Publications by authors named "Valentin Grabovsky"

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Development of Novel Promiscuous Anti-Chemokine Peptibodies for Treating Autoimmunity and Inflammation.
Michal Abraham, Hanna Wald, Dalit Vaizel-Ohayon, Valentin Grabovsky, Zohar Oren

Front Immunol· November 2017

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CD151 Regulates T-Cell Migration in Health and Inflammatory Bowel Disease.
Einat Zelman-Toister, Eszter Bakos, Sivan Cohen, Ehud Zigmond, Elias Shezen, Valentin Grabovsky

Inflamm Bowel Dis· February 2016

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Loss of kindlin-3 alters the threshold for NK cell activation in human leukocyte adhesion deficiency-III.
Raizy Gruda, Alice C N Brown, Valentin Grabovsky, Saar Mizrahi, Chamutal Gur

Blood· November 2012

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Transendothelial migration of lymphocytes mediated by intraendothelial vesicle stores rather than by extracellular chemokine depots.
Ziv Shulman, Shmuel J Cohen, Ben Roediger, Vyacheslav Kalchenko, Rohit Jain, Valentin Grabovsky

Nat Immunol· December 2011

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Kindlin-3 is required for the stabilization of TCR-stimulated LFA-1:ICAM-1 bonds critical for lymphocyte arrest and spreading on dendritic cells.
Sara W Feigelson, Valentin Grabovsky, Eugenia Manevich-Mendelson, Ronit Pasvolsky, Ziv Shulman

Blood· June 2011

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Talin1 is required for integrin-dependent B lymphocyte homing to lymph nodes and the bone marrow but not for follicular B-cell maturation in the spleen.
Eugenia Manevich-Mendelson, Valentin Grabovsky, Sara W Feigelson, Guy Cinamon, Yael Gore

Blood· December 2010

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Occupancy of lymphocyte LFA-1 by surface-immobilized ICAM-1 is critical for TCR- but not for chemokine-triggered LFA-1 conversion to an open headpiece high-affinity state.
Sara W Feigelson, Ronit Pasvolsky, Saso Cemerski, Ziv Shulman, Valentin Grabovsky

J Immunol· December 2010

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TAp63 regulates VLA-4 expression and chronic lymphocytic leukemia cell migration to the bone marrow in a CD74-dependent manner.
Inbal Binsky, Frida Lantner, Valentin Grabovsky, Nurit Harpaz, Lev Shvidel

J Immunol· May 2010

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Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions.
Eugenia Manevich-Mendelson, Sara W Feigelson, Ronit Pasvolsky, Memet Aker, Valentin Grabovsky

Blood· September 2009

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Beta-arrestin 2 is required for the induction and strengthening of integrin-mediated leukocyte adhesion during CXCR2-driven extravasation.
Raffaella Molteni, Carolina Lage Crespo, Sara Feigelson, Christian Moser, Monica Fabbri, Valentin Grabovsky

Blood· July 2009

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Circulating B-cell chronic lymphocytic leukemia cells display impaired migration to lymph nodes and bone marrow.
Tanja Nicole Hartmann, Valentin Grabovsky, Wei Wang, Petra Desch, Gabriele Rubenzer

Cancer Res· April 2009

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Lymphocyte crawling and transendothelial migration require chemokine triggering of high-affinity LFA-1 integrin.
Ziv Shulman, Vera Shinder, Eugenia Klein, Valentin Grabovsky, Orna Yeger

Immunity· March 2009

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Anti-inflammatory effects of an inflammatory chemokine: CCL2 inhibits lymphocyte homing by modulation of CCL21-triggered integrin-mediated adhesions.
Liat Flaishon, Gili Hart, Einat Zelman, Christine Moussion, Valentin Grabovsky

Blood· December 2008

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A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells.
Tanja Nicole Hartmann, Valentin Grabovsky, Ronit Pasvolsky, Ziv Shulman, Eike C Buss

J Leukoc Biol· October 2008

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RhoA is involved in LFA-1 extension triggered by CXCL12 but not in a novel outside-in LFA-1 activation facilitated by CXCL9.
Ronit Pasvolsky, Valentin Grabovsky, Cinzia Giagulli, Ziv Shulman, Revital Shamri

J Immunol· March 2008

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Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces.
Eilon Woolf, Irina Grigorova, Adi Sagiv, Valentin Grabovsky, Sara W Feigelson

Nat Immunol· October 2007

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Talin 1 and paxillin facilitate distinct steps in rapid VLA-4-mediated adhesion strengthening to vascular cell adhesion molecule 1.
Eugenia Manevich, Valentin Grabovsky, Sara W Feigelson, Ronen Alon

J Biol Chem· August 2007

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A LAD-III syndrome is associated with defective expression of the Rap-1 activator CalDAG-GEFI in lymphocytes, neutrophils, and platelets.
Ronit Pasvolsky, Sara W Feigelson, Sara Sebnem Kilic, Amos J Simon, Guy Tal-Lapidot, Valentin Grabovsky

J Exp Med· July 2007

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Membranal cholesterol is not required for L-selectin adhesiveness in primary lymphocytes but controls a chemokine-induced destabilization of L-selectin rolling adhesions.
Oren Dwir, Valentin Grabovsky, Ronit Pasvolsky, Eugenia Manevich, Revital Shamri

J Immunol· July 2007

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DOCK2 regulates chemokine-triggered lateral lymphocyte motility but not transendothelial migration.
Ziv Shulman, Ronit Pasvolsky, Eilon Woolf, Valentin Grabovsky, Sara W Feigelson

Blood· October 2006

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Role of CXCR3 carboxyl terminus and third intracellular loop in receptor-mediated migration, adhesion and internalization in response to CXCL11.
Michal Dagan-Berger, Rotem Feniger-Barish, Shani Avniel, Hanna Wald, Eithan Galun, Valentin Grabovsky

Blood· May 2006

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Alpha4beta1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the alpha4-cytoplasmic domain.
Ronen Alon, Sara W Feigelson, Eugenia Manevich, David M Rose, Julia Schmitz, Valentin Grabovsky

J Cell Biol· December 2005

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Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokines.
Revital Shamri, Valentin Grabovsky, Jean-Marc Gauguet, Sara Feigelson, Eugenia Manevich

Nat Immunol· May 2005

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Enzymatically quiescent heparanase augments T cell interactions with VCAM-1 and extracellular matrix components under versatile dynamic contexts.
Ilya Sotnikov, Rami Hershkoviz, Valentin Grabovsky, Neta Ilan, Liora Cahalon

J Immunol· May 2004

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Differential usage of VLA-4 and CXCR4 by CD3+CD56+ NKT cells and CD56+CD16+ NK cells regulates their interaction with endothelial cells.
Suzanna Franitza, Valentin Grabovsky, Ori Wald, Ido Weiss, Katia Beider

Eur J Immunol· May 2004

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