Publications by authors named "Tyani Chan"

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B
BAFFR controls early memory B cell responses but is dispensable for germinal center function.
Angelica W Y Lau, Vivian M Turner, Katherine Bourne, Jana R Hermes, Tyani D Chan

J Exp Med· February 2021

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Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination.
Deborah L Burnett, David B Langley, Peter Schofield, Jana R Hermes, Tyani D Chan

Science· April 2018

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Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells.
Nike J Kräutler, Dan Suan, Danyal Butt, Katherine Bourne, Jana R Hermes, Tyani D Chan

J Exp Med· May 2017

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IL-21 and IL-4 Collaborate To Shape T-Dependent Antibody Responses.
Helen M McGuire, Alexis Vogelzang, Joanna Warren, Claudia Loetsch, Karlo D Natividad, Tyani D Chan

J Immunol· December 2015

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FAS Inactivation Releases Unconventional Germinal Center B Cells that Escape Antigen Control and Drive IgE and Autoantibody Production.
Danyal Butt, Tyani D Chan, Katherine Bourne, Jana R Hermes, Akira Nguyen

Immunity· May 2015

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Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity.
Zahra Sabouri, Peter Schofield, Keisuke Horikawa, Emily Spierings, David Kipling, Tyani D Chan

Proc Natl Acad Sci U S A· June 2014

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Elimination of germinal-center-derived self-reactive B cells is governed by the location and concentration of self-antigen.
Tyani D Chan, Katherine Wood, Jana R Hermes, Danyal Butt, Christopher J Jolly

Immunity· November 2012

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Affinity-based selection and the germinal center response.
Tyani D Chan, Robert Brink

Immunol Rev· May 2012

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B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells.
Sau K Lee, Robert J Rigby, Dimitra Zotos, Louis M Tsai, Shimpei Kawamoto, Tyani D Chan

J Exp Med· July 2011

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In vivo control of B-cell survival and antigen-specific B-cell responses.
Tyani D Chan, Sandra Gardam, Dominique Gatto, Vivian M Turner, John Silke

Immunol Rev· September 2010

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B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans.
Danielle T Avery, Elissa K Deenick, Cindy S Ma, Santi Suryani, Nicholas Simpson, Tyani D Chan

J Exp Med· January 2010

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Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production.
Katrina L Randall, Teresa Lambe, Andy L Johnson, Bebhinn Treanor, Edyta Kucharska, Tyani D Chan

Nat Immunol· December 2009

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Antigen affinity controls rapid T-dependent antibody production by driving the expansion rather than the differentiation or extrafollicular migration of early plasmablasts.
Tyani D Chan, Dominique Gatto, Katherine Wood, Tahra Camidge, Antony Basten

J Immunol· September 2009

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Visualizing the effects of antigen affinity on T-dependent B-cell differentiation.
Robert Brink, Tri Giang Phan, Didrik Paus, Tyani D Chan

Immunol Cell Biol· January 2008

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High affinity germinal center B cells are actively selected into the plasma cell compartment.
Tri Giang Phan, Didrik Paus, Tyani D Chan, Marian L Turner, Stephen L Nutt

J Exp Med· October 2006

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Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation.
Didrik Paus, Tri Giang Phan, Tyani D Chan, Sandra Gardam, Antony Basten

J Exp Med· April 2006

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Tumor necrosis factor receptor 2 (TNFR2) signaling is negatively regulated by a novel, carboxyl-terminal TNFR-associated factor 2 (TRAF2)-binding site.
Adrian P Grech, Sandra Gardam, Tyani Chan, Rachel Quinn, Ruth Gonzales

J Biol Chem· September 2005

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TRAF2 differentially regulates the canonical and noncanonical pathways of NF-kappaB activation in mature B cells.
Adrian P Grech, Michelle Amesbury, Tyani Chan, Sandra Gardam, Antony Basten

Immunity· November 2004

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