Publications by authors named "Whitney England"

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Human microglia differentially respond to β-amyloid, tau, and combined Alzheimer's disease pathologies in vivo.
Morgan A Coburn, Ghazaleh Eskandari-Sedighi, Jonathan Hasselmann, Whitney England, Sepideh Kiani Shabestari

Alzheimers Dement· November 2025

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Novel photocrosslinking chemical probes utilized for high-resolution spatial transcriptomics.
Leslie Spitalny, Natalie Falco, Whitney England, Tyler Allred, Robert C Spitale

RSC Chem Biol· March 2025

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Aberrant splicing in Huntington's disease accompanies disrupted TDP-43 activity and altered m6A RNA modification.
Thai B Nguyen, Ricardo Miramontes, Carlos Chillon-Marinas, Roy Maimon, Sonia Vazquez-Sanchez, Whitney E England

Nat Neurosci· February 2025

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The anticancer compound JTE-607 reveals hidden sequence specificity of the mRNA 3' processing machinery.
Liang Liu, Angela M Yu, Xiuye Wang, Lindsey V Soles, Xueyi Teng, Whitney England

Nat Struct Mol Biol· December 2023

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Potential for natural attenuation of crude oil hydrocarbons in benthic microbiomes near coastal communities in Kivalliq, Nunavut, Canada.
Meng Ji, Alastair F Smith, Jayne E Rattray, Whitney E England, Casey R J Hubert

Mar Pollut Bull· November 2023

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Aberrant splicing in Huntington's disease via disrupted TDP-43 activity accompanied by altered m6A RNA modification.
Thai B Nguyen, Ricardo Miramontes, Carlos Chillon-Marinas, Roy Maimon, Sonia Vazquez-Sanchez, Whitney E England

bioRxiv· November 2023

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Engineering an inhibitor-resistant human CSF1R variant for microglia replacement.
Jean Paul Chadarevian, Sonia I Lombroso, Graham C Peet, Jonathan Hasselmann, Christina Tu, Whitney England

J Exp Med· March 2023

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The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model.
Christel Claes, Whitney E England, Emma P Danhash, Sepideh Kiani Shabestari, Amit Jairaman

Alzheimers Dement· October 2022

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Tracking Emergence and Spread of SARS-CoV-2 Omicron Variant in Large and Small Communities by Wastewater Monitoring in Alberta, Canada.
Casey R J Hubert, Nicole Acosta, Barbara J M Waddell, Maria E Hasing, Yuanyuan Qiu, Whitney E England

Emerg Infect Dis· September 2022

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An atlas of posttranslational modifications on RNA binding proteins.
Whitney E England, Jingtian Wang, Siwei Chen, Pierre Baldi, Ryan A Flynn

Nucleic Acids Res· May 2022

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Exploiting Endogenous Enzymes for Cancer-Cell Selective Metabolic Labeling of RNA in Vivo.
Samantha Beasley, Abigail Vandewalle, Monika Singha, Kim Nguyen, Whitney England

J Am Chem Soc· April 2022

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Diverse functional elements in RNA predicted transcriptome-wide by orthogonal RNA structure probing.
Dalen Chan, Chao Feng, Whitney E England, Dana Wyman, Ryan A Flynn

Nucleic Acids Res· November 2021

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Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer's disease.
Christel Claes, Emma Pascal Danhash, Jonathan Hasselmann, Jean Paul Chadarevian, Sepideh Kiani Shabestari, Whitney E England

Mol Neurodegener· July 2021

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Huntington's disease mice and human brain tissue exhibit increased G3BP1 granules and TDP43 mislocalization.
Isabella I Sanchez, Thai B Nguyen, Whitney E England, Ryan G Lim, Anthony Q Vu

J Clin Invest· June 2021

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Chemical Approaches To Analyzing RNA Structure Transcriptome-Wide.
Whitney E England, Chely M Garfio, Robert C Spitale

Chembiochem· April 2021

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Allele-Specific RNA Knockdown with a Biologically Stable and Catalytically Efficient XNAzyme.
Kim Nguyen, Yajun Wang, Whitney E England, John C Chaput, Robert C Spitale

J Am Chem Soc· March 2021

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Identification of novel regulators of dendrite arborization using cell type-specific RNA metabolic labeling.
Mohamed Y Aboukilila, Josephine D Sami, Jingtian Wang, Whitney England, Robert C Spitale

PLoS One· January 2021

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Structural disruption of exonic stem-loops immediately upstream of the intron regulates mammalian splicing.
Kaushik Saha, Whitney England, Mike Minh Fernandez, Tapan Biswas, Robert C Spitale

Nucleic Acids Res· June 2020

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An optimized chemical-genetic method for cell-specific metabolic labeling of RNA.
Sarah Nainar, Bonnie J Cuthbert, Nathan M Lim, Whitney E England, Ke Ke

Nat Methods· March 2020

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Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo.
Jonathan Hasselmann, Morgan A Coburn, Whitney England, Dario X Figueroa Velez, Sepideh Kiani Shabestari

Neuron· September 2019

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Expanding the Scope of RNA Metabolic Labeling with Vinyl Nucleosides and Inverse Electron-Demand Diels-Alder Chemistry.
Miles Kubota, Sarah Nainar, Shane M Parker, Whitney England, Filipp Furche

ACS Chem Biol· August 2019

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Cystic Fibrosis-Associated Stenotrophomonas maltophilia Strain-Specific Adaptations and Responses to pH.
Tara Gallagher, Joann Phan, Andrew Oliver, Alexander B Chase, Whitney E England

J Bacteriol· April 2019

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Assaying RNA structure with LASER-Seq.
Boris Zinshteyn, Dalen Chan, Whitney England, Chao Feng, Rachel Green

Nucleic Acids Res· January 2019

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Predictable Molecular Adaptation of Coevolving and Lytic Phage EfV12-phi1.
Stephen Wandro, Andrew Oliver, Tara Gallagher, Claudia Weihe, Whitney England

Front Microbiol· January 2019

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Metapopulation Structure of CRISPR-Cas Immunity in and Its Viruses.
Whitney E England, Ted Kim, Rachel J Whitaker

mSystems· October 2018

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