Publications by authors named "Wing C Lee"

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Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS.
Mercedes Prudencio, Veronique V Belzil, Ranjan Batra, Christian A Ross, Tania F Gendron, Wing C Lee

Nat Neurosci· August 2015

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Prevalence and Characteristics of Chinese Patients With Duchenne and Becker Muscular Dystrophy: A Territory Wide Collaborative Study in Hong Kong.
Sophelia H S Chan, Ivan F M Lo, Sharon W W Cherk, Wai Wai Cheng, Eva L W Fung, Wing Cheong Lee

Child Neurol Open· May 2015

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Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency.
Wing C Lee, Sandra Almeida, Mercedes Prudencio, Thomas R Caulfield, Yong-Jie Zhang

Hum Mol Genet· March 2014

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Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS.
Tania F Gendron, Kevin F Bieniek, Yong-Jie Zhang, Karen Jansen-West, Peter E A Ash, Wing C Lee

Acta Neuropathol· December 2013

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The dual functions of the extreme N-terminus of TDP-43 in regulating its biological activity and inclusion formation.
Yong-Jie Zhang, Thomas Caulfield, Ya-Fei Xu, Tania F Gendron, Jaime Hubbard, Wing Cheung Lee

Hum Mol Genet· August 2013

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Misregulation of human sortilin splicing leads to the generation of a nonfunctional progranulin receptor.
Mercedes Prudencio, Karen R Jansen-West, Wing C Lee, Tania F Gendron, Yong-Jie Zhang

Proc Natl Acad Sci U S A· December 2012

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Progranulin regulates neuronal outgrowth independent of sortilin.
Jennifer Gass, Wing C Lee, Casey Cook, Nicole Finch, Caroline Stetler

Mol Neurodegener· July 2012

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Molecular characterization of mutations that cause globoid cell leukodystrophy and pharmacological rescue using small molecule chemical chaperones.
Wing C Lee, Dongcheul Kang, Ena Causevic, Aimee R Herdt, Elizabeth A Eckman

J Neurosci· April 2010

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Single-dose intracerebroventricular administration of galactocerebrosidase improves survival in a mouse model of globoid cell leukodystrophy.
Wing C Lee, Yuen K Tsoi, Frederick J Troendle, Michael W DeLucia, Zeshan Ahmed

FASEB J· August 2007

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Suppression of galactosylceramidase (GALC) expression in the twitcher mouse model of globoid cell leukodystrophy (GLD) is caused by nonsense-mediated mRNA decay (NMD).
Wing C Lee, Yuen K Tsoi, Chad A Dickey, Michael W Delucia, Dennis W Dickson

Neurobiol Dis· August 2006

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Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression.
Chad A Dickey, Peter Ash, Natalia Klosak, Wing C Lee, Leonard Petrucelli

Mol Neurodegener· July 2006

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Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho- and caspase-3-cleaved tau species.
Chad A Dickey, Mei Yue, Wen-Lang Lin, Dennis W Dickson, Judith H Dunmore, Wing C Lee

J Neurosci· June 2006

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HSP induction mediates selective clearance of tau phosphorylated at proline-directed Ser/Thr sites but not KXGS (MARK) sites.
Chad A Dickey, Judith Dunmore, Bingwei Lu, Ji-Wu Wang, Wing C Lee

FASEB J· April 2006

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Enzyme replacement therapy results in substantial improvements in early clinical phenotype in a mouse model of globoid cell leukodystrophy.
Wing C Lee, Andrew Courtenay, Frederick J Troendle, Melody L Stallings-Mann, Chad A Dickey

FASEB J· September 2005

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