Publications by authors named "William Merrick"

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Inhibition of KDEL receptors remodels the tumor microenvironment for robust T cell independent tumor regression.
Shakti P Pattanayak, Hong Wang, Belinda Willard, Timothy A Chan, William C Merrick

bioRxiv· August 2025

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Plasticity of the mammalian integrated stress response.
Chien-Wen Chen, David Papadopoli, Krzysztof J Szkop, Bo-Jhih Guan, Mohammed Alzahrani, William C Merrick

Nature· May 2025

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A little protein makes big news in translation initiation.
William C Merrick

Mol Cell· January 2025

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Human eukaryotic initiation factor 4E (eIF4E) and the nucleotide-bound state of eIF4A regulate eIF4F binding to RNA.
Mario Servulo Izidoro, Masaaki Sokabe, Nancy Villa, William C Merrick, Christopher S Fraser

J Biol Chem· October 2022

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Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR.
Dawid Krokowski, Raul Jobava, Krzysztof J Szkop, Chien-Wen Chen, Xu Fu, William C Merrick

Cell Rep· July 2022

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eIF2A-knockout mice reveal decreased life span and metabolic syndrome.
Richard Anderson, Anchal Agarwal, Arnab Ghosh, Bo-Jhih Guan, Jackson Casteel, William C Merrick

FASEB J· November 2021

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Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress.
Raul Jobava, Yuanhui Mao, Bo-Jhih Guan, Di Hu, Dawid Krokowski, William C Merrick

Mol Cell· October 2021

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eIF4G has intrinsic G-quadruplex binding activity that is required for tiRNA function.
Shawn M Lyons, Prakash Kharel, Yasutoshi Akiyama, Sandeep Ojha, Dhwani Dave, William Merrick

Nucleic Acids Res· June 2020

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A Retrospective on eIF2A-and Not the Alpha Subunit of eIF2.
Anton A Komar, William C Merrick

Int J Mol Sci· March 2020

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Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F.
Jennifer Chu, Wenhan Zhang, Regina Cencic, Patrick B F O'Connor, Francis Robert, William C Merrick

Cell Rep· February 2020

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Protein Synthesis Initiation in Eukaryotic Cells.
William C Merrick, Graham D Pavitt

Cold Spring Harb Perspect Biol· December 2018

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A Unique ISR Program Determines Cellular Responses to Chronic Stress.
Bo-Jhih Guan, Vincent van Hoef, Raul Jobava, Orna Elroy-Stein, Leos S Valasek, William C Merrick

Mol Cell· December 2017

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The Celebration of 40 years of structural biology at Aarhus University as seen through the eyes of a translationalist.
William C Merrick

N Biotechnol· September 2017

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Changes in DSM-5 Diagnostic Criteria for Paraphilic Disorders.
William A Merrick

Arch Sex Behav· November 2016

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The eIF2A knockout mouse.
Andrei Golovko, Artyom Kojukhov, Bo-Jhih Guan, Benjamin Morpurgo, William C Merrick

Cell Cycle· November 2016

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Influence of translation factor activities on start site selection in six different mRNAs.
Daine Barth-Baus, C Ramana Bhasker, Wendy Zoll, William C Merrick

Translation (Austin)· January 2016

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Ternatin and improved synthetic variants kill cancer cells by targeting the elongation factor-1A ternary complex.
Jordan D Carelli, Steven G Sethofer, Geoffrey A Smith, Howard R Miller, Jillian L Simard, William C Merrick

Elife· December 2015

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eIF4F: a retrospective.
William C Merrick

J Biol Chem· October 2015

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OLA1 regulates protein synthesis and integrated stress response by inhibiting eIF2 ternary complex formation.
Huarong Chen, Renduo Song, Guohui Wang, Zonghui Ding, Chunying Yang, William C Merrick

Sci Rep· August 2015

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Rapid kinetics of iron responsive element (IRE) RNA/iron regulatory protein 1 and IRE-RNA/eIF4F complexes respond differently to metal ions.
Mateen A Khan, Jia Ma, William E Walden, William C Merrick, Elizabeth C Theil

Nucleic Acids Res· June 2014

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Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α.
Bo-Jhih Guan, Dawid Krokowski, Mithu Majumder, Christine L Schmotzer, Scot R Kimball, William C Merrick

J Biol Chem· May 2014

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Control not at initiation? Bah, humbug!
William C Merrick, Michael E Harris

EMBO J· January 2014

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A new framework for understanding IRES-mediated translation.
Anton A Komar, Barsanjit Mazumder, William C Merrick

Gene· July 2012

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Chimeric glutathione S-transferases containing inserts of kininogen peptides: potential novel protein therapeutics.
Amber A Bentley, Sergei M Merkulov, Yi Peng, Rita Rozmarynowycz, Xiaoping Qi, William C Merrick

J Biol Chem· June 2012

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Fe2+ binds iron responsive element-RNA, selectively changing protein-binding affinities and regulating mRNA repression and activation.
Jia Ma, Suranjana Haldar, Mateen A Khan, Sohani Das Sharma, William C Merrick

Proc Natl Acad Sci U S A· May 2012

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