Publications by authors named "Uday Saxena"

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Novel nanobody drug conjugate as a prophylactic or therapeutic against SARS-CoV-2 infection in mice.
Brian Imbiakha, Shahrzad Ezzatpour, David W Buchholz, Suresh Poosala, Bharadwaja Vadloori, Uday Saxena

Biochem Biophys Res Commun· March 2025

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Advances in Animal Models and Cutting-Edge Research in Alternatives: Proceedings of the Second International Conference on 3Rs Research and Progress, Hyderabad, 2021.
Akshay Sonawane, Bharadwaja Vadloori, Suresh Poosala, Helena Kandarova, Mandar Kulkarni, Uday Saxena

Altern Lab Anim· March 2022

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A DNAzyme based knockdown model for Fragile-X syndrome in zebrafish reveals a critical window for therapeutic intervention.
Raghavender Medishetti, Rita Rani, Srinivas Kavati, Anjali Mahilkar, Venkateswarlu Akella, Uday Saxena

J Pharmacol Toxicol Methods· November 2020

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Statins exacerbate glucose intolerance and hyperglycemia in a high sucrose fed rodent model.
Sriram Seshadri, Naimisha Rapaka, Bhumika Prajapati, Dipeeka Mandaliya, Sweta Patel, Uday Saxena

Sci Rep· June 2019

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Magnetic nanoparticle formulation for targeted delivery of chemotherapeutic irinotecan to lungs.
Pushkar Kulkarni, Marina Rajadurai, Aarti Sevilimedu, Surendar Basaveni, Swapna Yellanki, Uday Saxena

Drug Deliv Transl Res· October 2018

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Correlation of pharmacokinetics and brain penetration data of adult zebrafish with higher mammals including humans.
Pushkar Kulkarni, Raghavender Medishetti, Nagaraju Nune, Swapna Yellanki, Vijaykumar Sripuram, Uday Saxena

J Pharmacol Toxicol Methods· July 2018

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Novel Zebrafish EAE model: A quick in vivo screen for multiple sclerosis.
Pushkar Kulkarni, Swapna Yellanki, Raghavender Medishetti, Dharmarajan Sriram, Uday Saxena

Mult Scler Relat Disord· January 2017

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Simvastatin may induce insulin resistance through a novel fatty acid mediated cholesterol independent mechanism.
Vasundhara Kain, Bandish Kapadia, Parimal Misra, Uday Saxena

Sci Rep· September 2015

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Investigational drugs for the management of Huntington's disease: are we there yet?
Pushkar Kulkarni, Uday Saxena

Expert Opin Investig Drugs· December 2014

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Head and neck cancers, the neglected malignancies: present and future treatment strategies.
Pushkar Kulkarni, Uday Saxena

Expert Opin Ther Targets· April 2014

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Bioenergetics failure in neurodegenerative diseases: back to the future.
Uday Saxena

Expert Opin Ther Targets· April 2012

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Bioenergetics breakdown in Alzheimer's disease: targets for new therapies.
Uday Saxena

Int J Physiol Pathophysiol Pharmacol· November 2011

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Alzheimer's disease amyloid hypothesis at crossroads: where do we go from here?
Uday Saxena

Expert Opin Ther Targets· December 2010

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Lipoic acid synthase (LASY): a novel role in inflammation, mitochondrial function, and insulin resistance.
Indira Padmalayam, Sumera Hasham, Uday Saxena, Sivaram Pillarisetti

Diabetes· March 2009

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Lipid metabolism and Alzheimer's disease: pathways and possibilities.
Uday Saxena

Expert Opin Ther Targets· March 2009

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Serum levels of interleukin 6, C-reactive protein, vascular cell adhesion molecule 1, and monocyte chemotactic protein 1 in relation to insulin resistance and glucose intolerance--the Chennai Urban Rural Epidemiology Study (CURES).
Raj Deepa, Kaliyaperumal Velmurugan, Kannan Arvind, Pillarisetti Sivaram, Cahoon Sientay, Saxena Uday

Metabolism· September 2006

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Novel anti-inflammatory role for glycogen synthase kinase-3beta in the inhibition of tumor necrosis factor-alpha- and interleukin-1beta-induced inflammatory gene expression.
Angela Vines, Sientay Cahoon, Ira Goldberg, Uday Saxena, Sivaram Pillarisetti

J Biol Chem· June 2006

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A new therapeutic target for atherosclerosis treatment: interview with Uday Saxena. Interviewed by Emma Quigley.
Uday Saxena

Expert Opin Ther Targets· February 2006

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Discovery of novel phenolic antioxidants as inhibitors of vascular cell adhesion molecule-1 expression for use in chronic inflammatory diseases.
Charles Q Meng, Patricia K Somers, Lee K Hoong, X Sharon Zheng, Zhihong Ye, Uday Saxena

J Med Chem· December 2004

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Atherosclerosis -- new targets and therapeutics.
Sivaram Pillarisetti, Christopher W Alexander, Uday Saxena

Curr Med Chem Cardiovasc Hematol Agents· October 2004

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Role of oxidative stress and inflammation in the origin of Type 2 diabetes--a paradigm shift.
Sivaram Pillarisetti, Uday Saxena

Expert Opin Ther Targets· October 2004

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Inflammatory cytokines and fatty acids regulate endothelial cell heparanase expression.
Guangping Chen, Dongyan Wang, Reeba Vikramadithyan, Hiroaki Yagyu, Uday Saxena

Biochemistry· May 2004

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Selective inhibition of endothelial and monocyte redox-sensitive genes by AGI-1067: a novel antioxidant and anti-inflammatory agent.
Charles Kunsch, Jayraz Luchoomun, Janice Y Grey, Lynda K Olliff, Leigh B Saint, Uday Saxena

J Pharmacol Exp Ther· March 2004

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AGI-1067: a multifunctional phenolic antioxidant, lipid modulator, anti-inflammatory and antiatherosclerotic agent.
Cynthia L Sundell, Patricia K Somers, Charles Q Meng, Lee K Hoong, Ki-Ling Suen, Uday Saxena

J Pharmacol Exp Ther· June 2003

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Lead discovery of alpha,beta-unsaturated sulfones from a combinatorial library as inhibitors of inducible VCAM-1 expression.
Liming Ni, X Sharon Zheng, Patricia K Somers, Lee K Hoong, Russell R Hill, Uday Saxena

Bioorg Med Chem Lett· February 2003

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