Publications by authors named "Walter Ferlin"

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NI-3201 Is a Bispecific Antibody Mediating PD-L1-Dependent CD28 Co-stimulation on T Cells for Enhanced Tumor Control.
Sara Majocchi, Pauline Lloveras, Lise Nouveau, Margaux Legrand, Alizee Viandier, Walter G Ferlin

Cancer Immunol Res· March 2025

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Selective activation of interleukin-2/interleukin-15 receptor signaling in tumor microenvironment using paired bispecific antibodies.
Julien Montorfani, Eric Hatterer, Laurence Chatel, Adeline Lesnier, Alizée Viandier, Walter Ferlin

J Immunother Cancer· March 2025

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Persistently active interferon-γ pathway and expansion of T-bet B cells in a subset of patients with childhood-onset systemic lupus erythematosus.
Gian Marco Moneta, Claudia Bracaglia, Ivan Caiello, Chiara Farroni, Denise Pires Marafon, Walter Ferlin

Eur J Immunol· July 2023

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CD47xCD19 bispecific antibody triggers recruitment and activation of innate immune effector cells in a B-cell lymphoma xenograft model.
Xavier Chauchet, Laura Cons, Laurence Chatel, Bruno Daubeuf, Gérard Didelot, Walter Ferlin

Exp Hematol Oncol· May 2022

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Immunological analysis of the murine anti-CD3-induced cytokine release syndrome model and therapeutic efficacy of anti-cytokine antibodies.
Lise Nouveau, Vanessa Buatois, Laura Cons, Laurence Chatel, Guillemette Pontini, Walter G Ferlin

Eur J Immunol· August 2021

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Selective CD47 targeting with a bispecific antibody.
Walter Ferlin, Krzysztof Masternak, Limin Shang

Cancer Immunol Immunother· April 2021

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Role of interferon-γ in immune-mediated graft failure after allogeneic hematopoietic stem cell transplantation.
Pietro Merli, Ignazio Caruana, Rita De Vito, Luisa Strocchio, Gerrit Weber, Walter Ferlin

Haematologica· November 2019

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Co-engaging CD47 and CD19 with a bispecific antibody abrogates B-cell receptor/CD19 association leading to impaired B-cell proliferation.
Eric Hatterer, Leticia Barba, Nelly Noraz, Bruno Daubeuf, Jean-Pierre Aubry-Lachainaye, Walter Ferlin

MAbs· July 2019

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ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer.
Mohamed I Saad, Sultan Alhayyani, Louise McLeod, Liang Yu, Mohammad Alanazi, Walter Ferlin

EMBO Mol Med· April 2019

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Preclinical Development of a Bispecific Antibody that Safely and Effectively Targets CD19 and CD47 for the Treatment of B-Cell Lymphoma and Leukemia.
Vanessa Buatois, Zoë Johnson, Susana Salgado-Pires, Anne Papaioannou, Eric Hatterer, Walter G Ferlin

Mol Cancer Ther· August 2018

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IL-6 trans-signalling mediates trabecular, but not cortical, bone loss after ovariectomy.
Leah Lazzaro, Brett A Tonkin, Ingrid J Poulton, Narelle E McGregor, Walter Ferlin

Bone· July 2018

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NI-0801, an anti-chemokine (C-X-C motif) ligand 10 antibody, in patients with primary biliary cholangitis and an incomplete response to ursodeoxycholic acid.
Kathy L de Graaf, Geneviève Lapeyre, Florence Guilhot, Walter Ferlin, Stuart M Curbishley

Hepatol Commun· May 2018

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Neutralization of IFN-γ reverts clinical and laboratory features in a mouse model of macrophage activation syndrome.
Giusi Prencipe, Ivan Caiello, Antonia Pascarella, Alexei A Grom, Claudia Bracaglia, Walter G Ferlin

J Allergy Clin Immunol· April 2018

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Tumor-Directed Blockade of CD47 with Bispecific Antibodies Induces Adaptive Antitumor Immunity.
Elie Dheilly, Stefano Majocchi, Valéry Moine, Gérard Didelot, Lucile Broyer, Walter G Ferlin

Antibodies (Basel)· January 2018

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The antiviral restriction factor IFN-induced transmembrane protein 3 prevents cytokine-driven CMV pathogenesis.
Maria A Stacey, Simon Clare, Mathew Clement, Morgan Marsden, Juneid Abdul-Karim, Walter Ferlin

J Clin Invest· April 2017

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Epstein-Barr virus-induced gene 3 (EBI3) can mediate IL-6 -signaling.
Salma Chehboun, Jérémie Labrecque-Carbonneau, Sarah Pasquin, Yasmine Meliani, Bouchra Meddah, Walter Ferlin

J Biol Chem· April 2017

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Evaluation of Multiple Immunoassay Technology Platforms to Select the Anti-Drug Antibody Assay Exhibiting the Most Appropriate Drug and Target Tolerance.
Justine Collet-Brose, Pierre-Jean Couble, Maureen R Deehan, Robert J Nelson, Walter G Ferlin

J Immunol Res· March 2017

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Antibody Neutralization of CXCL10 Is Dependent on Binding to Free and Not Endothelial-bound Chemokine: IMPLICATIONS FOR THE DESIGN OF A NEW GENERATION OF ANTI-CHEMOKINE THERAPEUTIC ANTIBODIES.
Pauline Bonvin, Franck Gueneau, Vanessa Buatois, Maud Charreton-Galby, Stanley Lasch, Walter Ferlin

J Biol Chem· March 2017

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Use of a mouse model to identify a blood biomarker for IFNγ activity in pediatric secondary hemophagocytic lymphohistiocytosis.
Vanessa Buatois, Laurence Chatel, Laura Cons, Sabrina Lory, Françoise Richard, Walter G Ferlin

Transl Res· February 2017

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Selective Blockade of the Ubiquitous Checkpoint Receptor CD47 Is Enabled by Dual-Targeting Bispecific Antibodies.
Elie Dheilly, Valéry Moine, Lucile Broyer, Susana Salgado-Pires, Zoë Johnson, Walter Ferlin

Mol Ther· February 2017

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Elevated circulating levels of interferon-γ and interferon-γ-induced chemokines characterise patients with macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.
Claudia Bracaglia, Kathy de Graaf, Denise Pires Marafon, Florence Guilhot, Walter Ferlin

Ann Rheum Dis· January 2017

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Spatiotemporal expression of endogenous TLR4 ligands leads to inflammation and bone erosion in mouse collagen-induced arthritis.
Gaëlle Wambiekele Kiyeko, Eric Hatterer, Suzanne Herren, Irene Di Ceglie, Peter L van Lent, Walter Ferlin

Eur J Immunol· November 2016

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A specific anti-citrullinated protein antibody profile identifies a group of rheumatoid arthritis patients with a toll-like receptor 4-mediated disease.
Eric Hatterer, Limin Shang, Pierre Simonet, Suzanne Herren, Bruno Daubeuf, Walter Ferlin

Arthritis Res Ther· October 2016

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Blocking interferon γ reduces expression of chemokines CXCL9, CXCL10 and CXCL11 and decreases macrophage infiltration in ex vivo cultured arteries from patients with giant cell arteritis.
Marc Corbera-Bellalta, Ester Planas-Rigol, Ester Lozano, Nekane Terrades-García, Marco A Alba, Walter G Ferlin

Ann Rheum Dis· June 2016

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IL6 Trans-signaling Promotes KRAS-Driven Lung Carcinogenesis.
Gavin D Brooks, Louise McLeod, Sultan Alhayyani, Alistair Miller, Prudence A Russell, Walter Ferlin

Cancer Res· February 2016

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