Publications by authors named "Wing-Yan So"

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Gene therapy targeting key beta cell regulators as a potential intervention for diabetes.
Wing Yan So, Weiping Han

EMBO Mol Med· July 2024

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Paired box 6 gene delivery preserves beta cells and improves islet transplantation efficacy.
Wing Yan So, Yilie Liao, Wai Nam Liu, Guy A Rutter, Weiping Han

EMBO Mol Med· December 2023

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Successful targeting of PD-1/PD-L1 with chimeric antigen receptor-natural killer cells and nivolumab in a humanized mouse cancer model.
Wai Nam Liu, Wing Yan So, Sarah L Harden, Shin Yie Fong, Melissa Xin Yu Wong, Wilson Wei Sheng Tan

Sci Adv· November 2022

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Paired box 6 programs essential exocytotic genes in the regulation of glucose-stimulated insulin secretion and glucose homeostasis.
Wing Yan So, Wai Nam Liu, Adrian Kee Keong Teo, Guy A Rutter, Weiping Han

Sci Transl Med· June 2021

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IP-assisted CSN-COP1 competition regulates a CRL4-ETV5 proteolytic checkpoint to safeguard glucose-induced insulin secretion.
Hong Lin, Yuan Yan, Yifan Luo, Wing Yan So, Xiayun Wei

Nat Commun· April 2021

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Fibroblast growth factor 21 protects against lipotoxicity-induced pancreatic β-cell dysfunction via regulation of AMPK signaling and lipid metabolism.
Ting Xie, Wing Yan So, Xing Yu Li, Po Sing Leung

Clin Sci (Lond)· October 2019

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Insulinotropic effects of GPR120 agonists are altered in obese diabetic and obese non-diabetic states.
Dan Zhang, Wing Yan So, Yi Wang, Shang Ying Wu, Qianni Cheng

Clin Sci (Lond)· February 2017

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Irisin ameliorates hepatic glucose/lipid metabolism and enhances cell survival in insulin-resistant human HepG2 cells through adenosine monophosphate-activated protein kinase signaling.
Wing Yan So, Po Sing Leung

Int J Biochem Cell Biol· September 2016

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Fibroblast Growth Factor 21 As an Emerging Therapeutic Target for Type 2 Diabetes Mellitus.
Wing Yan So, Po Sing Leung

Med Res Rev· July 2016

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Niacin-induced hyperglycemia is partially mediated via niacin receptor GPR109a in pancreatic islets.
Lihua Chen, Wing Yan So, Stephen Y T Li, Qianni Cheng, Barbara J Boucher

Mol Cell Endocrinol· March 2015

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High glucose represses β-klotho expression and impairs fibroblast growth factor 21 action in mouse pancreatic islets: involvement of peroxisome proliferator-activated receptor γ signaling.
Wing Yan So, Qianni Cheng, Lihua Chen, Carmella Evans-Molina, Aimin Xu

Diabetes· November 2013

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Estrogen controls embryonic stem cell proliferation via store-operated calcium entry and the nuclear factor of activated T-cells (NFAT).
Chun-Kit Wong, Wing-Yan So, Sau-Kwan Law, Fung-Ping Leung, Ka-Long Yau

J Cell Physiol· June 2012

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Spatialization design: comparing points and landscapes.
Melanie Tory, David Sprague, Fuqu Wu, Wing Yan So, Tamara Munzner

IEEE Trans Vis Comput Graph· December 2007

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