Publications by authors named "William Gaarde"

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Receptor interacting protein kinase 1 mediates murine acetaminophen toxicity independent of the necrosome and not through necroptosis.
Lily Dara, Heather Johnson, Jo Suda, Sanda Win, William Gaarde

Hepatology· December 2015

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Protein kinase C (PKC) participates in acetaminophen hepatotoxicity through c-jun-N-terminal kinase (JNK)-dependent and -independent signaling pathways.
Behnam Saberi, Maria D Ybanez, Heather S Johnson, William A Gaarde, Derick Han

Hepatology· April 2014

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Hepatic vascular endothelial growth factor regulates recruitment of rat liver sinusoidal endothelial cell progenitor cells.
Lin Wang, Xiangdong Wang, Lei Wang, Jenny D Chiu, Gijs van de Ven, William A Gaarde

Gastroenterology· December 2012

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Unique O-methoxyethyl ribose-DNA chimeric oligonucleotide induces an atypical melanoma differentiation-associated gene 5-dependent induction of type I interferon response.
Sebastien A Burel, Todd Machemer, Frank L Ragone, Hiroki Kato, Patrick Cauntay, William A Gaarde

J Pharmacol Exp Ther· July 2012

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Role of differentiation of liver sinusoidal endothelial cells in progression and regression of hepatic fibrosis in rats.
Guanhua Xie, Xiangdong Wang, Lei Wang, Lin Wang, Roscoe D Atkinson, William A Gaarde

Gastroenterology· April 2012

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Silencing glycogen synthase kinase-3beta inhibits acetaminophen hepatotoxicity and attenuates JNK activation and loss of glutamate cysteine ligase and myeloid cell leukemia sequence 1.
Mie Shinohara, Maria D Ybanez, Sanda Win, Tin Aung Than, Shilpa Jain, William A Gaarde

J Biol Chem· March 2010

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Differential effects of JNK1 and JNK2 inhibition on murine steatohepatitis and insulin resistance.
Rajat Singh, Yongjun Wang, Youqing Xiang, Kathryn E Tanaka, William A Gaarde

Hepatology· January 2009

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Regulation of H(2)O(2)-induced necrosis by PKC and AMP-activated kinase signaling in primary cultured hepatocytes.
Behnam Saberi, Mie Shinohara, Maria D Ybanez, Naoko Hanawa, William A Gaarde

Am J Physiol Cell Physiol· July 2008

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Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury.
Naoko Hanawa, Mie Shinohara, Behnam Saberi, William A Gaarde, Derick Han

J Biol Chem· May 2008

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Anti-inflammatory activity of inhaled IL-4 receptor-alpha antisense oligonucleotide in mice.
James G Karras, Jeffrey R Crosby, Mausumee Guha, David Tung, Doreen A Miller, William A Gaarde

Am J Respir Cell Mol Biol· March 2007

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c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity.
Basuki K Gunawan, Zhang-Xu Liu, Derick Han, Naoko Hanawa, William A Gaarde

Gastroenterology· July 2006

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Ezrin/radixin/moesin proteins are phosphorylated by TNF-alpha and modulate permeability increases in human pulmonary microvascular endothelial cells.
McKenzie Koss, Gordon R Pfeiffer, Ying Wang, Sharon T Thomas, Michael Yerukhimovich, William A Gaarde

J Immunol· January 2006

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MKK3 and -6-dependent activation of p38alpha MAP kinase is required for cytoskeletal changes in pulmonary microvascular endothelial cells induced by ICAM-1 ligation.
Qin Wang, Michael Yerukhimovich, William A Gaarde, Ian J Popoff, Claire M Doerschuk

Am J Physiol Lung Cell Mol Physiol· February 2005

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Inhibition of cell proliferation and cell cycle progression by specific inhibition of basal JNK activity: evidence that mitotic Bcl-2 phosphorylation is JNK-independent.
Lihua Du, Christopher S Lyle, Toria B Obey, William A Gaarde, Jeffrey A Muir

J Biol Chem· March 2004

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Reduction in glucagon receptor expression by an antisense oligonucleotide ameliorates diabetic syndrome in db/db mice.
Yin Liang, Melville C Osborne, Brett P Monia, Sanjay Bhanot, William A Gaarde

Diabetes· February 2004

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Activation of SRC tyrosine kinases in response to ICAM-1 ligation in pulmonary microvascular endothelial cells.
Qin Wang, Gordon R Pfeiffer, William A Gaarde

J Biol Chem· November 2003

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Shear-induced cyclooxygenase-2 via a JNK2/c-Jun-dependent pathway regulates prostaglandin receptor expression in chondrocytic cells.
James P Abulencia, Renee Gaspard, Zachary R Healy, William A Gaarde, John Quackenbush

J Biol Chem· August 2003

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Targets of c-Jun NH(2)-terminal kinase 2-mediated tumor growth regulation revealed by serial analysis of gene expression.
Olga Potapova, Sergey V Anisimov, Myriam Gorospe, Ryan H Dougherty, William A Gaarde

Cancer Res· June 2002

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Specific inhibition of PTEN expression reverses hyperglycemia in diabetic mice.
Madeline Butler, Robert A McKay, Ian J Popoff, William A Gaarde, Donna Witchell

Diabetes· April 2002

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