Publications by authors named "Louis Bedell"

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MMP-13 selective alpha-sulfone hydroxamates: identification of selective P1' amides.
Yvette M Fobian, John N Freskos, Thomas E Barta, Louis J Bedell, Robert Heintz

Bioorg Med Chem Lett· May 2011

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MMP-13 selective α-sulfone hydroxamates: a survey of P1' heterocyclic amide isosteres.
Thomas E Barta, Daniel P Becker, Louis J Bedell, Alan M Easton, Susan L Hockerman

Bioorg Med Chem Lett· May 2011

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Orally active MMP-1 sparing α-tetrahydropyranyl and α-piperidinyl sulfone matrix metalloproteinase (MMP) inhibitors with efficacy in cancer, arthritis, and cardiovascular disease.
Daniel P Becker, Thomas E Barta, Louis J Bedell, Terri L Boehm, Brian R Bond

J Med Chem· September 2010

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Discovery of novel leukotriene A4 hydrolase inhibitors based on piperidine and piperazine scaffolds.
Vincent Sandanayaka, Bjorn Mamat, Nikhil Bhagat, Louis Bedell, Gudrun Halldorsdottir

Bioorg Med Chem Lett· May 2010

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Synthesis and biological evaluation of novel 2,4-diaminoquinazoline derivatives as SMN2 promoter activators for the potential treatment of spinal muscular atrophy.
John Thurmond, Matthew E R Butchbach, Marty Palomo, Brian Pease, Munagala Rao, Louis Bedell

J Med Chem· February 2008

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Synthesis and structure-activity relationships of beta- and alpha-piperidine sulfone hydroxamic acid matrix metalloproteinase inhibitors with oral antitumor efficacy.
Daniel P Becker, Clara I Villamil, Thomas E Barta, Louis J Bedell, Terri L Boehm

J Med Chem· October 2005

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