Publications by authors named "Todd J Sullivan"

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Virtual screening reveals allosteric inhibitors of the Toxoplasma gondii thymidylate synthase-dihydrofolate reductase.
Hitesh Sharma, Mark J Landau, Todd J Sullivan, Vidya P Kumar, Markus K Dahlgren

Bioorg Med Chem Lett· February 2014

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Design, Synthesis, and Antiviral Evaluation of Chimeric Inhibitors of HIV Reverse Transcriptase.
Pinar Iyidogan, Todd J Sullivan, Mahendra D Chordia, Kathleen M Frey, Karen S Anderson

ACS Med Chem Lett· December 2013

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Bifunctional inhibition of human immunodeficiency virus type 1 reverse transcriptase: mechanism and proof-of-concept as a novel therapeutic design strategy.
Christopher M Bailey, Todd J Sullivan, Pinar Iyidogan, Julian Tirado-Rives, Raymond Chung

J Med Chem· May 2013

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[d4U]-spacer-[HI-236] double-drug inhibitors of HIV-1 reverse-transcriptase.
Yassir Younis, Roger Hunter, Clare I Muhanji, Ian Hale, Rajinder Singh, Todd J Sullivan

Bioorg Med Chem· July 2010

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Substituted diphenyl ethers as a broad-spectrum platform for the development of chemotherapeutics for the treatment of tularaemia.
Kathleen England, Christopher am Ende, Hao Lu, Todd J Sullivan, Nicole L Marlenee

J Antimicrob Chemother· November 2009

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Synthesis and in vitro antimycobacterial activity of B-ring modified diaryl ether InhA inhibitors.
Christopher W am Ende, Susan E Knudson, Nina Liu, James Childs, Todd J Sullivan

Bioorg Med Chem Lett· May 2008

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Mechanism and inhibition of saFabI, the enoyl reductase from Staphylococcus aureus.
Hua Xu, Todd J Sullivan, Jun-ichiro Sekiguchi, Teruo Kirikae, Iwao Ojima

Biochemistry· April 2008

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Targeting fatty acid biosynthesis for the development of novel chemotherapeutics against Mycobacterium tuberculosis: evaluation of A-ring-modified diphenyl ethers as high-affinity InhA inhibitors.
Melissa E Boyne, Todd J Sullivan, Christopher W amEnde, Hao Lu, Veronica Gruppo

Antimicrob Agents Chemother· October 2007

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High affinity InhA inhibitors with activity against drug-resistant strains of Mycobacterium tuberculosis.
Todd J Sullivan, James J Truglio, Melissa E Boyne, Polina Novichenok, Xujie Zhang

ACS Chem Biol· February 2006

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Inhibition of the bacterial enoyl reductase FabI by triclosan: a structure-reactivity analysis of FabI inhibition by triclosan analogues.
Sharada Sivaraman, Todd J Sullivan, Francis Johnson, Polina Novichenok, Guanglei Cui

J Med Chem· January 2004

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