Publications by authors named "Valentina Factor"

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Corrigendum to "Loss of c-Met signaling sensitizes hepatocytes to lipotoxicity and induces cholestatic liver damage by aggravating oxidative stress" [Toxicology 361-362 (2016) 39-48].
Luis E Gomez-Quiroz, Daekwan Seo, Yun-Han Lee, Mitsuteru Kitade, Timo Gaiser, Valentina M Factor

Toxicology· February 2026

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Topoisomerase III-beta protects from immune dysregulation and tumorigenesis.
Md Rasel Al Mahmud, Simone Andrea Baechler, Anjali Dhall, Sourav Saha, Hongliang Zhang, Valentina M Factor

Sci Adv· December 2025

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Topoisomerase IIIβ protects from tumorigenesis and immune dysregulation.
Md Rasel Al Mahmud, Simone Andrea Baechler, Anjali Dhall, Sourav Saha, Hongliang Zhang, Valentina M Factor

bioRxiv· March 2025

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Human chemically-derived hepatic progenitors (hCdHs) as a source of liver organoid generation: Application in regenerative medicine, disease modeling, and toxicology testing.
Soraya Salas-Silva, Yohan Kim, Tae Hun Kim, Myounghoi Kim, Daekwan Seo, Valentina M Factor

Biomaterials· December 2023

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Transplantation of patient-specific bile duct bioengineered with chemically reprogrammed and microtopographically differentiated cells.
Elina Maria Buisson, Suk-Hee Park, Myounghoi Kim, Kyojin Kang, Sangtae Yoon, Valentina M Factor

Bioeng Transl Med· January 2022

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Serum IL6 as a Prognostic Biomarker and IL6R as a Therapeutic Target in Biliary Tract Cancers.
Dan Høgdall, Colm J O'Rourke, Christian Dehlendorff, Ole F Larsen, Lars H Jensen, Valentina M Factor

Clin Cancer Res· November 2020

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Identification of a Pan-Gamma-Secretase Inhibitor Response Signature for Notch-Driven Cholangiocarcinoma.
Colm J O'Rourke, Matthias S Matter, Chirag Nepal, Rui Caetano-Oliveira, Phuongnga T Ton, Valentina M Factor

Hepatology· January 2020

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Reply to: "Role of HGF for reprogramming human liver progenitor cells: Non-essential but stimulative supplement".
Seung Bum Lee, Yohan Kim, Kyojin Kang, Valentina M Factor, Daekwan Seo

J Hepatol· August 2019

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c-Met Signaling Is Essential for Mouse Adult Liver Progenitor Cells Expansion After Transforming Growth Factor-β-Induced Epithelial-Mesenchymal Transition and Regulates Cell Phenotypic Switch.
Laura Almalé, María García-Álvaro, Adoración Martínez-Palacián, María García-Bravo, Nerea Lazcanoiturburu, Valentina M Factor

Stem Cells· August 2019

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Small molecule-mediated reprogramming of human hepatocytes into bipotent progenitor cells.
Yohan Kim, Kyojin Kang, Seung Bum Lee, Daekwan Seo, Sangtae Yoon, Valentina M Factor

J Hepatol· January 2019

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Integrated Genomic Comparison of Mouse Models Reveals Their Clinical Resemblance to Human Liver Cancer.
Sun Young Yim, Jae-Jun Shim, Ji-Hyun Shin, Yun Seong Jeong, Sang-Hee Kang, Valentina M Factor

Mol Cancer Res· November 2018

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Mitochondrial tyrosyl-DNA phosphodiesterase 2 and its TDP2 short isoform.
Shar-Yin N Huang, Ilaria Dalla Rosa, Stephanie A Michaels, David V Tulumello, Keli Agama, Valentina M Factor

EMBO Rep· March 2018

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Consecutive entosis stages in human substrate-dependent cultured cells.
Anastasiia S Garanina, Olga P Kisurina-Evgenieva, Maria V Erokhina, Elena A Smirnova, Valentina M Factor

Sci Rep· October 2017

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Plasma glutamate carboxypeptidase is a negative regulator in liver cancer metastasis.
Jae-Hye Lee, Hyun-Soo Cho, Jeong-Ju Lee, Soo Young Jun, Jun-Ho Ahn, Valentina M Factor

Oncotarget· November 2016

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DNMT1 is a required genomic regulator for murine liver histogenesis and regeneration.
Kosuke Kaji, Valentina M Factor, Jesper B Andersen, Marian E Durkin, Akira Tomokuni

Hepatology· August 2016

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Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype.
Matthias S Matter, Jens U Marquardt, Jesper B Andersen, Cristina Quintavalle, Nikolay Korokhov, Valentina M Factor

Hepatology· June 2016

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Loss of c-Met signaling sensitizes hepatocytes to lipotoxicity and induces cholestatic liver damage by aggravating oxidative stress.
Luis E Gomez-Quiroz, Daekwan Seo, Yun-Han Lee, Mitsuteru Kitade, Timo Gaiser, Valentina M Factor

Toxicology· June 2016

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Signal transducer and activator of transcription 3-mediated CD133 up-regulation contributes to promotion of hepatocellular carcinoma.
Cheolhee Won, Byung-Hak Kim, Eun Hee Yi, Kyung-Ju Choi, Eun-Kyung Kim, Valentina M Factor

Hepatology· October 2015

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Curcumin effectively inhibits oncogenic NF-κB signaling and restrains stemness features in liver cancer.
Jens U Marquardt, Luis Gomez-Quiroz, Lucrecia O Arreguin Camacho, Federico Pinna, Yun-Han Lee, Valentina M Factor

J Hepatol· September 2015

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Lack of mitochondrial topoisomerase I (TOP1mt) impairs liver regeneration.
Salim Khiati, Simone A Baechler, Valentina M Factor, Hongliang Zhang, Shar-yin N Huang

Proc Natl Acad Sci U S A· September 2015

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The methyltransferases enhancer of zeste homolog (EZH) 1 and EZH2 control hepatocyte homeostasis and regeneration.
Woo Kyun Bae, Keunsoo Kang, Ji Hoon Yu, Kyung Hyun Yoo, Valentina M Factor

FASEB J· May 2015

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MYC activates stem-like cell potential in hepatocarcinoma by a p53-dependent mechanism.
Hirofumi Akita, Jens U Marquardt, Marian E Durkin, Mitsuteru Kitade, Daekwan Seo, Valentina M Factor

Cancer Res· October 2014

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Antitumor effects in hepatocarcinoma of isoform-selective inhibition of HDAC2.
Yun-Han Lee, Daekwan Seo, Kyung-Ju Choi, Jesper B Andersen, Min-Ah Won, Valentina M Factor

Cancer Res· September 2014

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CLPTM1L promotes growth and enhances aneuploidy in pancreatic cancer cells.
Jinping Jia, Allen D Bosley, Abbey Thompson, Jason W Hoskins, Adam Cheuk, Valentina M Factor

Cancer Res· May 2014

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