Publications by authors named "Wai-Heng Lua"

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Variable-heavy (VH) families influencing IgA1&2 engagement to the antigen, FcαRI and superantigen proteins G, A, and L.
Wei-Li Ling, Chinh Tran-To Su, Wai-Heng Lua, Joshua Yi Yeo, Jun-Jie Poh

Sci Rep· April 2022

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Molecular Insights of Nickel Binding to Therapeutic Antibodies as a Possible New Antibody Superantigen.
Chinh Tran-To Su, Wai-Heng Lua, Jun-Jie Poh, Wei-Li Ling, Joshua Yi Yeo

Front Immunol· October 2021

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Essentially Leading Antibody Production: An Investigation of Amino Acids, Myeloma, and Natural V-Region Signal Peptides in Producing Pertuzumab and Trastuzumab Variants.
Wei-Li Ling, Chinh Tran-To Su, Wai-Heng Lua, Jun-Jie Poh, Yuen-Ling Ng

Front Immunol· June 2021

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Sagacity in antibody humanization for therapeutics, diagnostics and research purposes: considerations of antibody elements and their roles.
Wei-Li Ling, Wai-Heng Lua, Samuel Ken-En Gan

Antib Ther· April 2020

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Role of FcαR EC2 region in extracellular membrane localization.
Ser-Xian Phua, Wai-Heng Lua, Samuel Ken-En Gan

Cell Cycle· September 2019

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Role of the IgE variable heavy chain in FcεRIα and superantigen binding in allergy and immunotherapy.
Wai-Heng Lua, Chinh Tran-To Su, Joshua Yi Yeo, Jun-Jie Poh, Wei-Li Ling

J Allergy Clin Immunol· August 2019

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Effect of VH-VL Families in Pertuzumab and Trastuzumab Recombinant Production, Her2 and FcγIIA Binding.
Wei-Li Ling, Wai-Heng Lua, Jun-Jie Poh, Joshua Yi Yeo, David Philip Lane

Front Immunol· June 2019

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Author Correction: The effects of Antibody Engineering CH and CL in Trastuzumab and Pertuzumab recombinant models: Impact on antibody production and antigen-binding.
Wai-Heng Lua, Wei-Li Ling, Joshua Yi Yeo, Jun-Jie Poh, David Philip Lane

Sci Rep· July 2018

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Allosteric Effects between the Antibody Constant and Variable Regions: A Study of IgA Fc Mutations on Antigen Binding.
Chinh Tran-To Su, Wai-Heng Lua, Wei-Li Ling, Samuel Ken-En Gan

Antibodies (Basel)· June 2018

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The effects of Antibody Engineering CH and CL in Trastuzumab and Pertuzumab recombinant models: Impact on antibody production and antigen-binding.
Wai-Heng Lua, Wei-Li Ling, Joshua Yi Yeo, Jun-Jie Poh, David Philip Lane

Sci Rep· January 2018

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The role of Antibody Vκ Framework 3 region towards Antigen binding: Effects on recombinant production and Protein L binding.
Chinh Tran-To Su, Wei-Li Ling, Wai-Heng Lua, Jun-Jie Poh, Samuel Ken-En Gan

Sci Rep· June 2017

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Discovery of a novel splice variant of Fcar (CD89) unravels sequence segments necessary for efficient secretion: A story of bad signal peptides and good ones that nevertheless do not make it.
Wai-Heng Lua, Wei-Li Ling, Chinh Tran-To Su, Joshua Yi Yeo, Chandra Shekhar Verma

Cell Cycle· March 2017

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Structural analyses of 2015-updated drug-resistant mutations in HIV-1 protease: an implication of protease inhibitor cross-resistance.
Chinh Tran-To Su, Wei-Li Ling, Wai-Heng Lua, Yu-Xuan Haw, Samuel Ken-En Gan

BMC Bioinformatics· December 2016

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A search for synergy in the binding kinetics of Trastuzumab and Pertuzumab whole and F(ab) to Her2.
Wai-Heng Lua, Samuel Ken-En Gan, David Philip Lane, Chandra Shekhar Verma

NPJ Breast Cancer· August 2015

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Fast reversible single-step method for enhanced band contrast of polyacrylamide gels for automated detection.
Wei-Li Ling, Wai-Heng Lua, Samuel Ken-En Gan

Electrophoresis· May 2015

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Nuclear import of a lipid-modified transcription factor: mobilization of NFAT5 isoform a by osmotic stress.
Birgit Eisenhaber, Michaela Sammer, Wai Heng Lua, Wolfgang Benetka, Lai Ling Liew

Cell Cycle· November 2011

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