Publications by authors named "Vera Ruda"

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Transcriptional changes in non-human primate tissues after intrathecal delivery of serotype 9 adeno-associated viral vector: Insights into organ toxicities.
Fumiaki Aihara, Matthew Mardo, Vera Ruda, Tony Del Rio, Karine Bigot

Mol Ther Methods Clin Dev· December 2025

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Genomic crosstalk between carbachol, a muscarinic receptor agonist, and the long-acting β-adrenoceptor agonist, indacaterol, in human airway epithelial cells.
Varuna Jayasinghe, Radhika Joshi, Taruna Joshi, Tamkeen U Paracha, Cora Kooi, Vera M Ruda

J Pharmacol Exp Ther· June 2025

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Single cell multi-omics reveals re-dosing with CD3 bispecific antibody induces a TCF7 high central memory CD8 + T cell population associated with reduced cytokine production.
Hui Ling, Lauren Anderson, Katie Kubek-Luck, Juliane Perner, Tyler Burks, Vera M Ruda

Biomed Pharmacother· May 2025

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Integrated analysis of the transcriptome and its interaction with the metabolome in metabolic associated fatty liver disease: Gut microbiome signatures, correlation networks, and effect of PNPLA3 genotype.
María Florencia Mascardi, Flavia Noelia Mazzini, Bárbara Suárez, Vera M Ruda, Sebastián Marciano

Proteomics· September 2023

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TGFβ-blockade uncovers stromal plasticity in tumors by revealing the existence of a subset of interferon-licensed fibroblasts.
Angelo L Grauel, Beverly Nguyen, David Ruddy, Tyler Laszewski, Stephanie Schwartz, Vera Ruda

Nat Commun· December 2020

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Pervasive Regulatory Functions of mRNA Structure Revealed by High-Resolution SHAPE Probing.
Anthony M Mustoe, Steven Busan, Greggory M Rice, Christine E Hajdin, Brant K Peterson, Vera M Ruda

Cell· March 2018

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Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination.
Hok Hei Tam, Mariane B Melo, Myungsun Kang, Jeisa M Pelet, Vera M Ruda

Proc Natl Acad Sci U S A· October 2016

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The roles of individual mammalian argonautes in RNA interference in vivo.
Vera M Ruda, Rohit Chandwani, Alfica Sehgal, Roman L Bogorad, Akin Akinc

PLoS One· May 2016

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RNAi-nanoparticulate manipulation of gene expression as a new functional genomics tool in the liver.
Hao Yin, Roman L Bogorad, Carmen Barnes, Stephen Walsh, Iris Zhuang, Vera Ruda

J Hepatol· April 2016

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Macrophages retain hematopoietic stem cells in the spleen via VCAM-1.
Partha Dutta, Friedrich Felix Hoyer, Lubov S Grigoryeva, Hendrik B Sager, Florian Leuschner, Vera M Ruda

J Exp Med· April 2015

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In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight.
James E Dahlman, Carmen Barnes, Omar Khan, Aude Thiriot, Siddharth Jhunjunwala, Vera M Ruda

Nat Nanotechnol· August 2014

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Nanoparticle-formulated siRNA targeting integrins inhibits hepatocellular carcinoma progression in mice.
Roman L Bogorad, Hao Yin, Anja Zeigerer, Hidenori Nonaka, Vera M Ruda

Nat Commun· May 2014

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Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice.
Jae-Seon So, Kyu Yeon Hur, Margarite Tarrio, Vera Ruda, Maria Frank-Kamenetsky

Cell Metab· October 2012

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Rab5 is necessary for the biogenesis of the endolysosomal system in vivo.
Anja Zeigerer, Jerome Gilleron, Roman L Bogorad, Giovanni Marsico, Hidenori Nonaka, Vera M Ruda

Nature· May 2012

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IRE1α activation protects mice against acetaminophen-induced hepatotoxicity.
Kyu Yeon Hur, Jae-Seon So, Vera Ruda, Maria Frank-Kamenetsky, Kevin Fitzgerald

J Exp Med· February 2012

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Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells.
Tatiana I Novobrantseva, Anna Borodovsky, Jamie Wong, Boris Klebanov, Mohammad Zafari, Vera M Ruda

Mol Ther Nucleic Acids· January 2012

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Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells.
Genc Basha, Tatiana I Novobrantseva, Nicole Rosin, Yuen Yi C Tam, Ismail M Hafez, Vera M Ruda

Mol Ther· December 2011

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From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus.
Kiran Musunuru, Alanna Strong, Maria Frank-Kamenetsky, Noemi E Lee, Tim Ahfeldt, Vera M Ruda

Nature· August 2010

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Caffeine prevents transcription inhibition and P-TEFb/7SK dissociation following UV-induced DNA damage.
Giuliana Napolitano, Stefano Amente, Virginia Castiglia, Barbara Gargano, Vera Ruda

PLoS One· June 2010

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Imaging transcription in living cells.
Xavier Darzacq, Jie Yao, Daniel R Larson, Sébastien Z Causse, Lana Bosanac, Vera M Ruda

Annu Rev Biophys· July 2009

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Identification, genome mapping, and CTCF binding of potential insulators within the FXYD5-COX7A1 locus of human chromosome 19q13.12.
Sergey B Akopov, Vera M Ruda, Vera V Batrak, Anna S Vetchinova, Igor P Chernov

Mamm Genome· October 2006

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