Publications by authors named "Troy Brady"

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Allosteric inhibition of human immunodeficiency virus integrase: late block during viral replication and abnormal multimerization involving specific protein domains.
Kushol Gupta, Troy Brady, Benjamin M Dyer, Nirav Malani, Young Hwang

J Biol Chem· July 2014

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piggyBac transposase tools for genome engineering.
Xianghong Li, Erin R Burnight, Ashley L Cooney, Nirav Malani, Troy Brady

Proc Natl Acad Sci U S A· June 2013

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Recombinant adeno-associated virus integration sites in murine liver after ornithine transcarbamylase gene correction.
Li Zhong, Nirav Malani, Mengxin Li, Troy Brady, Jun Xie

Hum Gene Ther· May 2013

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Quantitation of HIV DNA integration: effects of differential integration site distributions on Alu-PCR assays.
Troy Brady, Brendan J Kelly, Frances Male, Shoshannah Roth, Aubrey Bailey

J Virol Methods· April 2013

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Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV.
Pablo Tebas, David Stein, Gwendolyn Binder-Scholl, Rithun Mukherjee, Troy Brady

Blood· February 2013

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Directly infected resting CD4+T cells can produce HIV Gag without spreading infection in a model of HIV latency.
Matthew J Pace, Erin H Graf, Luis M Agosto, Angela M Mexas, Frances Male, Troy Brady

PLoS Pathog· January 2013

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Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells.
John Scholler, Troy L Brady, Gwendolyn Binder-Scholl, Wei-Ting Hwang, Gabriela Plesa

Sci Transl Med· May 2012

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HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency.
Torsten Schaller, Karen E Ocwieja, Jane Rasaiyaah, Amanda J Price, Troy L Brady

PLoS Pathog· December 2011

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Distribution of lentiviral vector integration sites in mice following therapeutic gene transfer to treat β-thalassemia.
Keshet Ronen, Olivier Negre, Shannah Roth, Charlotte Colomb, Nirav Malani, Troy Brady

Mol Ther· July 2011

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A method to sequence and quantify DNA integration for monitoring outcome in gene therapy.
Troy Brady, Shoshannah L Roth, Nirav Malani, Gary P Wang, Charles C Berry

Nucleic Acids Res· June 2011

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Nondividing cells: a safer bet for integrating vectors?
Troy Brady, Frederic D Bushman

Mol Ther· April 2011

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HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2.
Karen E Ocwieja, Troy L Brady, Keshet Ronen, Alyssa Huegel, Shoshannah L Roth

PLoS Pathog· March 2011

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Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia.
Marina Cavazzana-Calvo, Emmanuel Payen, Olivier Negre, Gary Wang, Kathleen Hehir, Troy Brady

Nature· September 2010

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HIV integration site distributions in resting and activated CD4+ T cells infected in culture.
Troy Brady, Luis M Agosto, Nirav Malani, Charles C Berry, Una O'Doherty

AIDS· July 2009

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Methods for integration site distribution analyses in animal cell genomes.
Angela Ciuffi, Keshet Ronen, Troy Brady, Nirav Malani, Gary Wang

Methods· April 2009

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Integration target site selection by a resurrected human endogenous retrovirus.
Troy Brady, Young Nam Lee, Keshet Ronen, Nirav Malani, Charles C Berry

Genes Dev· March 2009

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Targeting integration of the Saccharomyces Ty5 retrotransposon.
Troy L Brady, Clarice L Schmidt, Daniel F Voytas

Methods Mol Biol· April 2008

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Retrotransposon target site selection by imitation of a cellular protein.
Troy L Brady, Peter G Fuerst, Robert A Dick, Clarice Schmidt, Daniel F Voytas

Mol Cell Biol· February 2008

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Phosphorylation regulates integration of the yeast Ty5 retrotransposon into heterochromatin.
Junbiao Dai, Weiwu Xie, Troy L Brady, Jiquan Gao, Daniel F Voytas

Mol Cell· July 2007

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