Publications by authors named "Ursula R Kees"

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Targeting osteoclasts for treatment of high-risk B-cell acute lymphoblastic leukemia.
Rishi S Kotecha, Sarah M Trinder, Anastasia M Hughes, Benjamin H Mullin, Sarah Rashid, Ursula R Kees

Blood Cancer J· February 2025

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Preclinical efficacy of azacitidine and venetoclax for infant KMT2A-rearranged acute lymphoblastic leukemia reveals a new therapeutic strategy.
Laurence C Cheung, Carlos Aya-Bonilla, Mark N Cruickshank, Sung K Chiu, Vincent Kuek, Ursula R Kees

Leukemia· January 2023

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Exploiting the reactive oxygen species imbalance in high-risk paediatric acute lymphoblastic leukaemia through auranofin.
Mawar Karsa, Angelika Kosciolek, Angelika Bongers, Anna Mariana, Tim Failes, Ursula R Kees

Br J Cancer· July 2021

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Incidence of NUT carcinoma in Western Australia from 1989 to 2014: a review of pediatric and adolescent cases from Perth Children's Hospital.
Tina Carter, Maxine Crook, Ashleigh Murch, Alex H Beesley, Nick de Klerk, Ursula R Kees

BMC Cancer· June 2021

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Preclinical Evaluation of Carfilzomib for Infant -Rearranged Acute Lymphoblastic Leukemia.
Laurence C Cheung, Rebecca de Kraa, Joyce Oommen, Grace-Alyssa Chua, Sajla Singh, Ursula R Kees

Front Oncol· April 2021

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The bone marrow microenvironment of pre-B acute lymphoblastic leukemia at single-cell resolution.
Denise Anderson, Patrycja Skut, Anastasia M Hughes, Emanuela Ferrari, Jennifer Tickner, Ursula R Kees

Sci Rep· November 2020

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Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia.
Klaartje Somers, Kathryn Evans, Leanna Cheung, Mawar Karsa, Tara Pritchard, Ursula R Kees

Leukemia· June 2020

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Potent antileukemic activity of curaxin CBL0137 against MLL-rearranged leukemia.
Klaartje Somers, Angelika Kosciolek, Angelika Bongers, Ali El-Ayoubi, Mawar Karsa, Ursula R Kees

Int J Cancer· April 2020

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Romidepsin enhances the efficacy of cytarabine , revealing histone deacetylase inhibition as a promising therapeutic strategy for -rearranged infant acute lymphoblastic leukemia.
Laurence C Cheung, Mark N Cruickshank, Anastasia M Hughes, Sajla Singh, Grace-Alyssa Chua, Ursula R Kees

Haematologica· July 2019

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A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction.
Klaartje Somers, Victoria W Wen, Shiloh M C Middlemiss, Brenna Osborne, Helen Forgham, Ursula R Kees

Oncogene· May 2019

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New therapeutic opportunities from dissecting the pre-B leukemia bone marrow microenvironment.
Laurence C Cheung, Jennifer Tickner, Anastasia M Hughes, Patrycja Skut, Meegan Howlett, Ursula R Kees

Leukemia· November 2018

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Molecular-genetic profiling and high-throughput drug screening in NUT midline carcinoma-an aggressive and fatal disease.
Anja Stirnweiss, Joyce Oommen, Rishi S Kotecha, Ursula R Kees, Alex H Beesley

Oncotarget· December 2017

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Heterogeneity in mechanisms of emergent resistance in pediatric T-cell acute lymphoblastic leukemia.
Babasaheb D Yadav, Amy L Samuels, Julia E Wells, Rosemary Sutton, Nicola C Venn, Ursula R Kees

Oncotarget· September 2016

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CCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements.
Klaartje Somers, Daria A Chudakova, Shiloh M C Middlemiss, Victoria W Wen, Molly Clifton, Ursula R Kees

Oncotarget· July 2016

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Gene expression analyses of the spatio-temporal relationships of human medulloblastoma subgroups during early human neurogenesis.
Cornelia M Hooper, Susan M Hawes, Ursula R Kees, Nicholas G Gottardo, Peter B Dallas

PLoS One· December 2015

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The role of CCN family genes in haematological malignancies.
J E Wells, M Howlett, L C Cheung, Ursula R Kees

J Cell Commun Signal· September 2015

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Deregulated expression of connective tissue growth factor (CTGF/CCN2) is linked to poor outcome in human cancer.
Julia E Wells, Meegan Howlett, Catherine H Cole, Ursula R Kees

Int J Cancer· August 2015

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Rare childhood cancers--an increasing entity requiring the need for global consensus and collaboration.
Rishi S Kotecha, Ursula R Kees, Catherine H Cole, Nicholas G Gottardo

Cancer Med· June 2015

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Effective targeting of the P53-MDM2 axis in preclinical models of infant MLL-rearranged acute lymphoblastic leukemia.
Jennifer Richmond, Hernan Carol, Kathryn Evans, Laura High, Agnes Mendomo, Ursula R Kees

Clin Cancer Res· March 2015

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Aberrant expression of aldehyde dehydrogenase 1A (ALDH1A) subfamily genes in acute lymphoblastic leukaemia is a common feature of T-lineage tumours.
Brooke A C Longville, Denise Anderson, Mathew D Welch, Ursula R Kees, Wayne K Greene

Br J Haematol· January 2015

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Germ-line and somatic DICER1 mutations in pineoblastoma.
Leanne de Kock, Nelly Sabbaghian, Harriet Druker, Evan Weber, Nancy Hamel, Ursula R Kees

Acta Neuropathol· October 2014

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Connective tissue growth factor is expressed in bone marrow stromal cells and promotes interleukin-7-dependent B lymphopoiesis.
Laurence C Cheung, Deborah H Strickland, Meegan Howlett, Jette Ford, Adrian K Charles, Ursula R Kees

Haematologica· July 2014

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Bioenergetic modulation overcomes glucocorticoid resistance in T-lineage acute lymphoblastic leukaemia.
Amy L Samuels, Jasmin Y Heng, Alex H Beesley, Ursula R Kees

Br J Haematol· April 2014

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Hypomethylation of the CTGF gene locus is a common feature of paediatric pre-B acute lymphoblastic leukaemia.
Mathew D Welch, Wayne K Greene, Ursula R Kees

Br J Haematol· August 2013

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Drug-gene modeling in pediatric T-cell acute lymphoblastic leukemia highlights importance of 6-mercaptopurine for outcome.
Alex H Beesley, Martin J Firth, Denise Anderson, Amy L Samuels, Jette Ford, Ursula R Kees

Cancer Res· May 2013

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