Publications by authors named "William R Wikoff"

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Randomised, double-blind, placebo-controlled trial with azithromycin selects for anti-inflammatory microbial metabolites in the emphysematous lung.
Leopoldo N Segal, Jose C Clemente, Benjamin G Wu, William R Wikoff, Zhan Gao

Thorax· January 2017

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Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype.
Leopoldo N Segal, Jose C Clemente, Jun-Chieh J Tsay, Sergei B Koralov, Brian C Keller, William R Wikoff

Nat Microbiol· April 2016

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Serum phosphatidylethanolamine levels distinguish benign from malignant solitary pulmonary nodules and represent a potential diagnostic biomarker for lung cancer.
Johannes F Fahrmann, Dmitry Grapov, Brian C DeFelice, Sandra Taylor, Kyoungmi Kim, William R Wikoff

Cancer Biomark· March 2016

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Diacetylspermine Is a Novel Prediagnostic Serum Biomarker for Non-Small-Cell Lung Cancer and Has Additive Performance With Pro-Surfactant Protein B.
William R Wikoff, Samir Hanash, Brian DeFelice, Suzanne Miyamoto, Matt Barnett

J Clin Oncol· November 2015

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Metabolomic markers of altered nucleotide metabolism in early stage adenocarcinoma.
William R Wikoff, Dmitry Grapov, Johannes F Fahrmann, Brian DeFelice, William N Rom

Cancer Prev Res (Phila)· May 2015

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Systemic Metabolomic Changes in Blood Samples of Lung Cancer Patients Identified by Gas Chromatography Time-of-Flight Mass Spectrometry.
Suzanne Miyamoto, Sandra L Taylor, Dinesh K Barupal, Ayumu Taguchi, Gert Wohlgemuth, William R Wikoff

Metabolites· April 2015

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Pharmacometabolomic signature of ataxia SCA1 mouse model and lithium effects.
Bertrand Perroud, Paymaan Jafar-Nejad, William R Wikoff, Jennifer R Gatchel, Lu Wang

PLoS One· April 2014

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Is diabetes mellitus-linked amino acid signature associated with β-blocker-induced impaired fasting glucose?
Rhonda M Cooper-Dehoff, Wei Hou, Liming Weng, Rebecca A Baillie, Amber L Beitelshees, William R Wikoff

Circ Cardiovasc Genet· April 2014

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Pharmacometabolomics reveals racial differences in response to atenolol treatment.
William R Wikoff, Reginald F Frye, Hongjie Zhu, Yan Gong, Stephen Boyle

PLoS One· December 2013

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Metabolomics reveals amino acids contribute to variation in response to simvastatin treatment.
Miles Trupp, Hongjie Zhu, William R Wikoff, Rebecca A Baillie, Zhao-Bang Zeng

PLoS One· March 2013

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Identification of naturally occurring fatty acids of the myelin sheath that resolve neuroinflammation.
Peggy P Ho, Jennifer L Kanter, Amanda M Johnson, Hrishikesh K Srinagesh, Eun-Ju Chang, William R Wikoff

Sci Transl Med· June 2012

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Untargeted metabolomics identifies enterobiome metabolites and putative uremic toxins as substrates of organic anion transporter 1 (Oat1).
William R Wikoff, Megha A Nagle, Valentina L Kouznetsova, Igor F Tsigelny, Sanjay K Nigam

J Proteome Res· June 2011

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Variability analysis of human plasma and cerebral spinal fluid reveals statistical significance of changes in mass spectrometry-based metabolomics data.
Bridgit Crews, William R Wikoff, Gary J Patti, Hin-Koon Woo, Ewa Kalisiak

Anal Chem· October 2009

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Response and recovery in the plasma metabolome tracks the acute LCMV-induced immune response.
William R Wikoff, Ewa Kalisak, Sunia Trauger, Marianne Manchester, Gary Siuzdak

J Proteome Res· July 2009

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Novel multiprotein complexes identified in the hyperthermophilic archaeon Pyrococcus furiosus by non-denaturing fractionation of the native proteome.
Angeli Lal Menon, Farris L Poole, Aleksandar Cvetkovic, Sunia A Trauger, Ewa Kalisiak, William R Wikoff

Mol Cell Proteomics· April 2009

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Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites.
William R Wikoff, Andrew T Anfora, Jun Liu, Peter G Schultz, Scott A Lesley

Proc Natl Acad Sci U S A· March 2009

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Organic anion transporter 3 contributes to the regulation of blood pressure.
Volker Vallon, Satish A Eraly, William R Wikoff, Timo Rieg, Gregory Kaler

J Am Soc Nephrol· September 2008

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Metabolomic analysis of the cerebrospinal fluid reveals changes in phospholipase expression in the CNS of SIV-infected macaques.
William R Wikoff, Gurudutt Pendyala, Gary Siuzdak, Howard S Fox

J Clin Invest· July 2008

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Multiple organic anion transporters contribute to net renal excretion of uric acid.
Satish A Eraly, Volker Vallon, Timo Rieg, Jon A Gangoiti, William R Wikoff

Physiol Genomics· April 2008

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Metabolomics identifies perturbations in human disorders of propionate metabolism.
William R Wikoff, Jon A Gangoiti, Bruce A Barshop, Gary Siuzdak

Clin Chem· December 2007

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Mobilization of pro-inflammatory lipids in obese Plscr3-deficient mice.
David M Mutch, Grace O'Maille, William R Wikoff, Therese Wiedmer, Peter J Sims

Genome Biol· June 2007

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Mass spectrometry reveals specific and global molecular transformations during viral infection.
Eden P Go, William R Wikoff, Zhouxin Shen, Grace O'Maille, Hirotoshi Morita

J Proteome Res· September 2006

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Time-resolved molecular dynamics of bacteriophage HK97 capsid maturation interpreted by electron cryo-microscopy and X-ray crystallography.
William R Wikoff, James F Conway, Jinghua Tang, Kelly K Lee, Lu Gan

J Struct Biol· March 2006

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The refined structure of a protein catenane: the HK97 bacteriophage capsid at 3.44 A resolution.
Charlotte Helgstrand, William R Wikoff, Robert L Duda, Roger W Hendrix, John E Johnson

J Mol Biol· December 2003

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Crystallization and preliminary analysis of a dsDNA bacteriophage capsid intermediate: Prohead II of HK97.
William R Wikoff, Zhiwei Che, Robert L Duda, Roger W Hendrix, John E Johnson

Acta Crystallogr D Biol Crystallogr· December 2003

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