Publications by authors named "Toby C Kent"

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Evaluating the efficacy of upadacitinib in patients with moderate rheumatoid arthritis: a post-hoc analysis of the SELECT phase 3 trials.
Philip G Conaghan, Karel Pavelka, Song-Chou Hsieh, Terri-Leigh Bonnington, Toby C Kent

Rheumatol Adv Pract· February 2023

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The inhibition of human lung fibroblast proliferation and differentiation by Gs-coupled receptors is not predicted by the magnitude of cAMP response.
Maxine J Roberts, Rebecca E Broome, Toby C Kent, Steven J Charlton, Elizabeth M Rosethorne

Respir Res· April 2018

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Comparing the cardiovascular therapeutic indices of glycopyrronium and tiotropium in an integrated rat pharmacokinetic, pharmacodynamic and safety model.
Alexandre Trifilieff, Brian T Ethell, David A Sykes, Kenny J Watson, Steve Collingwood, Toby C Kent

Toxicol Appl Pharmacol· August 2015

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Functional desensitization of the β 2 adrenoceptor is not dependent on agonist efficacy.
Elizabeth M Rosethorne, Michelle E Bradley, Toby C Kent, Steven J Charlton

Pharmacol Res Perspect· February 2015

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High throughput mutagenesis for identification of residues regulating human prostacyclin (hIP) receptor expression and function.
Anke Bill, Elizabeth M Rosethorne, Toby C Kent, Lindsay Fawcett, Lynn Burchell

PLoS One· January 2015

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The antiallergic mast cell stabilizers lodoxamide and bufrolin as the first high and equipotent agonists of human and rat GPR35.
Amanda E MacKenzie, Gianluigi Caltabiano, Toby C Kent, Laura Jenkins, Jennifer E McCallum

Mol Pharmacol· January 2014

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The use of cold plasma technology to reduce carryover in screening assays.
Mohammed Akhlaq, Elizabeth M Rosethorne, Afrah Sattikar, Toby C Kent

J Lab Autom· August 2013

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The Influence of receptor kinetics on the onset and duration of action and the therapeutic index of NVA237 and tiotropium.
David A Sykes, Mark R Dowling, Juliet Leighton-Davies, Toby C Kent, Lindsay Fawcett

J Pharmacol Exp Ther· November 2012

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Quantitative GPCR and ion channel transcriptomics in primary alveolar macrophages and macrophage surrogates.
Paul J Groot-Kormelink, Lindsay Fawcett, Paul D Wright, Martin Gosling, Toby C Kent

BMC Immunol· October 2012

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Development of a generic dual-reporter gene assay for screening G-protein-coupled receptors.
Toby C Kent, Kevin S J Thompson, Louise H Naylor

J Biomol Screen· August 2005

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The effect of ICER on screening methods involving CRE-mediated reporter gene expression.
Daniel M Kemp, Samantha E George, Toby C Kent, Peter J Bungay, Louise H Naylor

J Biomol Screen· April 2002

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