Publications by authors named "Vilhelm A Bohr"

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Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double-Blind Randomized Crossover Placebo-Controlled Trial.
Mayumi Shoji, Hisaya Kato, Masaya Koshizaka, Hiyori Kaneko, Yusuke Baba, Takahiro Ishikawa, Naoya Teramoto, Daisuke Kinoshita, Ayano Yamaguchi, Yukari Maeda

Aging Cell· August 2025

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Urolithin A improves Alzheimer's disease cognition and restores mitophagy and lysosomal functions.
Yujun Hou, Xixia Chu, Jae-Hyeon Park, Qing Zhu, Mansoor Hussain, Zhiquan Li, Helena Borland Madsen, Beimeng Yang, Yong Wei, Yue Wang

June 2024

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NAD supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency.
Yujun Hou, Sofie Lautrup, Stephanie Cordonnier, Yue Wang, Deborah L Croteau, Eduardo Zavala, Yongqing Zhang, Kanako Moritoh, Jennifer F O'Connell, Beverly A Baptiste

Proc Natl Acad Sci U S A· February 2018

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NAD in Aging: Molecular Mechanisms and Translational Implications.
Evandro F Fang, Sofie Lautrup, Yujun Hou, Tyler G Demarest, Deborah L Croteau, Mark P Mattson, Vilhelm A Bohr

October 2017

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Novel roles of DNA glycosylases in neurodegenerative diseases and aging.
Vinod Tiwari, Fivos Borbolis, Deborah L Croteau, Konstantinos Palikaras, Vilhelm A Bohr

Neural Regen Res· May 2026

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Cockayne syndrome mice reflect human kidney disease and are defective in de novo NAD biosynthesis.
Komal Pekhale, Vinod Tiwari, Mansoor Hussain, Christy C Bridges, Deborah L Croteau, Vilhelm A Bohr

Cell Death Differ· November 2025

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Spatial transcriptomics reveals an unexpected impact of tau and tau pathology on the expression of transthyretin.
Deborah L Croteau, Jose Fernandez Navarro, Thomas Comptdaer, Zaneta Andrusivova, Aleksandra Jurek, Vilhelm A Bohr

Front Aging Neurosci· November 2025

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Emerging strategies, applications and challenges of targeting NAD in the clinic.
Jianying Zhang, He-Ling Wang, Sofie Lautrup, Hilde Loge Nilsen, Jonas T Treebak, Vilhelm A Bohr

Nat Aging· September 2025

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Urolithin Α modulates inter-organellar communication via calcium-dependent mitophagy to promote healthy ageing.
Antonis Roussos, Katerina Kitopoulou, Fivos Borbolis, Christina Ploumi, Despoina D Gianniou, Vilhelm A Bohr

Autophagy· September 2025

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Selective interactions at pre-replication complexes categorize baseline and dormant origins.
Bhushan L Thakur, Christophe E Redon, Haiqing Fu, Robin Sebastian, Nana A Kusi, Vilhelm A Bohr

Nat Commun· May 2025

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Decreased mitochondrial NAD+ in WRN deficient cells links to dysfunctional proliferation.
Sofie Lautrup, Shi-Qi Zhang, Shinichiro Funayama, Lisa Lirussi, Tina Visnovska, Vilhelm A Bohr

Aging (Albany NY)· April 2025

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Editorial: Targeting the aging mitochondria: mechanisms, methods, and therapeutic strategies.
Zhiquan Li, Konstantinos Palikaras, Yuan Li, Vilhelm A Bohr

Front Aging Neurosci· March 2025

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RECQL4 requires PARP1 for recruitment to DNA damage, and PARG dePARylation facilitates its associated role in end joining.
Mansoor Hussain, Prabhat Khadka, Komal Pekhale, Tomasz Kulikowicz, Samuel Gray, Vilhelm A Bohr

Exp Mol Med· February 2025

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Mitochondrial accumulation and lysosomal dysfunction result in mitochondrial plaques in Alzheimer's disease.
Xiuli Dan, Deborah L Croteau, Wenlong Liu, Xixia Chu, Paul D Robbins, Vilhelm A Bohr

bioRxiv· February 2025

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Effect of Dietary Ketosis and Nicotinamide Riboside on Hippocampal Krebs Cycle Intermediates and Mitochondrial Energetics in a DNA Repair-Deficient 3xTg/POLβ Alzheimer Disease Mouse Model.
Robert Pawlosky, Tyler G Demarest, M Todd King, Darlene Estrada, Richard L Veech, Vilhelm A Bohr

J Neurochem· January 2025

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Urolithin A and nicotinamide riboside differentially regulate innate immune defenses and metabolism in human microglial cells.
Helena Borland Madsen, Claudia Navarro, Emilie Gasparini, Jae-Hyeon Park, Zhiquan Li, Vilhelm A Bohr

Front Aging Neurosci· November 2024

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Loss of DNA glycosylases improves health and cognitive function in a C. elegans model of human tauopathy.
Vinod Tiwari, Elisabeth Buvarp, Fivos Borbolis, Chandrakala Puligilla, Deborah L Croteau, Vilhelm A Bohr

Nucleic Acids Res· October 2024

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Nicotinamide riboside modulates the reactive species interactome, bioenergetic status and proteomic landscape in a brain-region-specific manner.
Alejandro Marmolejo-Garza, Laurent Chatre, Deborah L Croteau, Alejandro Herron-Bedoya, Minh Danh Anh Luu, Vilhelm A Bohr

Neurobiol Dis· October 2024

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Human fibroblasts from sporadic Alzheimer's disease (AD) patients show mitochondrial alterations and lysosome dysfunction.
Yuan Li, Zhiquan Li, Emanuela Grillo, Claus Desler, Claudia Navarro, Vilhelm A Bohr

Free Radic Biol Med· September 2024

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FOXO-regulated OSER1 reduces oxidative stress and extends lifespan in multiple species.
Jiangbo Song, Zhiquan Li, Lei Zhou, Xin Chen, Wei Qi Guinevere Sew, Vilhelm A Bohr

Nat Commun· August 2024

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Markers of Mitochondrial Function and DNA Repair Associated with Physical Function in Centenarians.
Ines Sanchez-Roman, Beatriz Ferrando, Camilla Myrup Holst, Jonas Mengel-From, Signe Hoei Rasmussen, Vilhelm A Bohr

Biomolecules· July 2024

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Salidroside promotes healthy longevity by interfering with HSP90 activity.
Jianfei Zhang, Zhiquan Li, Jiangbo Song, Lei Zhou, Xin Chen, Vilhelm A Bohr

Geroscience· April 2024

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Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies.
He-Ling Wang, Richard Siow, Tomas Schmauck-Medina, Jianying Zhang, Per Morten Sandset, Vilhelm A Bohr

J Gerontol A Biol Sci Med Sci· April 2024

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Early-Onset Hearing Loss in Mouse Models of Alzheimer's Disease and Increased DNA Damage in the Cochlea.
Jae-Hyeon Park, Burcin Duan Sahbaz, Komal Pekhale, Xixia Chu, Mustafa N Okur, Vilhelm A Bohr

Aging Biol· February 2024

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Roles of NAD in Health and Aging.
Sofie Lautrup, Yujun Hou, Evandro F Fang, Vilhelm A Bohr

Cold Spring Harb Perspect Med· January 2024

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The DNA repair enzyme, aprataxin, plays a role in innate immune signaling.
Helena B Madsen, Louise I Pease, Rebekah-Louise Scanlan, Mansour Akbari, Lene J Rasmussen, Vilhelm A Bohr

Front Aging Neurosci· December 2023

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deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD precursor nicotinamide riboside.
Sharath Anugula, Zhiquan Li, Yuan Li, Alexander Hendriksen, Peter Bjarn Christensen, Vilhelm A Bohr

Heliyon· June 2023

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