Publications by authors named "Tira Tan"

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Evaluating the impact of relative dose intensity on efficacy of trastuzumab deruxtecan for metastatic breast cancer in the real-world clinical setting.
Han Yi Lee, Vivianne Shih, Jack Junjie Chan, Shun Zi Liong, Ryan Shea Ying Cong Tan, Joshua Zhi Chien Tan, Su-Ming Tan, Tira J Tan

Ann Acad Med Singap· August 2025

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A deep-learning model for quantifying circulating tumour DNA from the density distribution of DNA-fragment lengths.
Guanhua Zhu, Chowdhury Rafeed Rahman, Victor Getty, Denis Odinokov, Probhonjon Baruah, Tira J Tan, Patrick Tan, Daniel Tan, Iain Beehuat Tan

Nat Biomed Eng· March 2025

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Trastuzumab Duocarmazine in Pretreated Human Epidermal Growth Factor Receptor 2-Positive Advanced or Metastatic Breast Cancer: An Open-Label, Randomized, Phase III Trial (TULIP).
Nicholas Turner, Cristina Saura, Philippe Aftimos, Evelyn van den Tweel, Mayke Oesterholt, Tira J Tan

J Clin Oncol· February 2025

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HEalth-Related Quality of Life-Intervention in Survivors of Breast and Other Cancers Experiencing Cancer-Related Fatigue and Associated Cognitive Symptoms Using TraditionAL Chinese Medicine: The 'HERBAL' Trial.
Alexandre Chan, Daniella Chan, Ding Quan Ng, Huang Fang Zheng, Quan Ming Tan, Chia Jie Tan, Tira J Tan

Integr Cancer Ther· January 2025

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Precision Oncology: A Global Perspective on Implementation and Policy Development.
Denis Horgan, Marcel Tanner, Charu Aggarwal, David Thomas, Surbhi Grover, Tira Jing Ying Tan

JCO Glob Oncol· January 2025

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Curative Approaches for Metaplastic Breast Cancer: A Retrospective Cohort Outcome Review.
Ling Fung Nelson Yit, Zhan Hong Sheriff Quek, Tira J Tan, Boon Fei Tan, Puay Hoon Tan, Kiat Tee Benita Tan

Int J Radiat Oncol Biol Phys· December 2024

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The Renewing Intimacy and SExuality Intervention for Female Cancer Survivors: A Feasibility Study.
Irene Teo, Yee Pin Tan, Alyssa Goh, Fang Ting Pan, Tira J Tan

Psychooncology· December 2024

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Using Machine Learning Models to Predict Pathologic Complete Response to Neoadjuvant Chemotherapy in Breast Cancer.
Rayhan Erlangga Rahadian, Hong Qi Tan, Bryan Shihan Ho, Arjunan Kumaran, Andre Villanueva, Ryan Shea Ying Cong Tan, Tira Jing Ying Tan, Veronique Kiak Mien Tan, Benita Kiat Tee Tan

JCO Clin Cancer Inform· November 2024

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Phase II DORA Study of Olaparib with or without Durvalumab as a Chemotherapy-Free Maintenance Strategy in Platinum-Pretreated Advanced Triple-Negative Breast Cancer.
Tira J Tan, Sarah Sammons, Young-Hyuck Im, Lilin She, Kelly Mundy

Clin Cancer Res· April 2024

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The cardioprotective potential of sodium-glucose cotransporter 2-inhibitors in breast cancer therapy-related cardiac dysfunction - A systematic review.
Jun Hua Chong, Wei-Ting Chang, Jack Junjie Chan, Tira Jing Ying Tan, Johan Wai Kay Chan

Curr Probl Cardiol· March 2024

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ENABLE-SG (Educate, Nurture, Advise, Before Life Ends for Singapore) as a proactive palliative care model: protocol for a hybrid type 1 effectiveness-implementation randomized wait-list controlled trial.
Yu Ke, Yin Bun Cheung, Marie Bakitas, J Nicholas Odom, Elaine Lum, Daniel Shao Weng Tan, Tira J Tan

BMC Palliat Care· January 2024

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Expanding the use of PARP inhibitors in breast cancer.
Tira Tan

Clin Adv Hematol Oncol· September 2023

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External validation of the first prognostic nomogram for older adults with cancer.
Yu Ling Tay, Whee Sze Ong, Sherilyn Zi Hui Liew, Anupama Roy Chowdhury, Johan Chan, Tanujaa Rajasekaran, Tira J Tan

Ther Adv Med Oncol· September 2023

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Early Triple-Negative Breast Cancers in a Singapore Cohort Exhibit High PIK3CA Mutation Rates Associated With Low PD-L1 Expression.
Joe Yeong, Denise Goh, Tira J Tan, Benedict Tan, Huren Sivaraj, Puay Hoon Tan

Mod Pathol· April 2023

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Clinical best practices in optimal monitoring, early diagnosis, and effective management of antibody-drug conjugate-induced interstitial lung disease or pneumonitis: a multidisciplinary team approach in Singapore.
Wei Peng Yong, Felicia Sw Teo, Lynette Ls Teo, Matthew Ch Ng, Tira J Tan

Expert Opin Drug Metab Toxicol· December 2022

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Exquisitely Platinum-Sensitive Triple-Negative Breast Cancer, Time for Methylation Testing?
Tira J Tan, J Lynn Fink, Timothy K Tay, Binny Jaradi, Nathan Stone, Puay Hoon Tan, Daniel S Tan

JCO Precis Oncol· November 2022

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A phase I study of an adenoviral vector delivering a MUC1/CD40-ligand fusion protein in patients with advanced adenocarcinoma.
Tira J Tan, W X Gladys Ang, Who-Whong Wang, Hui-Shan Chong, Sze Huey Tan, Aaron C Tan

Nat Commun· October 2022

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Multi-center evaluation of artificial intelligent imaging and clinical models for predicting neoadjuvant chemotherapy response in breast cancer.
Tan Hong Qi, Ong Hiok Hian, Arjunan Muthu Kumaran, Tira J Tan, Tan Ryan Ying Cong, Su Ming Tan, Veronique Kiak Mien Tan

Breast Cancer Res Treat· May 2022

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Association between Breast Cancer Polygenic Risk Score and Chemotherapy-Induced Febrile Neutropenia: Null Results.
Seeu Si Ong, Peh Joo Ho, Alexis Jiaying Khng, Elaine Hsuen Lim, Fuh Yong Wong, Benita Kiat-Tee Tan, Ern Yu Tan, Su-Ming Tan, Veronique Kiak Mien Tan, Tira Jing Ying Tan, Siau Wei Tang

Cancers (Basel)· May 2022

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A phase 1 study of the safety, pharmacokinetics and pharmacodynamics of escalating doses followed by dose expansion of the selective inhibitor of nuclear export (SINE) selinexor in Asian patients with advanced or metastatic malignancies.
Jingshan Ho, Valerie Heong, Wei Peng Yong, Ross Soo, Cheng Ean Chee, Tiffany Tang, Tira J Y Tan, Daniel S W Tan, David S P Tan

Ther Adv Med Oncol· April 2022

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Endophthalmitis Treated Successfully With Isavuconazole: A Case Report.
Edwin Chong Yu Sng, Ai Ling Tan, Peijun Yvonne Zhou, Tira J Tan, Samanthila Waduthantri, Ban Hock Tan

Open Forum Infect Dis· December 2021

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Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer.
Ser Yue Loo, Li Ping Toh, William Haowei Xie, Elina Pathak, Wilson Tan, Tira J Tan, Veronique Tan, Benita Tan, Puay Hoon Tan

Sci Adv· October 2021

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First-in-human phase I/Ib open-label dose-escalation study of GWN323 (anti-GITR) as a single agent and in combination with spartalizumab (anti-PD-1) in patients with advanced solid tumors and lymphomas.
Sarina A Piha-Paul, Ravit Geva, Tira J Tan, Darren Wt Lim, Cinta Hierro

J Immunother Cancer· August 2021

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Complementary Sequential Circulating Tumor Cell (CTC) and Cell-Free Tumor DNA (ctDNA) Profiling Reveals Metastatic Heterogeneity and Genomic Changes in Lung Cancer and Breast Cancer.
Say Li Kong, Xingliang Liu, Swee Jin Tan, Joyce A Tai, Ler Yee Phua, Tira J Tan, Daniel Shao-Weng Tan

Front Oncol· July 2021

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Effects of housing value and medical subsidy on treatment and outcomes of breast cancer patients in Singapore: A retrospective cohort study.
Fuh Yong Wong, Ru Xin Wong, Siqin Zhou, Whee Sze Ong, Pin Pin Pek, Benita Kiat Tee Tan, Veronique Kiak Mien Tan, Su-Ming Tan, Tira Jing Ying Tan

Lancet Reg Health West Pac· January 2021

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