Publications by authors named "Walter Sebald"

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Lessons on protein structure from interleukin-4: All disulfides are not created equal.
Daniela C Vaz, J Rui Rodrigues, Nuno Loureiro-Ferreira, Thomas D Müller, Walter Sebald

Proteins· February 2024

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The BMP-2 mutant L51P: a BMP receptor IA binding-deficient inhibitor of noggin.
Hany Mohamed Khattab, Satoshi Kubota, Masaharu Takigawa, Takuo Kuboki, Walter Sebald

J Bone Miner Metab· March 2019

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Utilizing BMP-2 muteins for treatment of multiple myeloma.
Axel Seher, Charlotte Lagler, Thorsten Stühmer, Urs Dietmar Achim Müller-Richter, Alexander Christian Kübler, Walter Sebald

PLoS One· September 2017

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Bone Recuperation After rhBMP-2 Insertion in Alcoholic Animals-Experimental Study.
Bruna G dos S Kotake, Leda M P Salzedas, Edilson Ervolino, Ricardo A J Calzzani, Walter Sebald

Curr Pharm Des· May 2016

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GDF-5 can act as a context-dependent BMP-2 antagonist.
Uwe Klammert, Thomas D Mueller, Tina V Hellmann, Kristian K Wuerzler, Alexander Kotzsch, Walter Sebald

BMC Biol· September 2015

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Regeneration of calvarial defects with Escherichia coli -derived rhBMP-2 adsorbed in PLGA membrane.
Mitsuaki Ono, Wataru Sonoyama, Kazuki Nema, Emilio Satoshi Hara, Yasutaka Oida, Walter Sebald

Cells Tissues Organs· January 2015

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The BMP2 antagonist inhibitor L51P enhances the osteogenic potential of BMP2 by simultaneous and delayed synergism.
Hany Mohamed Khattab, Mitsuaki Ono, Wataru Sonoyama, Yasutaka Oida, Shigehiko Shinkawa, Walter Sebald

Bone· December 2014

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IL-4 analogues with site-specific chemical modification at position 121 inhibit IL-4 and IL-13 biological activities.
Viswanadham Duppatla, Maja Gjorgjevikj, Werner Schmitz, Heike M Hermanns, Carmen M Schäfer, Walter Sebald

Bioconjug Chem· January 2014

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The clip-segment of the von Willebrand domain 1 of the BMP modulator protein Crossveinless 2 is preformed.
Juliane E Fiebig, Stella E Weidauer, Li-Yan Qiu, Markus Bauer, Peter Schmieder, Walter Sebald

Molecules· September 2013

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Regarding the mechanism of action of a proposed peptide agonist of the bone morphogenetic protein receptor activin-like kinase 3.
Malcolm Whitman, Vicki Rosen, Ali H Brivanlou, Jay C Groppe, Walter Sebald

Nat Med· July 2013

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Biological evaluation of the bone healing process after application of two potentially osteogenic proteins: an animal experimental model.
João P M Issa, Helton L A Defino, Walter Sebald, Joaquim Coutinho-Netto, Mamie M Iyomasa

Gerodontology· December 2012

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Inhibition of endogenous antagonists with an engineered BMP-2 variant increases BMP-2 efficacy in rat femoral defect healing.
Hans-Jörg Sebald, Frank M Klenke, Mark Siegrist, Christoph E Albers, Walter Sebald

Acta Biomater· October 2012

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L51P - A BMP2 variant with osteoinductive activity via inhibition of Noggin.
Christoph E Albers, Wilhelm Hofstetter, Hans-Jörg Sebald, Walter Sebald, Klaus A Siebenrock

Bone· September 2012

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Enzymatic deglutathionylation to generate interleukin-4 cysteine muteins with free thiol.
Viswanadham Duppatla, Maja Gjorgjevikj, Werner Schmitz, Mathias Kottmair, Thomas D Mueller, Walter Sebald

Bioconjug Chem· July 2012

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Influence of low-level laser associated with osteogenic proteins recombinant human BMP-2 and Hevea brasiliensis on bone repair in Wistar rats.
Mamie Mizusaki Iyomasa, João Paulo Mardegan Issa, Mirella Lemos de Queiróz Tavares, Yamba Carla Lara Pereira, Maria Bernadete Sasso Stuani, Walter Sebald

Microsc Res Tech· February 2012

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Bone repair investigation using rhBMP-2 and angiogenic protein extracted from latex.
João Paulo Mardegan Issa, Helton Luiz Aparecido Defino, Yamba Carla Lara Pereira, Joaquim Coutinho Netto, Walter Sebald

Microsc Res Tech· February 2012

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New insights into the molecular mechanism of multiple synostoses syndrome (SYNS): mutation within the GDF5 knuckle epitope causes noggin-resistance.
Gerburg K Schwaerzer, Christian Hiepen, Heinrich Schrewe, Joachim Nickel, Frank Ploeger, Walter Sebald

J Bone Miner Res· February 2012

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Structure analysis of the IL-5 ligand-receptor complex reveals a wrench-like architecture for IL-5Rα.
Edwin Patino, Alexander Kotzsch, Stefan Saremba, Joachim Nickel, Werner Schmitz, Walter Sebald

Structure· December 2011

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Application of low-level laser irradiation (LLLI) and rhBMP-2 in critical bone defect of ovariectomized rats: histomorphometric evaluation.
Selma Siéssere, Luiz Gustavo de Sousa, João Paulo Mardegan Issa, Mamie Mizusaki Iyomasa, Dimitrius Leonardo Pitol, Walter Sebald

Photomed Laser Surg· July 2011

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N-terminal specificity of PEGylation of human bone morphogenetic protein-2 at acidic pH.
Junli Hu, Walter Sebald

Int J Pharm· July 2011

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Purification, crystallization and preliminary data analysis of the ligand-receptor complex of the growth and differentiation factor 5 variant R57A (GDF5R57A) and BMP receptor IA (BRIA).
Joachim Nickel, Alexander Kotzsch, Walter Sebald, Thomas D Mueller

Acta Crystallogr Sect F Struct Biol Cryst Commun· May 2011

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Gene expression profiling of connective tissue growth factor (CTGF) stimulated primary human tenon fibroblasts reveals an inflammatory and wound healing response in vitro.
Axel Seher, Joachim Nickel, Thomas D Mueller, Susanne Kneitz, Susanne Gebhardt, Walter Sebald

Mol Vis· January 2011

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Site-specific PEGylation of bone morphogenetic protein-2 cysteine analogues.
Junli Hu, Viswanadham Duppatla, Stefan Harth, Werner Schmitz, Walter Sebald

Bioconjug Chem· October 2010

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Binding between Crossveinless-2 and Chordin von Willebrand factor type C domains promotes BMP signaling by blocking Chordin activity.
Jin-Li Zhang, Lucy J Patterson, Li-Yan Qiu, Daria Graziussi, Walter Sebald

PLoS One· September 2010

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A selection fit mechanism in BMP receptor IA as a possible source for BMP ligand-receptor promiscuity.
Stefan Harth, Alexander Kotzsch, Junli Hu, Walter Sebald, Thomas D Mueller

PLoS One· September 2010

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