Publications by authors named "Tom Seijkens"

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The immune checkpoint inhibitor avelumab increases aortic inflammation on [18F]FDG PET/CT: A retrospective cohort study.
Anniek Strijdhorst, Reindert F Oostveen, Mark P A Schilder, Arthur J A T Braat, Youssef Chahid, Tom T P Seijkens

PLoS One· December 2025

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Immunological features of clear-cell renal-cell carcinoma and resistance to immune checkpoint inhibitors.
Femke H Burgers, Johannes C K van der Mijn, Tom T P Seijkens, Inge Jedema, Axel Bex

Nat Rev Nephrol· October 2025

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Advances in TIL therapy: Expanding the horizons beyond melanoma.
Pauline Wiertsema, Ya Hwee Tan, John B A G Haanen, Tom T P Seijkens, Inge Jedema

Med· August 2025

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Accelerated atherosclerosis associated with immune checkpoint inhibitors: a systematic review and meta-analysis of pre-clinical studies.
Anniek Strijdhorst, Winnie G Vos, Laura A Bosmans, Kim E Dzobo, Pascal J H Kusters, Tom T P Seijkens

Atherosclerosis· June 2025

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Surgical considerations for tumour-infiltrating lymphocyte therapy in melanoma: results from a randomized phase III trial.
Liselotte Tas, Marie B Weitemeyer, Maartje W Rohaan, Troels H Borch, Alexander C J van Akkooi, Tom T P Seijkens

Br J Surg· May 2025

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Arterial inflammation on [F]FDG PET/CT in melanoma patients treated with and without immune checkpoint inhibitors: CHECK-FLAME I.
Elissa A S Polomski, Ellen W Kapiteijn, Julius C Heemelaar, Anne V van der Kolk, Timo M Kalisvaart, Tom T P Seijkens

Atherosclerosis· November 2024

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Tumour-infiltrating lymphocyte therapy for patients with advanced-stage melanoma.
Sebastian Klobuch, Tom T P Seijkens, Ton N Schumacher, John B A G Haanen

Nat Rev Clin Oncol· March 2024

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T cell specific deletion of Casitas B lineage lymphoma-b reduces atherosclerosis, but increases plaque T cell infiltration and systemic T cell activation.
Winnie G Vos, Bram W van Os, Myrthe den Toom, Linda Beckers, Cindy P A A van Roomen, Tom T P Seijkens

Front Immunol· March 2024

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Peritoneal Metastases From Prostate Carcinoma Treated With 177 Lu-PSMA-I&T.
Larissa W van Golen, Tom T P Seijkens, Jeantine M de Feijter, Wouter Vogel

Clin Nucl Med· May 2023

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The emerging role for CAR T cells in solid tumor oncology.
Sebastian Klobuch, Tom T P Seijkens, John B A G Haanen

Chin Clin Oncol· April 2023

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Immuno-PET Imaging of Atherosclerotic Plaques with [Zr]Zr-Anti-CD40 mAb-Proof of Concept.
Kikkie Poels, Maxime Schreurs, Matthijs Jansen, Danielle J Vugts, Tom T P Seijkens

Biology (Basel)· March 2022

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Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease.
Michael Lacy, Christina Bürger, Annelie Shami, Maiwand Ahmadsei, Holger Winkels, Tom T P Seijkens

Nat Commun· June 2021

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Immune checkpoint inhibitor treatment and atherosclerotic cardiovascular disease: an emerging clinical problem.
Kikkie Poels, Suzanne I M Neppelenbroek, Marie José Kersten, M Louisa Antoni, Esther Lutgens, Tom T P Seijkens

J Immunother Cancer· June 2021

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The CD40-CD40L Dyad as Immunotherapeutic Target in Cardiovascular Disease.
Laura A Bosmans, Lena Bosch, Pascal J H Kusters, Esther Lutgens, Tom T P Seijkens

J Cardiovasc Transl Res· February 2021

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'Nur'turing tumor T cell tolerance and exhaustion: novel function for Nuclear Receptor Nur77 in immunity.
Sanne C Lith, Bram W van Os, Tom T P Seijkens, Carlie J M de Vries

Eur J Immunol· November 2020

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Inhibition of PFKFB3 Hampers the Progression of Atherosclerosis and Promotes Plaque Stability.
Kikkie Poels, Johan G Schnitzler, Farahnaz Waissi, Johannes H M Levels, Erik S G Stroes, Tom T P Seijkens

Front Cell Dev Biol· November 2020

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Immune Checkpoint Inhibitor Therapy Aggravates T Cell-Driven Plaque Inflammation in Atherosclerosis.
Kikkie Poels, Mandy M T van Leent, Celine Boutros, Hubert Tissot, Séverine Roy, Tom T P Seijkens

JACC CardioOncol· November 2020

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Short-term regulation of hematopoiesis by lipoprotein(a) results in the production of pro-inflammatory monocytes.
Johan G Schnitzler, Kikkie Poels, Lotte C A Stiekema, Calvin Yeang, Sotirios Tsimikas, Tom T P Seijkens

Int J Cardiol· September 2020

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Glucocorticoid-induced tumour necrosis factor receptor family-related protein (GITR) drives atherosclerosis in mice and is associated with an unstable plaque phenotype and cerebrovascular events in humans.
Annelie Shami, Dorothee Atzler, Laura A Bosmans, Holger Winkels, Svenja Meiler, Tom Seijkens

Eur Heart J· August 2020

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Antibody-Mediated Inhibition of CTLA4 Aggravates Atherosclerotic Plaque Inflammation and Progression in Hyperlipidemic Mice.
Kikkie Poels, Mandy M T van Leent, Myrthe E Reiche, Pascal J H Kusters, Stephan Huveneers, Tom T P Seijkens

Cells· August 2020

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E3 Ubiquitin Ligases as Immunotherapeutic Target in Atherosclerotic Cardiovascular Disease.
Kikkie Poels, Winnie G Vos, Esther Lutgens, Tom T P Seijkens

Front Cardiovasc Med· June 2020

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Author Correction: Ablation of CD8α dendritic cell mediated cross-presentation does not impact atherosclerosis in hyperlipidemic mice.
Bart Legein, Edith M Janssen, Thomas L Theelen, Marion J Gijbels, Joep Walraven, Tom T P Seijkens

Sci Rep· May 2020

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Interruption of the CXCL13/CXCR5 Chemokine Axis Enhances Plasma IgM Levels and Attenuates Atherosclerosis Development.
Emiel P C van der Vorst, Isabelle Daissormont, Maria Aslani, Tom Seijkens, Erwin Wijnands

Thromb Haemost· February 2020

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The therapeutic potential of targeting CD40-TRAF6 pathway in cardiovascular Diseases.
Lena Bosch, Judith J de Haan, Tom T P Seijkens, Claudia M van Tiel, Maike A D Brans

Int J Cardiol· February 2020

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Cancer patients receiving immune checkpoint inhibitor therapy are at an increased risk for atherosclerotic cardiovascular disease.
Esther Lutgens, Tom T P Seijkens

J Immunother Cancer· February 2020

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