Publications by authors named "Tonis Ord"

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AP-1 elements in the promoter and second intron mediate endoplasmic reticulum stress-induced expression of the GPAT3 gene.
Daima Örd, Tiit Örd, Elina Gluboki, Tõnis Örd

Sci Rep· December 2025

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Genome-wide census of ATF4 binding sites and functional profiling of trait-associated genetic variants overlapping ATF4 binding motifs.
Tiit Örd, Daima Örd, Priit Adler, Tõnis Örd

PLoS Genet· October 2023

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Pharmacological or TRIB3-Mediated Suppression of ATF4 Transcriptional Activity Promotes Hepatoma Cell Resistance to Proteasome Inhibitor Bortezomib.
Tiit Örd, Daima Örd, Minna U Kaikkonen, Tõnis Örd

Cancers (Basel)· May 2021

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A human-specific VNTR in the TRIB3 promoter causes gene expression variation between individuals.
Tiit Örd, Tarmo Puurand, Daima Örd, Tarmo Annilo, Märt Möls

PLoS Genet· August 2020

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TRIB3 limits FGF21 induction during in vitro and in vivo nutrient deficiencies by inhibiting C/EBP-ATF response elements in the Fgf21 promoter.
Tiit Örd, Daima Örd, Tõnis Örd

Biochim Biophys Acta Gene Regul Mech· March 2018

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Mammalian Pseudokinase TRIB3 in Normal Physiology and Disease: Charting the Progress in Old and New Avenues.
Tiit Ord, Tonis Ord

Curr Protein Pept Sci· November 2017

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The transcription factor CHOP, an effector of the integrated stress response, is required for host sensitivity to the fungal intracellular pathogen Histoplasma capsulatum.
Bevin C English, Nancy Van Prooyen, Tiit Örd, Tõnis Örd, Anita Sil

PLoS Pathog· September 2017

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Evidence for a role of TRIB3 in the regulation of megakaryocytopoiesis.
Lee Butcher, Maninder Ahluwalia, Tiit Örd, Jessica Johnston, Roger H Morris

Sci Rep· July 2017

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The C/ebp-Atf response element (CARE) location reveals two distinct Atf4-dependent, elongation-mediated mechanisms for transcriptional induction of aminoacyl-tRNA synthetase genes in response to amino acid limitation.
Jixiu Shan, Fan Zhang, Jason Sharkey, Tiffany A Tang, Tönis Örd

Nucleic Acids Res· November 2016

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TRIB3 increases cell resistance to arsenite toxicity by limiting the expression of the glutathione-degrading enzyme CHAC1.
Daima Örd, Tiit Örd, Tuuliki Biene, Tõnis Örd

Biochim Biophys Acta· November 2016

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TRIB3 enhances cell viability during glucose deprivation in HEK293-derived cells by upregulating IGFBP2, a novel nutrient deficiency survival factor.
Tiit Örd, Daima Örd, Priit Adler, Jaak Vilo, Tõnis Örd

Biochim Biophys Acta· October 2015

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Trib3 is developmentally and nutritionally regulated in the brain but is dispensable for spatial memory, fear conditioning and sensing of amino acid-imbalanced diet.
Tiit Örd, Jürgen Innos, Kersti Lilleväli, Triin Tekko, Silva Sütt

PLoS One· January 2015

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Trib3 is regulated by IL-3 and affects bone marrow-derived mast cell survival and function.
Tiit Ord, Daima Ord, Sulev Kuuse, Mario Plaas, Tõnis Ord

Cell Immunol· November 2012

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Amino acid availability controls TRB3 transcription in liver through the GCN2/eIF2α/ATF4 pathway.
Valérie Carraro, Anne-Catherine Maurin, Sarah Lambert-Langlais, Julien Averous, Cédric Chaveroux, Daima Ord, Tõnis Ord

PLoS One· December 2010

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Human TRB3 is upregulated in stressed cells by the induction of translationally efficient mRNA containing a truncated 5'-UTR.
Tiit Ord, Daima Ord, Mardo Kõivomägi, Kadri Juhkam, Tõnis Ord

Gene· September 2009

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Elevated ATF4 expression, in the absence of other signals, is sufficient for transcriptional induction via CCAAT enhancer-binding protein-activating transcription factor response elements.
Jixiu Shan, Daima Ord, Tõnis Ord, Michael S Kilberg

J Biol Chem· August 2009

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TRB3 protects cells against the growth inhibitory and cytotoxic effect of ATF4.
Daima Ord, Kati Meerits, Tõnis Ord

Exp Cell Res· October 2007

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Characterization of human NIPK (TRB3, SKIP3) gene activation in stressful conditions.
Daima Ord, Tõnis Ord

Biochem Biophys Res Commun· April 2005

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Mouse NIPK interacts with ATF4 and affects its transcriptional activity.
Daima Ord, Tõnis Ord

Exp Cell Res· June 2003

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