Publications by authors named "William Keyes"

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Enhanced branched-chain amino acid metabolism improves age-related reproduction in C. elegans.
Chen Lesnik, Rachel Kaletsky, Jasmine M Ashraf, Salman Sohrabi, Vanessa Cota, William Keyes

Nat Metab· April 2024

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Enhanced Branched-Chain Amino Acid Metabolism Improves Age-Related Reproduction in .
Chen Lesnik, Rachel Kaletsky, Jasmine M Ashraf, Salman Sohrabi, Vanessa Cota, William Keyes

bioRxiv· February 2024

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Cellular senescence and developmental defects.
Annabelle Klein, Muriel Rhinn, William M Keyes

FEBS J· March 2023

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Senescence diversity in muscle aging.
Matej Durik, William M Keyes

Nat Aging· July 2022

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Aberrant induction of p19Arf-mediated cellular senescence contributes to neurodevelopmental defects.
Muriel Rhinn, Irene Zapata-Bodalo, Annabelle Klein, Jean-Luc Plassat, Tania Knauer-Meyer, William M Keyes

PLoS Biol· June 2022

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Cell cycle gene regulation dynamics revealed by RNA velocity and deep-learning.
Andrea Riba, Attila Oravecz, Matej Durik, Sara Jiménez, Violaine Alunni, William M Keyes

Nat Commun· May 2022

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Endothelial cells give a boost to senescence surveillance.
Daniel Sampaio Gonçalves, William M Keyes

Genes Dev· May 2022

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High-throughput behavioral screen in C. elegans reveals Parkinson's disease drug candidates.
Salman Sohrabi, Danielle E Mor, Rachel Kaletsky, William Keyes, Coleen T Murphy

Commun Biol· February 2021

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Metformin rescues Parkinson's disease phenotypes caused by hyperactive mitochondria.
Danielle E Mor, Salman Sohrabi, Rachel Kaletsky, William Keyes, Alp Tartici

Proc Natl Acad Sci U S A· October 2020

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CREB Non-autonomously Controls Reproductive Aging through Hedgehog/Patched Signaling.
Nicole M Templeman, Vanessa Cota, William Keyes, Rachel Kaletsky, Coleen T Murphy

Dev Cell· July 2020

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The senotherapeutic drug ABT-737 disrupts aberrant p21 expression to restore liver regeneration in adult mice.
Birgit Ritschka, Tania Knauer-Meyer, Daniel Sampaio Gonçalves, Alba Mas, Jean-Luc Plassat, William M Keyes

Genes Dev· April 2020

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Cellular senescence in development, regeneration and disease.
Muriel Rhinn, Birgit Ritschka, William M Keyes

Development· October 2019

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An integrative tissue-network approach to identify and test human disease genes.
Victoria Yao, Rachel Kaletsky, William Keyes, Danielle E Mor, Aaron K Wong

Nat Biotechnol· October 2018

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Aberrant fatty acid metabolism in skeletal muscle contributes to insulin resistance in zinc transporter 7 ()-knockout mice.
Liping Huang, Surapun Tepaamorndech, Catherine P Kirschke, John W Newman, William R Keyes

J Biol Chem· May 2018

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Insulin Signaling Regulates Oocyte Quality Maintenance with Age via Cathepsin B Activity.
Nicole M Templeman, Shijing Luo, Rachel Kaletsky, Cheng Shi, Jasmine Ashraf, William Keyes

Curr Biol· March 2018

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Detection of Senescence Markers During Mammalian Embryonic Development.
Mekayla Storer, William M Keyes

Methods Mol Biol· January 2018

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The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration.
Birgit Ritschka, Mekayla Storer, Alba Mas, Florian Heinzmann, Mari Carmen Ortells, William M Keyes

Genes Dev· January 2017

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Zinc transporter 7 deficiency affects lipid synthesis in adipocytes by inhibiting insulin-dependent Akt activation and glucose uptake.
Surapun Tepaamorndech, Catherine P Kirschke, Theresa L Pedersen, William R Keyes, John W Newman

FEBS J· January 2016

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Genome-wide functional analysis of CREB/long-term memory-dependent transcription reveals distinct basal and memory gene expression programs.
Vanisha Lakhina, Rachel N Arey, Rachel Kaletsky, Amanda Kauffman, Geneva Stein, William Keyes

Neuron· January 2015

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Developing senescence to remodel the embryo.
Mekayla Storer, William M Keyes

Commun Integr Biol· October 2014

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New insights into skin stem cell aging and cancer.
M Carmen Ortells, William M Keyes

Biochem Soc Trans· June 2014

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An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology.
Diana Andrea Fernandes de Abreu, Antonio Caballero, Pascal Fardel, Nicholas Stroustrup, Zhunan Chen, William D Keyes

PLoS Genet· March 2014

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Rearranging senescence: transposable elements become active in aging cells (Comment on DOI 10.1002/bies.201300097).
William M Keyes

Bioessays· December 2013

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Senescence is a developmental mechanism that contributes to embryonic growth and patterning.
Mekayla Storer, Alba Mas, Alexandre Robert-Moreno, Matteo Pecoraro, M Carmen Ortells, William M Keyes

Cell· November 2013

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DPY30 regulates pathways in cellular senescence through ID protein expression.
Elisabeth Simboeck, Arantxa Gutierrez, Luca Cozzuto, Malte Beringer, Livia Caizzi, William M Keyes

EMBO J· August 2013

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