Publications by authors named "Tobias Goschzik"

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Histological and molecular characterization of endolymphatic sac tumor reveals key differences from its primary differential diagnosis, choroid plexus papilloma.
Lea L Friker, Rebecca Klein, Ralf Clauberg, Tobias Goschzik, Julian P Layer

Histol Histopathol· December 2025

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Recurrent genetic alterations in epigenetically defined pineoblastoma subtypes.
Tobias Goschzik, Mathias Yuan, Elke Pfaff, Manuel E B Müller, Martin Mynarek

Acta Neuropathol Commun· November 2025

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Pitfalls in the evaluation of CDKN2A copy number status in meningioma.
Valentina Zschernack, Giuseppe Pinto, Lea L Friker, Rebecca Klein, Tobias Goschzik

J Neurooncol· July 2025

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Medulloblastoma in children with Fanconi anemia: Association with FA-D1/FA-N, SHH type and poor survival independent of treatment strategies.
Marthe Sönksen, Denise Obrecht-Sturm, Pablo Hernáiz Driever, Axel Sauerbrey, Norbert Graf, Tobias Goschzik

Neuro Oncol· November 2024

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FH-mutant glioma displaying the epigenetic signature of IDH-mutant astrocytomas.
Valentina Zschernack, Christian Thomas, Christina Schaub, Glen Kristiansen, Andreas Waha, Tobias Goschzik

J Neuropathol Exp Neurol· October 2024

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Risk prediction in early childhood sonic hedgehog medulloblastoma treated with radiation-avoiding chemotherapy: Evidence for more than 2 subgroups.
Svenja Tonn, Andrey Korshunov, Denise Obrecht, Martin Sill, Michael Spohn, Tobias Goschzik

Neuro Oncol· August 2023

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Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification.
Jack Goddard, Jemma Castle, Emily Southworth, Anya Fletcher, Stephen Crosier, Tobias Goschzik

Acta Neuropathol· May 2023

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Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts.
Martin Mynarek, Denise Obrecht, Martin Sill, Dominik Sturm, Katja Kloth-Stachnau, Tobias Goschzik

Acta Neuropathol· January 2023

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Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas.
Tobias Goschzik, Martin Mynarek, Evelyn Doerner, Alina Schenk, Isabel Spier

Acta Neuropathol· December 2022

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Molecular pathological insights reveal a high number of unfavorable risk patients among children treated for medulloblastoma and CNS-PNET in Oslo 2005-2017.
Pitt Niehusmann, Einar Stensvold, Henning Leske, Torsten Pietsch, Tobias Goschzik

Pediatr Blood Cancer· September 2022

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Medulloblastoma and Cowden syndrome: Further evidence of an association.
Steffen Albrecht, Barbara Miedzybrodzki, Laura Palma, Van Hung Nguyen, Roy W R Dudley, Tobias Goschzik

Free Neuropathol· January 2022

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Medulloblastoma in Adults: Cytogenetic Phenotypes Identify Prognostic Subgroups.
Tobias Goschzik, Anja Zur Muehlen, Evelyn Doerner, Andreas Waha, Carsten Friedrich

J Neuropathol Exp Neurol· April 2021

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Prognostic effect of whole chromosomal aberration signatures in standard-risk, non-WNT/non-SHH medulloblastoma: a retrospective, molecular analysis of the HIT-SIOP PNET 4 trial.
Tobias Goschzik, Edward C Schwalbe, Debbie Hicks, Amanda Smith, Anja Zur Muehlen

Lancet Oncol· December 2018

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Mutation of a putative MAP kinase consensus site regulates NCAM endocytosis and NCAM-dependent neurite outgrowth.
Tobias Goschzik, Harold Cremer, Vinayaga S Gnanapragassam, Rüdiger Horstkorte, Kaya Bork

Neurosci Res· July 2017

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Medulloblastoma with extensive nodularity: a tumour exclusively of infancy?
Marco Gessi, Tobias Goschzik, Evelyn Dörner, Kathrin Söldner, Christine Schupp

Neuropathol Appl Neurobiol· April 2017

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Genomic Alterations of Adamantinomatous and Papillary Craniopharyngioma.
Tobias Goschzik, Marco Gessi, Verena Dreschmann, Ursel Gebhardt, Linghua Wang

J Neuropathol Exp Neurol· February 2017

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Treatment of Children and Adolescents With Metastatic Medulloblastoma and Prognostic Relevance of Clinical and Biologic Parameters.
André O von Bueren, Rolf-Dieter Kortmann, Katja von Hoff, Carsten Friedrich, Martin Mynarek, Tobias Goschzik

J Clin Oncol· December 2016

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Dysembryoplastic Neuroepithelial Tumor of the Septum Pellucidum and the Supratentorial Midline: Histopathologic, Neuroradiologic, and Molecular Features of 7 Cases.
Marco Gessi, Elke Hattingen, Evelyn Dörner, Tobias Goschzik, Verena Dreschmann

Am J Surg Pathol· June 2016

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Biomarker-driven stratification of disease-risk in non-metastatic medulloblastoma: Results from the multi-center HIT-SIOP-PNET4 clinical trial.
Steven C Clifford, Birgitta Lannering, Ed C Schwalbe, Debbie Hicks, Kieran O'Toole, Tobias Goschzik

Oncotarget· November 2015

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High-Resolution Genomic Analysis of Cribriform Neuroepithelial Tumors of the Central Nervous System.
Marco Gessi, Anna Sophia Japp, Verena Dreschmann, Anja Zur Mühlen, Tobias Goschzik

J Neuropathol Exp Neurol· October 2015

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Molecular stratification of medulloblastoma: comparison of histological and genetic methods to detect Wnt activated tumours.
Tobias Goschzik, Anja Zur Mühlen, Glen Kristiansen, Christine Haberler, Harald Stefanits

Neuropathol Appl Neurobiol· February 2015

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MET T992I mutation in a case of ependymoblastoma/embryonal tumour with multilayered rosettes.
Marco Gessi, Halil Demir, Tobias Goschzik, Torsten Pietsch

J Clin Pathol· November 2014

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PTEN mutations and activation of the PI3K/Akt/mTOR signaling pathway in papillary tumors of the pineal region.
Tobias Goschzik, Marco Gessi, Dorota Denkhaus, Torsten Pietsch

J Neuropathol Exp Neurol· August 2014

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Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort.
Torsten Pietsch, Rene Schmidt, Marc Remke, Andrey Korshunov, Volker Hovestadt, Tobias Goschzik

Acta Neuropathol· July 2014

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FGFR1 mutations in Rosette-forming glioneuronal tumors of the fourth ventricle.
Marco Gessi, Yasmin Abdel Moneim, Jennifer Hammes, Tobias Goschzik, Martin Scholz

J Neuropathol Exp Neurol· June 2014

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