Publications by authors named "Sivan Cohen"

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Effectorless Fc-fusion improves FLT3L drug-like properties for cancer immunotherapy combinations.
Jérémie Decalf, Evangeline Toy, Dongping He, Radhika Kenkre, Amy M Berkley, Sivan Cohen

EBioMedicine· August 2025

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A single point mutation on FLT3L-Fc protein increases the risk of immunogenicity.
Dan Qin, Qui Phung, Patrick Wu, Zhaojun Yin, Sien Tam, Sivan Cohen

Front Immunol· May 2025

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Nonclinical immunogenicity risk assessment for knobs-into-holes bispecific IgG antibodies.
Wen-Ting K Tsai, Yinyin Li, Zhaojun Yin, Peter Tran, Qui Phung, Sivan Cohen

MAbs· June 2024

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Reducing Immunogenicity by Design: Approaches to Minimize Immunogenicity of Monoclonal Antibodies.
Chantal T Harris, Sivan Cohen

BioDrugs· March 2024

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Graph-pMHC: graph neural network approach to MHC class II peptide presentation and antibody immunogenicity.
William John Thrift, Jason Perera, Sivan Cohen, Nicolas W Lounsbury, Hem R Gurung

Brief Bioinform· March 2024

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Application of N-Terminal Site-Specific Biotin and Digoxigenin Conjugates to Clinical Anti-drug Antibody Assay Development.
Xiangdan Wang, Wenping Chang, Mehraban Khosraviani, Wilson Phung, Lingling Peng, Sivan Cohen

Bioconjug Chem· February 2024

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The immunogenicity of human-origin therapeutic antibodies are associated with V gene usage.
Zicheng Hu, Sivan Cohen, Steven J Swanson

Front Immunol· September 2023

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A BCMA/CD16A bispecific innate cell engager for the treatment of multiple myeloma.
Satoko Kakiuchi-Kiyota, Thorsten Ross, Heidi Ackerly Wallweber, James R Kiefer, Melissa M Schutten, Sivan Cohen

Leukemia· April 2022

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An integrated approach for characterizing immunogenic responses toward a bispecific antibody.
Sivan Cohen, Shan Chung, Christoph Spiess, Victor Lundin, Eric Stefanich

MAbs· December 2021

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Immunogenicity risk assessment for biotherapeutics through in vitro detection of CD134 and CD137 on T helper cells.
Sivan Cohen, Srividya Myneni, Anna Batt, Joyce Guerrero, Jochen Brumm

MAbs· November 2021

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immunogenicity prediction: bridging between innate and adaptive immunity.
Sivan Cohen, Shan Chung

Bioanalysis· July 2021

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T Cells Regulate Peripheral Naive Mature B Cell Survival by Cell-Cell Contact Mediated through SLAMF6 and SAP.
Lihi Radomir, Sivan Cohen, Matthias P Kramer, Eszter Bakos, Hadas Lewinsky

J Immunol· October 2017

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CCR2 Regulates the Immune Response by Modulating the Interconversion and Function of Effector and Regulatory T Cells.
Eszter Bakos, Christoph A Thaiss, Matthias P Kramer, Sivan Cohen, Lihi Radomir

J Immunol· June 2017

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Nutritional effects on T-cell immunometabolism.
Sivan Cohen, Keiko Danzaki, Nancie J MacIver

Eur J Immunol· February 2017

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Foxp3 and Toll-like receptor signaling balance T cell anabolic metabolism for suppression.
Valerie A Gerriets, Rigel J Kishton, Marc O Johnson, Sivan Cohen, Peter J Siska

Nat Immunol· December 2016

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Suppression of Glut1 and Glucose Metabolism by Decreased Akt/mTORC1 Signaling Drives T Cell Impairment in B Cell Leukemia.
Peter J Siska, Gerritje J W van der Windt, Rigel J Kishton, Sivan Cohen, William Eisner

J Immunol· September 2016

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mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation.
Hu Zeng, Sivan Cohen, Cliff Guy, Sharad Shrestha, Geoffrey Neale

Immunity· September 2016

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AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival.
Rigel J Kishton, Carson E Barnes, Amanda G Nichols, Sivan Cohen, Valerie A Gerriets

Cell Metab· April 2016

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CD151 Regulates T-Cell Migration in Health and Inflammatory Bowel Disease.
Einat Zelman-Toister, Eszter Bakos, Sivan Cohen, Ehud Zigmond, Elias Shezen

Inflamm Bowel Dis· February 2016

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Midkine as a regulator of B cell survival in health and disease.
Sivan Cohen, Idit Shachar

Br J Pharmacol· February 2014

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Nek7 kinase accelerates microtubule dynamic instability.
Sivan Cohen, Adva Aizer, Yaron Shav-Tal, Amiel Yanai, Benny Motro

Biochim Biophys Acta· May 2013

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Deficiency of caspase recruitment domain family, member 11 (CARD11), causes profound combined immunodeficiency in human subjects.
Polina Stepensky, Baerbel Keller, Mary Buchta, Anne-Kathrin Kienzler, Orly Elpeleg, Sivan Cohen

J Allergy Clin Immunol· February 2013

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Cytokines as regulators of proliferation and survival of healthy and malignant peripheral B cells.
Sivan Cohen, Idit Shachar

Cytokine· October 2012

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Regulation of CLL survival by hypoxia-inducible factor and its target genes.
Idit Shachar, Sivan Cohen, Ayelet Marom, Shirly Becker-Herman

FEBS Lett· August 2012

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The cytokine midkine and its receptor RPTPζ regulate B cell survival in a pathway induced by CD74.
Sivan Cohen, Or-yam Shoshana, Einat Zelman-Toister, Nitsan Maharshak, Inbal Binsky-Ehrenreich

J Immunol· January 2012

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