Publications by authors named "Vincent Sandanayaka"

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Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia.
Rosa Lapalombella, Qingxiang Sun, Katie Williams, Larissa Tangeman, Shruti Jha, Vincent Sandanayaka

Blood· November 2012

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Discovery of novel leukotriene A4 hydrolase inhibitors based on piperidine and piperazine scaffolds.
Vincent Sandanayaka, Bjorn Mamat, Nikhil Bhagat, Louis Bedell, Gudrun Halldorsdottir

Bioorg Med Chem Lett· May 2010

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Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis.
Vincent Sandanayaka, Bjorn Mamat, Rama K Mishra, Jennifer Winger, Michael Krohn

J Med Chem· January 2010

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Synthesis and activity of quinolinylmethyl P1' alpha-sulfone piperidine hydroxamate inhibitors of TACE.
Chunchun Zhang, Frank Lovering, Mark Behnke, Arie Zask, Vincent Sandanayaka

Bioorg Med Chem Lett· July 2009

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Synthesis and SAR of diazepine and thiazepine TACE and MMP inhibitors.
Arie Zask, Joshua Kaplan, XueMei Du, Gloria MacEwan, Vincent Sandanayaka

Bioorg Med Chem Lett· March 2005

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Synthesis and structure-activity relationship of N-substituted 4-arylsulfonylpiperidine-4-hydroxamic acids as novel, orally active matrix metalloproteinase inhibitors for the treatment of osteoarthritis.
Venkatesan Aranapakam, Jamie M Davis, George T Grosu, Jannie Baker, John Ellingboe, Vincent P Sandanayaka

J Med Chem· June 2003

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Spirocyclopropyl beta-lactams as mechanism-based inhibitors of serine beta-lactamases. Synthesis by rhodium-catalyzed cyclopropanation of 6-diazopenicillanate sulfone.
Vincent P Sandanayaka, Amar S Prashad, Youjun Yang, R Thomas Williamson, Yang I Lin

J Med Chem· June 2003

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Resistance to beta-lactam antibiotics: structure and mechanism based design of beta-lactamase inhibitors.
Vincent P Sandanayaka, Amar S Prashad

Curr Med Chem· June 2002

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