Publications by authors named "Tom Obrig"

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Role of Shiga/Vero toxins in pathogenesis.
Fumiko Obata, Tom Obrig

Microbiol Spectr· June 2014

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Protection by a recombinant Mycobacterium bovis Bacillus Calmette-Guerin vaccine expressing Shiga toxin 2 B subunit against Shiga toxin-producing Escherichia coli in mice.
Jun Fujii, Mariko Naito, Takashi Yutsudo, Sohkichi Matsumoto, Daniel P Heatherly, Tom Obrig

Clin Vaccine Immunol· December 2012

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Shiga toxin pathogenesis: kidney complications and renal failure.
Tom G Obrig, Diana Karpman

Curr Top Microbiol Immunol· April 2012

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Escherichia coli Shiga Toxin Mechanisms of Action in Renal Disease.
Tom G Obrig

Toxins (Basel)· December 2010

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Distribution of Gb(3) Immunoreactivity in the Mouse Central Nervous System.
Fumiko Obata, Tom Obrig

Toxins (Basel)· August 2010

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Shiga toxin 2 targets the murine renal collecting duct epithelium.
Mitchell A Psotka, Fumiko Obata, Glynis L Kolling, Lisa K Gross, Moin A Saleem, Tom G Obrig

Infect Immun· March 2009

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Shiga toxin 2 affects the central nervous system through receptor globotriaosylceramide localized to neurons.
Fumiko Obata, Koujiro Tohyama, Adrian D Bonev, Glynis L Kolling, Tiffany R Keepers, Tom G Obrig

J Infect Dis· November 2008

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Post-exposure targeting of specific epitopes on ricin toxin abrogates toxin-induced hypoglycemia, hepatic injury, and lethality in a mouse model.
James K Roche, Matthew K Stone, Lisa K Gross, Matthew Lindner, Regina Seaner, Tom G Obrig

Lab Invest· November 2008

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An A2A adenosine receptor agonist, ATL313, reduces inflammation and improves survival in murine sepsis models.
Christopher C Moore, Edward N Martin, Grace H Lee, Tom Obrig, Joel Linden

BMC Infect Dis· October 2008

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Shiga toxin 2 causes apoptosis in human brain microvascular endothelial cells via C/EBP homologous protein.
Jun Fujii, Katie Wood, Fumiko Matsuda, Benedito A Carneiro-Filho, Keilo H Schlegel, Tom Obrig

Infect Immun· August 2008

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ZAK: a MAP3Kinase that transduces Shiga toxin- and ricin-induced proinflammatory cytokine expression.
Dakshina M Jandhyala, Amrita Ahluwalia, Tom Obrig, Cheleste M Thorpe

Cell Microbiol· July 2008

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Immunohistologic techniques for detecting the glycolipid Gb(3) in the mouse kidney and nervous system.
Glynis L Kolling, Fumiko Obata, Lisa K Gross, Tom G Obrig

Histochem Cell Biol· July 2008

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p38 mitogen-activated protein kinase mediates lipopolysaccharide and tumor necrosis factor alpha induction of shiga toxin 2 sensitivity in human umbilical vein endothelial cells.
Matthew K Stone, Glynis L Kolling, Matthew H Lindner, Tom G Obrig

Infect Immun· March 2008

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Monocyte chemoattractant protein 1, macrophage inflammatory protein 1 alpha, and RANTES recruit macrophages to the kidney in a mouse model of hemolytic-uremic syndrome.
Tiffany R Keepers, Lisa K Gross, Tom G Obrig

Infect Immun· March 2007

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CXCL1/KC and CXCL2/MIP-2 are critical effectors and potential targets for therapy of Escherichia coli O157:H7-associated renal inflammation.
James K Roche, Tiffany R Keepers, Lisa K Gross, Regina M Seaner, Tom G Obrig

Am J Pathol· February 2007

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A murine model of HUS: Shiga toxin with lipopolysaccharide mimics the renal damage and physiologic response of human disease.
Tiffany R Keepers, Mitchell A Psotka, Lisa K Gross, Tom G Obrig

J Am Soc Nephrol· December 2006

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Local anesthetic-induced protection against lipopolysaccharide-induced injury in endothelial cells: the role of mitochondrial adenosine triphosphate-sensitive potassium channels.
Manuela J M de Klaver, Gregory S Weingart, Tom G Obrig, George F Rich

Anesth Analg· April 2006

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Caspase and bid involvement in Clostridium difficile toxin A-induced apoptosis and modulation of toxin A effects by glutamine and alanyl-glutamine in vivo and in vitro.
Benedito A Carneiro, Jun Fujii, Gerly A C Brito, Cirle Alcantara, Reinaldo B Oriá, Tom Obrig

Infect Immun· January 2006

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Shiga toxin 2 and lipopolysaccharide induce human microvascular endothelial cells to release chemokines and factors that stimulate platelet function.
Fadila Guessous, Marek Marcinkiewicz, Renata Polanowska-Grabowska, Sudawadee Kongkhum, Daniel Heatherly, Tom Obrig

Infect Immun· December 2005

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Shiga toxin 2 and lipopolysaccharide cause monocytic THP-1 cells to release factors which activate platelet function.
Fadila Guessous, Marek Marcinkiewicz, Renata Polanowska-Grabowska, Tiffany R Keepers, Tom Obrig

Thromb Haemost· November 2005

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Alanyl-glutamine hastens morphologic recovery from 5-fluorouracil-induced mucositis in mice.
Benedito A Carneiro-Filho, Reinaldo B Oriá, Katie Wood Rea, Gerly A C Brito, Jun Fujii, Tom Obrig

Nutrition· October 2004

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Rapid apoptosis induced by Shiga toxin in HeLa cells.
Jun Fujii, Takashi Matsui, Daniel P Heatherly, Kailo H Schlegel, Peter I Lobo, Tom Obrig

Infect Immun· May 2003

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Response to Shiga toxin 1 and 2 in a baboon model of hemolytic uremic syndrome.
Richard L Siegler, Tom G Obrig, Theodore J Pysher, Vernon L Tesh, Nathaniel D Denkers

Pediatr Nephrol· February 2003

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Mechanism of Clostridium difficile toxin A-induced apoptosis in T84 cells.
Gerly A C Brito, Jun Fujji, Benedito A Carneiro-Filho, Aldo A M Lima, Tom Obrig

J Infect Dis· November 2002

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The mouse model of amebic colitis reveals mouse strain susceptibility to infection and exacerbation of disease by CD4+ T cells.
Eric R Houpt, David J Glembocki, Tom G Obrig, Christopher A Moskaluk, Lauren A Lockhart

J Immunol· October 2002

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