High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus.
Sarah Reid, Andrei Alexsson, Martina Frodlund, David Morris, Johanna K Sandling, Timothy James Vyse

Ann Rheum Dis· March 2020

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Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes.
Lennox Din, Mohammad Sheikh, Nikitha Kosaraju, Karin Ekstrom Smedby, Sasha Bernatsky, Timothy J Vyse

Genet Epidemiol· October 2019

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GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways.
Elena López-Isac, Marialbert Acosta-Herrera, Martin Kerick, Shervin Assassi, Ansuman T Satpathy, Timothy Vyse

Nat Commun· October 2019

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Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus.
Christopher A Odhams, Amy L Roberts, Susan K Vester, Carolina S T Duarte, Charlie T Beales, Timothy J Vyse

Nat Commun· May 2019

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Genome-wide meta-analysis reveals shared new in systemic seropositive rheumatic diseases.
Marialbert Acosta-Herrera, Martin Kerick, David González-Serna, , , Timothy James Vyse

Ann Rheum Dis· March 2019

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