Publications by authors named "Tomas Rousar"

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Novel tacrine-based multi-target directed Ligands: Enhancing cholinesterase inhibition, NMDA receptor antagonism, and CNS bioavailability for Alzheimer's disease treatment.
Barbora Svobodova, Zuzana Moravcova, Anna Misiachna, Gabriela Novakova, Ales Marek, Tomas Rousar

Eur J Med Chem· August 2025

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TiO P25 nanoparticles induce mitochondrial damage and increased glutathione synthesis in SH-SY5Y neural cells.
Stepanka Jelinkova, Jana Bacova, Erika Rousarova, Pavlina Nyvltova, Petr Knotek, Tomas Rousar

Food Chem Toxicol· August 2025

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Glutamate utilization fuels rapid production of mitochondrial ROS in dendritic cells and drives systemic inflammation during tularemia.
Ivo Fabrik, Petra Spidlova, Lukas Prchal, Daniela Fabrikova, Ina Viduka, Tomas Rousar

Sci Adv· August 2025

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Ultrathin ALD Coatings of Zr and V Oxides on Anodic TiO Nanotube Layers: Comparison of the Osteoblast Cell Growth.
Kaushik Baishya, Jana Bacova, Bachar Al Chimali, Jan Capek, Jan Michalicka, Tomas Rousar

ACS Appl Mater Interfaces· January 2025

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Enhancement of biocompatibility of anodic nanotube structures on biomedical Ti-6Al-4V alloy via ultrathin TiO coatings.
Marcela Sepúlveda, Jan Capek, Kaushik Baishya, Jhonatan Rodriguez-Pereira, Jana Bacova, Tomas Rousar

Front Bioeng Biotechnol· December 2024

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Mitochondrial damage precedes the changes of glutathione metabolism in CdCl treated neuronal SH-SY5Y cells.
Pavlina Nyvltova, Jan Capek, Jiri Handl, Filip Petira, Erika Rousarova, Tomas Rousar

Food Chem Toxicol· November 2024

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2D TiO Nanosheets Decorated Via Sphere-Like BiVO: A Promising Non-Toxic Material for Liquid Phase Photocatalysis and Bacterial Eradication.
Muhammad Bilal Hanif, Jana Bacova, Viktoriia Berezenko, Yilan Zeng, Emil Paluch, Tomas Rousar

ChemSusChem· September 2024

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Ultrathin TiO Coatings via Atomic Layer Deposition Strongly Improve Cellular Interactions on Planar and Nanotubular Biomedical Ti Substrates.
Jan Capek, Marcela Sepúlveda, Jana Bacova, Jhonatan Rodriguez-Pereira, Raul Zazpe, Tomas Rousar

ACS Appl Mater Interfaces· February 2024

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Cysteine conjugates of acetaminophen and p-aminophenol are potent inducers of cellular impairment in human proximal tubular kidney HK-2 cells.
Tomas Rousar, Jiri Handl, Jan Capek, Pavlina Nyvltova, Erika Rousarova

Arch Toxicol· November 2023

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Development of submicromolar 17β-HSD10 inhibitors and their in vitro and in vivo evaluation.
Ondrej Benek, Michaela Vaskova, Marketa Miskerikova, Monika Schmidt, Rudolf Andrys, Tomas Rousar

Eur J Med Chem· October 2023

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Structure-Guided Design of -Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease.
Barbora Svobodova, Lenka Pulkrabkova, Dawid Panek, Anna Misiachna, Marharyta Kolcheva, Tomas Rousar

Int J Mol Sci· May 2023

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Removal of manganese by adsorption onto newly synthesized TiO-based adsorbent during drinking water treatment.
Katerina Fialova, Monika Motlochova, Lenka Cermakova, Katerina Novotna, Jana Bacova, Tomas Rousar

Environ Technol· April 2023

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The comparison of biological effects of bacterial and synthetic melanins in neuroblastoma cells.
Jiri Handl, Pavlina Nyvltova, Jan Capek, Petr Cesla, Anichka Hovsepyan, Tomas Rousar

Food Chem Toxicol· October 2022

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Evaluating the Use of TiO Nanoparticles for Toxicity Testing in Pulmonary A549 Cells.
Jana Bacova, Petr Knotek, Katerina Kopecka, Ludek Hromadko, Jan Capek, Tomas Rousar

Int J Nanomedicine· September 2022

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Optimization of gradient reversed phase high performance liquid chromatography analysis of acetaminophen oxidation metabolites using linear and non-linear retention model.
Jana Vanova, David Malinak, Rudolf Andrys, Miroslav Kubat, Tomas Mikysek, Erika Rousarova, Tomas Rousar

J Chromatogr A· April 2022

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Author Correction: Quantitative spectrofluorometric assay detecting nuclear condensation and fragmentation in intact cells.
Pavlina Majtnerova, Jan Capek, Filip Petira, Jiri Handl, Tomas Rousar

Sci Rep· September 2021

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Detection of Oxidative Stress Induced by Nanomaterials in Cells-The Roles of Reactive Oxygen Species and Glutathione.
Jan Čapek, Tomáš Roušar

Molecules· August 2021

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Quantitative spectrofluorometric assay detecting nuclear condensation and fragmentation in intact cells.
Pavlina Majtnerova, Jan Capek, Filip Petira, Jiri Handl, Tomas Rousar

Sci Rep· June 2021

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Effects of Charged Oxime Reactivators on the HK-2 Cell Line in Renal Toxicity Screening.
Jiri Handl, David Malinak, Jan Capek, Rudolf Andrys, Erika Rousarova, Tomas Rousar

Chem Res Toxicol· March 2021

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2-Propargylamino-naphthoquinone derivatives as multipotent agents for the treatment of Alzheimer's disease.
Eva Mezeiova, Jana Janockova, Rudolf Andrys, Ondrej Soukup, Tereza Kobrlova, Tomas Rousar

Eur J Med Chem· February 2021

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Thin TiO Coatings by ALD Enhance the Cell Growth on TiO Nanotubular and Flat Substrates.
Martin Motola, Jan Capek, Raul Zazpe, Jana Bacova, Ludek Hromadko, Tomas Rousar

ACS Appl Bio Mater· September 2020

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An overview of apoptosis assays detecting DNA fragmentation.
Pavlína Majtnerová, Tomáš Roušar

Mol Biol Rep· October 2018

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Comparison of glutathione levels measured using optimized monochlorobimane assay with those from ortho-phthalaldehyde assay in intact cells.
Jan Čapek, Martina Hauschke, Lenka Brůčková, Tomáš Roušar

J Pharmacol Toxicol Methods· November 2017

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Neutrophil gelatinase-associated lipocalin production negatively correlates with HK-2 cell impairment: Evaluation of NGAL as a marker of toxicity in HK-2 cells.
Martina Hauschke, Erika Roušarová, Pavel Flídr, Jan Čapek, Antonín Libra

Toxicol In Vitro· March 2017

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Difficulties associated with the structural analysis of proteins susceptible to form aggregates: The case of Tau protein as a biomarker of Alzheimer's disease.
Lenka Hromadkova, Rudolf Kupcik, Barbora Jankovicova, Tomas Rousar, Daniela Ripova

J Sep Sci· February 2016

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