Publications by authors named "Wade Clapp"

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Depletion of Fibrinogen Suppresses Growth of Primary Tumors and Metastasis of Pancreatic Ductal Adenocarcinoma.
Nayela N Chowdhury, Dana K Mitchell, Kadri Kangro, Kierra Eldridge, Sara Abrahams, D Wade Clapp

Gastroenterology· December 2025

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Focused ultrasound-mediated drug delivery of bevacizumab in treating NF2-related schwannomatosis in an animal model.
Jennifer L Spiegel, Alessandro De Maio, Manita V Patel, Omer J Ungar, Carolyn Lai, D Wade Clapp

Sci Rep· December 2025

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Recombinant Human Neuregulin1-β1 Significantly Reduces Schwannoma Growth in Mice.
Julia P Bischoff, Alexander Schulz, Christian Hagel, Robert Büttner, Michael Reuter, D Wade Clapp

Ann Neurol· October 2025

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Effect of bevacizumab on non-target intracranial meningiomas and non-vestibular schwannomas in NF2-related schwannomatosis: NF104.
Vihang Nakhate, Ina Ly, Alona Muzikansky, Otto Rapalino, Jeffrey C Allen, D Wade Clapp

J Neurooncol· July 2025

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A haploinsufficiency restoration strategy corrects neurobehavioral deficits in Nf1+/- mice.
Su Jung Park, Jodi L Lukkes, Ka-Kui Chan, Hayley P Drozd, Callie B Burgin, D Wade Clapp

J Clin Invest· July 2025

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TGFβ-dependent signaling drives tumor growth and aberrant extracellular matrix dynamics in NF1-associated plexiform neurofibroma.
Mohannad Abu-Sultanah, Zhuan Zhou, Chunhui Jiang, Dana K Mitchell, Waylan K Bessler, D Wade Clapp

Sci Adv· June 2025

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The RXR Agonist MSU-42011 Reduces Tumor Burden in a Murine Preclinical NF1-Deficient Model.
Pei-Yu Hung, Jessica A Moerland, Ana S Leal, Bilal Aleiwi, Edmund Ellsworth, D Wade Clapp

Cancers (Basel)· June 2025

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An induced pluripotent stem cell model of Schwann cell differentiation reveals NF2- related gene regulatory networks.
Olivia Lazaro, Sihong Li, William Carter, Jake Smiley, Oluwamayowa Awosika, D Wade Clapp

Res Sq· June 2025

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DLK1 Distinguishes Subsets of NF1-Associated Malignant Peripheral Nerve Sheath Tumors with Divergent Molecular Signatures.
Dana K Mitchell, Kylee Brewster, Stavriani C Makri, Jaffar Khan, Eric A Albright, Wade Clapp

Clin Cancer Res· May 2025

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Selumetinib in adults with NF1 and inoperable plexiform neurofibroma: a phase 2 trial.
Andrea M Gross, Geraldine O'Sullivan Coyne, Eva Dombi, Cecilia Tibery, William G Herrick, D Wade Clapp

Nat Med· January 2025

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Hydroxychloroquine prevents resistance and potentiates the antitumor effect of SHP2 inhibition in NF1-associated malignant peripheral nerve sheath tumors.
Sameer Farouk Sait, Kwan Ho Tang, Steven P Angus, Rebecca Brown, Daochun Sun, D Wade Clapp

Proc Natl Acad Sci U S A· January 2025

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Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK.
Long-Sheng Chang, Janet L Oblinger, Abbi E Smith, Marc Ferrer, Steven P Angus, D Wade Clapp

PLoS One· July 2024

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A novel induced pluripotent stem cell model of Schwann cell differentiation reveals - related gene regulatory networks of the extracellular matrix.
Olivia Lazaro, Sihong Li, William Carter, Oluwamayowa Awosika, Sylvia Robertson, Wade D Clapp

bioRxiv· July 2024

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Correction: Combined CDK4/6 and ERK1/2 Inhibition Enhances Antitumor Activity in NF1-Associated Plexiform Neurofibroma.
Alyssa C Flint, Dana K Mitchell, Steven P Angus, Abbi E Smith, Waylan Bessler, D Wade Clapp

Clin Cancer Res· May 2024

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Spatial Gene-Expression Profiling Unveils Immuno-oncogenic Programs of NF1-Associated Peripheral Nerve Sheath Tumor Progression.
Dana K Mitchell, Breanne Burgess, Emily E White, Abbi E Smith, Elizabeth A Sierra Potchanant, D Wade Clapp

Clin Cancer Res· March 2024

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New Ref-1/APE1 targeted inhibitors demonstrating improved potency for clinical applications in multiple cancer types.
Silpa Gampala, Hye-Ran Moon, Randall Wireman, Jacqueline Peil, Sonia Kiran, D Wade Clapp

Pharmacol Res· March 2024

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A Flattening of the Curve: The Challenge of Disparate Growth Rates in the Pediatric Subspecialties.
Robert J Vinci, D Wade Clapp, Ann Reed, Laura Degnon

J Pediatr· October 2023

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Combined CDK4/6 and ERK1/2 Inhibition Enhances Antitumor Activity in NF1-Associated Plexiform Neurofibroma.
Alyssa C Flint, Dana K Mitchell, Steven P Angus, Abbi E Smith, Waylan Bessler, D Wade Clapp

Clin Cancer Res· September 2023

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Multicenter, prospective, phase II study of maintenance bevacizumab for children and adults with NF2-related schwannomatosis and progressive vestibular schwannoma.
Scott R Plotkin, Jeffrey Allen, Girish Dhall, Jian L Campian, D Wade Clapp

Neuro Oncol· August 2023

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Correction: Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours.
Silpa Gampala, Fenil Shah, Chi Zhang, Steven D Rhodes, Olivia Babb, D Wade Clapp

Br J Cancer· October 2022

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SIK2 kinase synthetic lethality is driven by spindle assembly defects in FANCA-deficient cells.
Ka-Kui Chan, Zahi Abdul-Sater, Aditya Sheth, Dana K Mitchell, Richa Sharma, D Wade Clapp

Mol Oncol· February 2022

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Mitotic Errors Promote Genomic Instability and Leukemia in a Novel Mouse Model of Fanconi Anemia.
Donna M Edwards, Dana K Mitchell, Zahi Abdul-Sater, Ka-Kui Chan, Zejin Sun, D Wade Clapp

Front Oncol· November 2021

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PAK1 inhibition reduces tumor size and extends the lifespan of mice in a genetically engineered mouse model of Neurofibromatosis Type 2 (NF2).
Eric Hawley, Jeffrey Gehlhausen, Sofiia Karchugina, Hoi-Yee Chow, Daniela Araiza-Olivera, D Wade Clapp

Hum Mol Genet· August 2021

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Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours.
Silpa Gampala, Fenil Shah, Chi Zhang, Steven D Rhodes, Olivia Babb, D Wade Clapp

Br J Cancer· April 2021

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Irradiation of mutant mouse models of spinal plexiform neurofibromas drives pathologic progression and decreases survival.
Danny Laurent, Abbi E Smith, Waylan K Bessler, Marc Mendonca, Helen Chin-Sinex, D Wade Clapp

Neurooncol Adv· April 2021

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