Publications by authors named "Ulrike Bartz"

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Redirecting the Peptide Cleavage Causes Protease Inactivation.
Christian Breuer, Jim Küppers, Anna-Christina Schulz-Fincke, Anna Heilos, Carina Lemke, Ulrike Bartz

Angew Chem Int Ed Engl· July 2025

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Development of an active-site titrant for SARS-CoV-2 main protease as an indispensable tool for evaluating enzyme kinetics.
Rabea Voget, Julian Breidenbach, Tobias Claff, Alexandra Hingst, Katharina Sylvester, Ulrike Bartz

Acta Pharm Sin B· May 2024

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Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes.
Jakub Benýšek, Michal Buša, Petra Rubešová, Jindřich Fanfrlík, Martin Lepšík, Ulrike Bartz

J Enzyme Inhib Med Chem· December 2022

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The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer Agents.
Tim Keuler, Carina Lemke, Paul W Elsinghorst, Isabel Iriepa, Mourad Chioua, Ulrike Bartz

ACS Pharmacol Transl Sci· November 2022

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An Activity-Based Probe for Cathepsin K Imaging with Excellent Potency and Selectivity.
Carina Lemke, Jakub Benýšek, Dominik Brajtenbach, Christian Breuer, Adéla Jílková, Ulrike Bartz

J Med Chem· September 2021

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Coumarin as a structural component of substrates and probes for serine and cysteine proteases.
Julian Breidenbach, Ulrike Bartz, Michael Gütschow

Biochim Biophys Acta Proteins Proteom· September 2020

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Carbachol dimers with primary carbamate groups as homobivalent modulators of muscarinic receptors.
Rosanna Matucci, Cristina Bellucci, Maria Vittoria Martino, Marta Nesi, Dina Manetti, Ulrike Bartz

Eur J Pharmacol· September 2020

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N-Sulfonyl dipeptide nitriles as inhibitors of human cathepsin S: In silico design, synthesis and biochemical characterization.
Carina Lemke, Lorenzo Cianni, Christian Feldmann, Erik Gilberg, Jiafei Yin, Ulrike Bartz

Bioorg Med Chem Lett· September 2020

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Chromenones as Multineurotargeting Inhibitors of Human Enzymes.
Carina Lemke, Joscha Christmann, Jiafei Yin, José M Alonso, Estefanía Serrano, Ulrike Bartz

ACS Omega· December 2019

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Cathepsin B: Active site mapping with peptidic substrates and inhibitors.
Janina Schmitz, Erik Gilberg, Reik Löser, Jürgen Bajorath, Ulrike Bartz

Bioorg Med Chem· January 2019

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Synthesis and kinetic evaluation of ethyl acrylate and vinyl sulfone derived inhibitors for human cysteine cathepsins.
Christian Breuer, Carina Lemke, Janina Schmitz, Ulrike Bartz, Michael Gütschow

Bioorg Med Chem Lett· June 2018

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Cathepsin B Inhibitors: Combining Dipeptide Nitriles with an Occluding Loop Recognition Element by Click Chemistry.
Janina Schmitz, Tianwei Li, Ulrike Bartz, Michael Gütschow

ACS Med Chem Lett· March 2016

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Design, characterization and cellular uptake studies of fluorescence-labeled prototypic cathepsin inhibitors.
Franziska Kohl, Janina Schmitz, Norbert Furtmann, Anna-Christina Schulz-Fincke, Matthias D Mertens, Ulrike Bartz

Org Biomol Chem· November 2015

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Active Site Mapping of Human Cathepsin F with Dipeptide Nitrile Inhibitors.
Janina Schmitz, Norbert Furtmann, Moritz Ponert, Maxim Frizler, Reik Löser, Ulrike Bartz

ChemMedChem· August 2015

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3-Cyano-3-aza-β-amino Acid Derivatives as Inhibitors of Human Cysteine Cathepsins.
Janina Schmitz, Anna-Madeleine Beckmann, Adela Dudic, Tianwei Li, Robert Sellier, Ulrike Bartz

ACS Med Chem Lett· October 2014

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Steroidal isomers with uniform mass spectra of their per-TMS derivatives: synthesis of 17-hydroxyandrostan-3-ones, androst-1-, and -4-ene-3,17-diols.
Maria K Parr, Josef Zapp, Michael Becker, Georg Opfermann, Ulrike Bartz

Steroids· June 2007

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