Publications by authors named "Warwick S Nesbitt"

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Characterisation of hydrodynamic trapping in microfluidic cross-slot devices for high strain rate applications.
Aravind George, Farzan Akbaridoust, Nurul A Zainal Abidin, Warwick S Nesbitt, Ivan Marusic

Lab Chip· June 2023

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A microfluidic method to investigate platelet mechanotransduction under extensional strain.
Nurul A Zainal Abidin, Mariia Timofeeva, Crispin Szydzik, Farzan Akbaridoust, Chitrarth Lav, Warwick S Nesbitt

Res Pract Thromb Haemost· January 2023

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An extensional strain sensing mechanosome drives adhesion-independent platelet activation at supraphysiological hemodynamic gradients.
Nurul A Zainal Abidin, Eric K W Poon, Crispin Szydzik, Mariia Timofeeva, Farzan Akbaridoust, Warwick S Nesbitt

BMC Biol· March 2022

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A Review of Design Considerations for Hemocompatibility within Microfluidic Systems.
Crispin Szydzik, Rose J Brazilek, Warwick S Nesbitt

Semin Thromb Hemost· July 2020

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In vitro flow based systems to study platelet function and thrombus formation: Recommendations for standardization: Communication from the SSC on Biorheology of the ISTH.
Pierre H Mangin, Elizabeth E Gardiner, Warwick S Nesbitt, Steven W Kerrigan, Netanel Korin

J Thromb Haemost· March 2020

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Active Micropump-Mixer for Rapid Antiplatelet Drug Screening in Whole Blood.
Crispin Szydzik, Rose J Brazilek, Farzan Akbaridoust, Charitha de Silva, Mitchell Moon, Warwick S Nesbitt

Anal Chem· August 2019

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The mode of anesthesia influences outcome in mouse models of arterial thrombosis.
Maithili Sashindranath, Sharelle A Sturgeon, Shauna French, Daphne D D Craenmehr, Carly Selan, Warwick S Nesbitt

Res Pract Thromb Haemost· April 2019

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The PI 3-kinase PI3KC2α regulates mouse platelet membrane structure and function independently of membrane lipid composition.
Maria V Selvadurai, Rose J Brazilek, Mitchell J Moon, Jean-Yves Rinckel, Anita Eckly, Warwick S Nesbitt

FEBS Lett· January 2019

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Elastomeric microvalve geometry affects haemocompatibility.
Crispin Szydzik, Rose J Brazilek, Khashayar Khoshmanesh, Farzan Akbaridoust, Markus Knoerzer, Warwick S Nesbitt

Lab Chip· June 2018

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Application of a strain rate gradient microfluidic device to von Willebrand's disease screening.
Rose J Brazilek, Francisco J Tovar-Lopez, Angus K T Wong, Huyen Tran, Amanda S Davis, Warwick S Nesbitt

Lab Chip· July 2017

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Nonlinear Dynamic Modelling of Platelet Aggregation via Microfluidic Devices.
Miguel E Combariza, Xinghuo Yu, Warwick S Nesbitt, Arnan Mitchell, Francisco J Tovar-Lopez

IEEE Trans Biomed Eng· July 2015

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An investigation on platelet transport during thrombus formation at micro-scale stenosis.
Francisco Javier Tovar-Lopez, Gary Rosengarten, Mahyar Nasabi, Vijay Sivan, Khashayar Khoshmanesh, Warwick S Nesbitt

PLoS One· February 2015

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A multimode-TIRFM and microfluidic technique to examine platelet adhesion dynamics.
Warwick S Nesbitt, Francisco J Tovar-Lopez, Erik Westein, Ian S Harper, Shaun P Jackson

Methods Mol Biol· February 2014

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Dok-2 adaptor protein regulates the shear-dependent adhesive function of platelet integrin αIIbβ3 in mice.
Sascha C Hughan, Christopher M Spring, Simone M Schoenwaelder, Sharelle Sturgeon, Imala Alwis, Warwick S Nesbitt

J Biol Chem· February 2014

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A live cell micro-imaging technique to examine platelet calcium signaling dynamics under blood flow.
Warwick S Nesbitt, Ian S Harper, Simone M Schoenwaelder, Yuping Yuan, Shaun P Jackson

Methods Mol Biol· April 2012

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Structural and hydrodynamic simulation of an acute stenosis-dependent thrombosis model in mice.
Francisco J Tovar-Lopez, Gary Rosengarten, Khashayar Khoshmanesh, Erik Westein, Shaun P Jackson, Warwick S Nesbitt

J Biomech· April 2011

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A microfluidics device to monitor platelet aggregation dynamics in response to strain rate micro-gradients in flowing blood.
Francisco Javier Tovar-Lopez, Gary Rosengarten, Erik Westein, Khashayar Khoshmanesh, Shaun P Jackson, Warwick S Nesbitt

Lab Chip· February 2010

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Phosphoinositide 3-kinase p110 beta regulates integrin alpha IIb beta 3 avidity and the cellular transmission of contractile forces.
Simone M Schoenwaelder, Akiko Ono, Warwick S Nesbitt, Joanna Lim, Kate Jarman

J Biol Chem· January 2010

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A shear gradient-dependent platelet aggregation mechanism drives thrombus formation.
Warwick S Nesbitt, Erik Westein, Francisco Javier Tovar-Lopez, Elham Tolouei, Arnan Mitchell

Nat Med· June 2009

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Identification of a fibrin-independent platelet contractile mechanism regulating primary hemostasis and thrombus growth.
Akiko Ono, Erik Westein, Sarah Hsiao, Warwick S Nesbitt, Justin R Hamilton

Blood· July 2008

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Imaging signaling processes in platelets.
Warwick S Nesbitt, Shaun P Jackson

Blood Cells Mol Dis· September 2007

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Identification of a 2-stage platelet aggregation process mediating shear-dependent thrombus formation.
Mhairi J Maxwell, Erik Westein, Warwick S Nesbitt, Simon Giuliano, Sacha M Dopheide

Blood· January 2007

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The impact of blood rheology on the molecular and cellular events underlying arterial thrombosis.
Warwick S Nesbitt, Pierre Mangin, Hatem H Salem, Shaun P Jackson

J Mol Med (Berl)· December 2006

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PI 3-kinase p110beta: a new target for antithrombotic therapy.
Shaun P Jackson, Simone M Schoenwaelder, Isaac Goncalves, Warwick S Nesbitt, Cindy L Yap

Nat Med· May 2005

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