Publications by authors named "Trevor A Graham"

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Epigenetically driven and early immune evasion in colorectal cancer evolution.
Eszter Lakatos, Vinaya Gunasri, Luis Zapata, Jacob Househam, Timon Heide, Trevor A Graham

Nat Genet· December 2025

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Research priorities for cancers of the oesophagus and stomach: recommendations from a UK and Ireland patient and healthcare professional partnership exercise.
Christopher M Jones, Wee Han Ng, Laura Tincknell, Dylan P McClurg, Emily Adam, Trevor A Graham

Gut· November 2025

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Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control.
Helen Hockings, Eszter Lakatos, Weini Huang, Maximilian Mossner, Mohammed A Khan, Trevor A Graham

Cancer Res· September 2025

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Fluctuating DNA methylation tracks cancer evolution at clinical scale.
Calum Gabbutt, Martí Duran-Ferrer, Heather E Grant, Diego Mallo, Ferran Nadeu, Trevor A Graham

Nature· September 2025

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Epigenetic Heritability of Cell Plasticity Drives Cancer Drug Resistance through a One-to-Many Genotype-to-Phenotype Paradigm.
Erica A Oliveira, Salvatore Milite, Javier Fernandez-Mateos, George D Cresswell, Erika Yara-Romero, Trevor A Graham

Cancer Res· August 2025

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Mathematical modelling of cancer cell evolution and plasticity.
Chloé Colson, Frederick Jh Whiting, Ann-Marie Baker, Trevor A Graham

Curr Opin Cell Biol· August 2025

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Using FFPEsig to Remove Formalin-Induced Artifacts and Characterize Mutational Signatures in Cancer.
Qingli Guo, Ann-Marie Baker, Ville Mustonen, Trevor A Graham

Methods Mol Biol· August 2025

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Quantitative measurement of phenotype dynamics during cancer drug resistance evolution using genetic barcoding.
Frederick J H Whiting, Maximilian Mossner, Calum Gabbutt, Christopher Kimberley, Chris P Barnes, Trevor A Graham

Nat Commun· June 2025

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Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of esophageal adenocarcinoma.
Melissa Barroux, Jacob Househam, Eszter Lakatos, Tahel Ronel, Ann-Marie Baker, Trevor A Graham

Nat Cancer· May 2025

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Stratified Medicine Pediatrics: Cell-Free DNA and Serial Tumor Sequencing Identifies Subtype-Specific Cancer Evolution and Epigenetic States.
Sally L George, Claire Lynn, Reda Stankunaite, Debbie Hughes, Carolin M Sauer, Trevor A Graham

Cancer Discov· April 2025

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Low-coverage whole genome sequencing of low-grade dysplasia strongly predicts advanced neoplasia risk in ulcerative colitis.
Ibrahim Al Bakir, Kit Curtius, George D Cresswell, Heather E Grant, Nadia Nasreddin, Trevor A Graham

Gut· April 2025

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Deep Learning for Biomarker Discovery in Cancer Genomes.
Michaela Unger, Chiara M L Loeffler, Laura Žigutytė, Srividhya Sainath, Tim Lenz, Trevor A Graham

bioRxiv· January 2025

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Plasticity in metastatic colorectal cancer.
Frederick J H Whiting, Trevor A Graham

Dev Cell· January 2025

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The tumour histopathology "glossary" for AI developers.
Soham Mandal, Ann-Marie Baker, Trevor A Graham, Konstantin Bräutigam

PLoS Comput Biol· January 2025

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The genomic landscape of 2,023 colorectal cancers.
Alex J Cornish, Andreas J Gruber, Ben Kinnersley, Daniel Chubb, Anna Frangou, Trevor A Graham

Nature· September 2024

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Dynamic Prediction of Advanced Colorectal Neoplasia in Inflammatory Bowel Disease.
Anouk M Wijnands, Bas B L Penning de Vries, Maurice W M D Lutgens, Zeinab Bakhshi, Ibrahim Al Bakir, Trevor A Graham

Clin Gastroenterol Hepatol· August 2024

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Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer.
Hamzeh Kayhanian, William Cross, Suzanne E M van der Horst, Panagiotis Barmpoutis, Eszter Lakatos, Trevor A Graham

Nat Genet· July 2024

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Low coverage whole genome sequencing of low-grade dysplasia strongly predicts colorectal cancer risk in ulcerative colitis.
Ibrahim Al Bakir, Kit Curtius, George D Cresswell, Heather E Grant, Nadia Nasreddin, Trevor A Graham

medRxiv· July 2024

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Profiling of Copy Number Alterations Using Low-Coverage Whole-Genome Sequencing Informs Differential Diagnosis and Prognosis in Primary Cutaneous Follicle Center Lymphoma.
Bence Bátai, Laura Kiss, Luca Varga, Ákos Nagy, Jacob Househam, Trevor A Graham

Mod Pathol· May 2024

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FUME-TCRseq Enables Sensitive and Accurate Sequencing of the T-cell Receptor from Limited Input of Degraded RNA.
Ann-Marie Baker, Gayathri Nageswaran, Pablo Nenclares, Tahel Ronel, Kane Smith, Trevor A Graham

Cancer Res· May 2024

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Defining an Optimized Workflow for Enriching and Analyzing Residual Tumor Populations Using Intracellular Markers.
Eve M Coulter, Findlay Bewicke-Copley, Maximilian Mossner, Trevor A Graham, Jude Fitzgibbon

J Mol Diagn· April 2024

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Poor Diagnostic Reproducibility in the Identification of Nonconventional Dysplasia in Colitis Impacts the Application of Histologic Stratification Tools.
Nadia Nasreddin, Marnix Jansen, Maurice B Loughrey, Lai Mun Wang, Viktor H Koelzer, Trevor A Graham

Mod Pathol· March 2024

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Epigenome and early selection determine the tumour-immune evolutionary trajectory of colorectal cancer.
Eszter Lakatos, Vinaya Gunasri, Luis Zapata, Jacob Househam, Timon Heide, Trevor A Graham

bioRxiv· February 2024

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Contribution of pks E. coli mutations to colorectal carcinogenesis.
Bingjie Chen, Daniele Ramazzotti, Timon Heide, Inmaculada Spiteri, Javier Fernandez-Mateos, Trevor A Graham

Nat Commun· November 2023

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