Publications by authors named "Walid A Houry"

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Small molecule dysregulation of ClpP activity via bidirectional allosteric pathways.
Marim M Barghash, Mark F Mabanglo, Samuel E Hoff, Dmytro Brozdnychenko, Keith S Wong, Walid A Houry

Structure· October 2025

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Aedes aegypti encodes an ATPase-active RUVBL1/2 complex.
Natália G Quel, Leonardo T Rosa, Larissa M Antonio, Glaucia M S Pinheiro, Leandro R S Barbosa, Walid A Houry

Int J Biol Macromol· July 2025

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Human protein interaction networks of ancestral and variant SARS-CoV-2 in organ-specific cells and bodily fluids.
Kirsten Broderick, Mohamed Taha Moutaoufik, Tatiana Saccon, Ramy Malty, Shahreen Amin, Walid A Houry

Nat Commun· July 2025

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Highly specific Immunoproteasome inhibitor M3258 induces proteotoxic stress and apoptosis in KMT2A::AFF1 driven acute lymphoblastic leukemia.
Tyler W Jenkins, Jacquelyn Elise Fitzgerald, Jieun Park, Addison M Wilson, Kristy L Berry, Walid A Houry

Sci Rep· May 2025

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Human papilloma virus (HPV) mediated cancers: an insightful update.
Sadaf Khursheed Baba, Shahad Shahdad Eissa Alblooshi, Reem Yaqoob, Shalini Behl, Mansour Al Saleem, Walid A Houry

J Transl Med· April 2025

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Tuning TCR complex recruitment to the T cell antigen coupler (TAC) enhances TAC-T cell function.
Trevor M Morey, Tania Benatar, Stacey X Xu, Ling Wang, Philbert Ip, Walid A Houry

Sci Rep· February 2025

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Targeting protein homeostasis with small molecules as a strategy for the development of pan-coronavirus antiviral therapies.
Yu-Qian Mao, Shahrzad Jahanshahi, Ramy Malty, David A J Van Ommen, Yimei Wan, Walid A Houry

Commun Biol· November 2024

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Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for Antibiotics that Dysregulate Bacterial ClpP Proteases.
Funing Lin, Mark F Mabanglo, Jin Lin Zhou, Gursonika Binepal, Marim M Barghash, Walid A Houry

J Med Chem· September 2024

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Target-locked: A mechanism for disaggregase binding to aggregated proteins.
Trevor M Morey, Walid A Houry

J Biol Chem· April 2024

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DPCD is a regulator of R2TP in ciliogenesis initiation through Akt signaling.
Yu-Qian Mao, Thiago V Seraphim, Yimei Wan, Ruikai Wu, Etienne Coyaud, Walid A Houry

Cell Rep· February 2024

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Second international symposium on the chaperone code, 2023.
Johannes Buchner, Milad J Alasady, Sarah J Backe, Brian S J Blagg, Richard L Carpenter, Walid A Houry

Cell Stress Chaperones· February 2024

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Broad spectrum post-entry inhibitors of coronavirus replication: Cardiotonic steroids and monensin.
Shahrzad Jahanshahi, Hong Ouyang, Choudhary Ahmed, Ali Zahedi Amiri, Subha Dahal, Walid A Houry

Virology· January 2024

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The RavA-ViaA chaperone complex modulates bacterial persistence through its association with the fumarate reductase enzyme.
Vaibhav Bhandari, Sean E Reichheld, Scott Houliston, Alexander Lemak, Cheryl H Arrowsmith, Walid A Houry

J Biol Chem· October 2023

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On a path toward a broad-spectrum anti-viral: inhibition of HIV-1 and coronavirus replication by SR kinase inhibitor harmine.
Subha Dahal, Kiera Clayton, Tyler Cabral, Ran Cheng, Shahrzad Jahanshahi, Walid A Houry

J Virol· October 2023

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Unveiling the Role of Sorghum RPAP3 in the Function of R2TP Complex: Insights into Protein Assembly in Plants.
Larissa Machado Antonio, Gustavo Henrique Martins, Annelize Zambon Barbosa Aragão, Natália Galdi Quel, Gabriel Zazeri, Walid A Houry

Plants (Basel)· August 2023

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Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome.
Mark F Mabanglo, Keith S Wong, Marim M Barghash, Elisa Leung, Stephanie H W Chuang, Walid A Houry

Structure· February 2023

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Cellular functions of the ClpP protease impacting bacterial virulence.
Mazen E Aljghami, Marim M Barghash, Emily Majaesic, Vaibhav Bhandari, Walid A Houry

Front Mol Biosci· December 2022

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Characterization of TR-107, a novel chemical activator of the human mitochondrial protease ClpP.
Emily M J Fennell, Lucas J Aponte-Collazo, Joshua D Wynn, Kristina Drizyte-Miller, Elisa Leung, Walid A Houry

Pharmacol Res Perspect· August 2022

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Analysis of the Evolution of the MoxR ATPases.
Vaibhav Bhandari, David A J Van Ommen, Keith S Wong, Walid A Houry

J Phys Chem A· July 2022

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The Role of Hsp90-R2TP in Macromolecular Complex Assembly and Stabilization.
Jeffrey Lynham, Walid A Houry

Biomolecules· July 2022

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Recent structural insights into the mechanism of ClpP protease regulation by AAA+ chaperones and small molecules.
Mark F Mabanglo, Walid A Houry

J Biol Chem· May 2022

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Substrates and interactors of the ClpP protease in the mitochondria.
Mark F Mabanglo, Vaibhav Bhandari, Walid A Houry

Curr Opin Chem Biol· February 2022

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Assembly principles of the human R2TP chaperone complex reveal the presence of R2T and R2P complexes.
Thiago V Seraphim, Nardin Nano, Yiu Wing Sunny Cheung, Siripat Aluksanasuwan, Carolina Colleti, Walid A Houry

Structure· January 2022

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The Thiazole-5-Carboxamide GPS491 Inhibits HIV-1, Adenovirus, and Coronavirus Replication by Altering RNA Processing/Accumulation.
Subha Dahal, Ran Cheng, Peter K Cheung, Terek Been, Ramy Malty, Walid A Houry

Viruses· December 2021

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Author Correction: Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex.
Kamran Rizzolo, Angela Yeou Hsiung Yu, Adedeji Ologbenla, Sa Rang Kim, Haojie Zhu, Walid A Houry

Nat Commun· May 2021

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