Publications by authors named "Wendell Lim"

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Engineering Inducible Cell Fate Transitions by Harnessing Epigenetic Silencing.
Oscar A Campos, Alessandro Migliara, Satoshi Toda, Pilar Lopez, Wendell A Lim

bioRxiv· September 2025

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Programmable microparticles rewire CAR signaling to enable super-physiological expansion of human T cells .
Qinghe Zeng, Landon Flemming, Yuanzhou Chen, Thomas Mazumder, Heinz Hammerlindl, Wendell A Lim

bioRxiv· July 2025

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Engineered SH3-Derived Sherpabodies Function as a Modular Platform for Targeted T-cell Immunotherapy.
Rogelio A Hernández-López, Tapio Kesti, Anna R Mäkelä, Zhe Zhao, Wei Yu, Wendell A Lim

Cancer Res· May 2025

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Synthetic organizer cells guide development via spatial and biochemical instructions.
Toshimichi Yamada, Coralie Trentesaux, Jonathan M Brunger, Yini Xiao, Adam J Stevens, Wendell A Lim

Cell· February 2025

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Programming tissue-sensing T cells that deliver therapies to the brain.
Milos S Simic, Payal B Watchmaker, Sasha Gupta, Yuan Wang, Sharon A Sagan, Wendell A Lim

Science· December 2024

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Engineering synthetic suppressor T cells that execute locally targeted immunoprotective programs.
Nishith R Reddy, Hasna Maachi, Yini Xiao, Milos S Simic, Wei Yu, Wendell A Lim

Science· December 2024

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-designed minibinders expand the synthetic biology sensing repertoire.
Zara Y Weinberg, Sarah S Soliman, Matthew S Kim, Devan H Shah, Irene P Chen, Wendell A Lim

bioRxiv· August 2024

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Degron-Based bioPROTACs for Controlling Signaling in CAR T Cells.
Matthew S Kim, Hersh K Bhargava, Gavin E Shavey, Wendell A Lim, Hana El-Samad

ACS Synth Biol· August 2024

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Degron-based bioPROTACs for controlling signaling in CAR T cells.
Matthew S Kim, Hersh K Bhargava, Gavin E Shavey, Wendell A Lim, Hana El-Samad

bioRxiv· February 2024

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General Characteristics and Design Taxonomy of Chatbots for COVID-19: Systematic Review.
Wendell Adrian Lim, Razel Custodio, Monica Sunga, Abegail Jayne Amoranto, Raymond Francis Sarmiento

J Med Internet Res· January 2024

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Golden age of immunoengineering.
Wilson W Wong, Wendell A Lim

Immunol Rev· November 2023

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An immune-based tool platform for in vivo cell clearance.
Jieqiong Zhang, Tatsuya Tsukui, Xiumin Wu, Alyssa Brito, John Maxwell Trumble, Wendell A Lim

Life Sci Alliance· August 2023

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Instructional materials that control cellular activity through synthetic Notch receptors.
Joanne C Lee, Hannah J Brien, Bonnie L Walton, Zachary M Eidman, Satoshi Toda, Wendell A Lim

Biomaterials· June 2023

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CAR-T Cell-Mediated B-Cell Depletion in Central Nervous System Autoimmunity.
Sasha Gupta, Milos Simic, Sharon A Sagan, Chanelle Shepherd, Jason Duecker, Wendell Lim

Neurol Neuroimmunol Neuroinflamm· March 2023

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Programming multicellular assembly with synthetic cell adhesion molecules.
Adam J Stevens, Andrew R Harris, Josiah Gerdts, Ki H Kim, Coralie Trentesaux, Wendell A Lim

Nature· February 2023

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Harnessing synthetic biology to engineer organoids and tissues.
Coralie Trentesaux, Toshimichi Yamada, Ophir D Klein, Wendell A Lim

Cell Stem Cell· January 2023

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Rethinking cancer targeting strategies in the era of smart cell therapeutics.
Greg M Allen, Wendell A Lim

Nat Rev Cancer· December 2022

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Decoding CAR T cell phenotype using combinatorial signaling motif libraries and machine learning.
Kyle G Daniels, Shangying Wang, Milos S Simic, Hersh K Bhargava, Sara Capponi, Wendell A Lim

Science· December 2022

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Synthetic cytokine circuits that drive T cells into immune-excluded tumors.
Greg M Allen, Nicholas W Frankel, Nishith R Reddy, Hersh K Bhargava, Maia A Yoshida, Wendell A Lim

Science· December 2022

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The emerging era of cell engineering: Harnessing the modularity of cells to program complex biological function.
Wendell A Lim

Science· November 2022

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SynNotch-CAR T cells overcome challenges of specificity, heterogeneity, and persistence in treating glioblastoma.
Joseph H Choe, Payal B Watchmaker, Milos S Simic, Ryan D Gilbert, Aileen W Li, Wendell A Lim

Sci Transl Med· April 2021

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T cells selectively filter oscillatory signals on the minutes timescale.
Geoff P O'Donoghue, Lukasz J Bugaj, Warren Anderson, Kyle G Daniels, David J Rawlings, Wendell A Lim

Proc Natl Acad Sci U S A· March 2021

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T cell circuits that sense antigen density with an ultrasensitive threshold.
Rogelio A Hernandez-Lopez, Wei Yu, Katelyn A Cabral, Olivia A Creasey, Maria Del Pilar Lopez Pazmino, Wendell A Lim

Science· March 2021

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DNA scaffolds enable efficient and tunable functionalization of biomaterials for immune cell modulation.
Xiao Huang, Jasper Z Williams, Ryan Chang, Zhongbo Li, Cassandra E Burnett, Wendell A Lim

Nat Nanotechnol· February 2021

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Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.
Lei S Qi, Matthew H Larson, Luke A Gilbert, Jennifer A Doudna, Jonathan S Weissman, Wendell A Lim

Cell· February 2021

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