Publications by authors named "Ty Gould"

Claim this Profile
O
Optimization of 3-Pyrimidin-4-yl-oxazolidin-2-ones as Orally Bioavailable and Brain Penetrant Mutant IDH1 Inhibitors.
Qian Zhao, James R Manning, James Sutton, Abran Costales, Martin Sendzik, Ty Gould

ACS Med Chem Lett· July 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery and Evaluation of Clinical Candidate IDH305, a Brain Penetrant Mutant IDH1 Inhibitor.
Young Shin Cho, Julian R Levell, Gang Liu, Thomas Caferro, James Sutton, Ty Gould

ACS Med Chem Lett· October 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Optimization of 3-Pyrimidin-4-yl-oxazolidin-2-ones as Allosteric and Mutant Specific Inhibitors of IDH1.
Julian R Levell, Thomas Caferro, Gregg Chenail, Ina Dix, Julia Dooley, Ty Gould

ACS Med Chem Lett· February 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Small-molecule factor D inhibitors targeting the alternative complement pathway.
Jürgen Maibaum, Sha-Mei Liao, Anna Vulpetti, Nils Ostermann, Stefan Randl, Ty Gould

Nat Chem Biol· December 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Implementation of pharmacokinetic and pharmacodynamic strategies in early research phases of drug discovery and development at Novartis Institute of Biomedical Research.
Tove Tuntland, Brian Ethell, Takatoshi Kosaka, Francesca Blasco, Richard Xu Zang, Ty Gould

Front Pharmacol· August 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure-efficiency relationship of [1,2,4]triazol-3-ylamines as novel nicotinamide isosteres that inhibit tankyrases.
Michael D Shultz, Dyuti Majumdar, Donovan N Chin, Pascal D Fortin, Yun Feng, Ty Gould

J Med Chem· September 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of NVP-TNKS656: the use of structure-efficiency relationships to generate a highly potent, selective, and orally active tankyrase inhibitor.
Michael D Shultz, Atwood K Cheung, Christina A Kirby, Brant Firestone, Jianmei Fan, Ty Gould

J Med Chem· August 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Defective autophagy and mTORC1 signaling in myotubularin null mice.
Kristina M Fetalvero, Yenyen Yu, Margaret Goetschkes, Guiqing Liang, Reginald A Valdez, Ty Gould

Mol Cell Biol· January 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Dual role of isocitrate lyase 1 in the glyoxylate and methylcitrate cycles in Mycobacterium tuberculosis.
Ty A Gould, Helmus van de Langemheen, Ernesto J Muñoz-Elías, John D McKinney, James C Sacchettini

Mol Microbiol· August 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Tumor targeting by an aptamer.
Brian J Hicke, Andrew W Stephens, Ty Gould, Ying-Fon Chang, Cynthia K Lynott

J Nucl Med· April 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Specificity of acyl-homoserine lactone synthases examined by mass spectrometry.
Ty A Gould, Jake Herman, Jessica Krank, Robert C Murphy, Mair E A Churchill

J Bacteriol· January 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
Q
Quorum-sensing signal synthesis by the Yersinia pestis acyl-homoserine lactone synthase YspI.
J Paul Kirwan, Ty A Gould, Herbert P Schweizer, Scott W Bearden, Robert C Murphy

J Bacteriol· January 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure of the Pseudomonas aeruginosa acyl-homoserinelactone synthase LasI.
Ty A Gould, Herbert P Schweizer, Mair E A Churchill

Mol Microbiol· August 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Crystallization of Pseudomonas aeruginosa AHL synthase LasI using beta-turn crystal engineering.
Ty A Gould, William T Watson, Kyoung Hee Choi, Herbert P Schweizer, Mair E A Churchill

Acta Crystallogr D Biol Crystallogr· March 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis